--- title: "VIP: Dosing & Vendor Prices — BodyHackGuide" description: "VIP: dosing protocols, mechanism & side effects. Compare 1 verified vendor prices." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compounds", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "VIP" } ] }, { "@context": "https://schema.org", "@type": "Product", "name": "VIP", "description": "VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. It is a member of the glucagon superfamily. 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It is a member of the glucagon superfamily. VIP functions as a potent vasodilator and bronchodilator, as a neuromodulator in the brain (circadian rhythm, neuroprotection), as an immunomodulator with predominantly anti-inflammatory actions, and as a GI motility regulator. VIP has attracted research interest for CIRS (Chronic Inflammatory Response Syndrome), mast cell activation, small fiber neuropathy, and autonomic nervous system regulation. 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It is a member of the glucagon superfamily. VIP functions as a potent vasodilator and bronchodilator, as a neuromodulator in the brain (circadian rhythm, neuroprotection), as an immunomodulator with predominantly anti-inflammatory actions, and as a GI motility regulator. VIP has attracted research interest for CIRS (Chronic Inflammatory Response Syndrome), mast cell activation, small fiber neuropathy, and autonomic nervous system regulation. It is one of the few neuropeptides with simultaneous central, peripheral, and immune functions.", "activeIngredient": "VIP", "administrationRoute": "Subcutaneous, Intranasal, Intravenous", "mechanismOfAction": "VIP acts on VPAC1 and VPAC2 receptors (G-protein coupled, Gs-linked), stimulating adenylyl cyclase and elevating cAMP in target cells. Central effects include modulation of the suprachiasmatic nucleus (SCN) — VIP is a key SCN neuropeptide regulating circadian rhythm synchronization. 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BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompound%2Fvip) 100K+ researchers trust BodyHackGuide — Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 2. [Compounds](/compare) 3. VIP ![Ion Peptide logo](https://ionpeptide.com/wp-content/uploads/2025/08/ion-peptide-logo-1-300x148.jpg) Best price right now $7.90/mg · $79.00 for 10mg at Ion Peptide [Buy at Ion Peptide](https://www.bodyhackguide.co/go/ion-peptide?utm_source=compound-sticky-bar&utm_campaign=f36b1e49-ab10-48f0-9eb6-b08d923f77c3&utm_medium=best-price-cta) [Where to buy VIP](/buy/vip) [VIP coupon codes](/coupons/vip) [VIP protocol](/protocol/vip) [Alternatives to VIP](/alternatives-to/vip) [VIP side effects](/side-effects/vip) 1. [Home](/) 3. [Compounds](/compare) 5. VIP # VIP Nootropic Clinical Download PDF Also known as: Vasoactive Intestinal Peptide, Vasoactive Intestinal Polypeptide, PHM-27 precursor neuropeptide VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. It is a member of the glucagon superfamily. Half-Life: ~1-2 minutes (plasma). VIP is very rapidly degraded by circulating peptidases, so systemic exposure is extremely short-lived regardless of administration route. Subcutaneous or intranasal absorption may modestly prolong the apparent duration of local/systemic effect, but this has not been well characterized in humans. Route: Subcutaneous, Intranasal, Intravenous MW: 3326.8 Last reviewed: Sep 3, 2026 [ Nootropic Category ](/wiki#cat-nootropic) Clinical Research Stage OverviewChemical InfoDosing & ProtocolsInteractionsResearchCompare Prices1 Related ## Overview ### Best Price Available ![Ion Peptide logo](https://ionpeptide.com/wp-content/uploads/2025/08/ion-peptide-logo-1-300x148.jpg) Ion Peptide $79.00 1 vial · vial [Buy Now](https://ionpeptide.com/product/vip/?ref=reddit15) Compare 1 vendor ### At A Glance Mechanism VIP acts on VPAC1 and VPAC2 receptors (G-protein coupled, Gs-linked), stimulating adenylyl cyclase and elevating cAMP in target cells. Central effects include modulation of the suprachiasmatic nucleus (SCN) — VIP is a key SCN neuropeptide regulating circadian rhythm synchronizati… Half-Life ~1-2 minutes (plasma). VIP is very rapidly degraded by circulating peptidases, so systemic exposure is extremely short-lived regardless of administration route. Subcutaneous or intranasal absorption may modestly prolong the apparent duration of local/systemic effect, but this has not been well characterized in humans. Dosing once or twice daily Dose Range 50mcg Routes Subcutaneous Intranasal Intravenous Common Vials 10mg Potential Benefits Potent anti-inflammatory signaling — inhibits TNF-α, IL-6, IL-12 via cAMP pathway Circadian rhythm regulation through suprachiasmatic nucleus (SCN) VPAC receptor activation Bronchodilation — potential research application in airway inflammation models Vasodilation and blood flow regulation in peripheral vascular research Neuroprotection — VPAC2 agonism supports neuronal survival in excitotoxicity models CIRS/mast cell activation research — increasingly studied in chronic inflammatory syndromes Gut motility modulation and GI mucosal protection Safety Notes Common Facial flushing Hypotension (vasodilatory effect) Nausea Tachycardia at higher doses Serious Significant hypotension risk at IV doses — not for unsupervised IV use Bronchospasm paradox (rare) No long-term human safety data for subcutaneous research use ### Overview VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. It is a member of the glucagon superfamily. VIP functions as a potent vasodilator and bronchodilator, as a neuromodulator in the brain (circadian rhythm, neuroprotection), as an immunomodulator with predominantly anti-inflammatory actions, and as a GI motility regulator. VIP has attracted research interest for CIRS (Chronic Inflammatory Response Syndrome), mast cell activation, small fiber neuropathy, and autonomic nervous system regulation. It is one of the few neuropeptides with simultaneous central, peripheral, and immune functions. ## Chemical Information IUPAC Name Not yet available CAS Number Not yet available Molecular Formula Not yet available Molecular Mass 3326.8 Amino Acid Sequence HSDAVFTDNYTRLRKQMAVKKYLNSILN (28 residues; native C-terminal amide, His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2) ## Dosing & Protocols ### Unlock Dosing Protocols Free account gets you: - View beginner, intermediate & advanced protocols - See weight-based dosing calculations - Access cycle length & frequency data [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Research ### Unlock Research Data Free account gets you: - Browse PubMed study summaries - See clinical trial phases & results - Access mechanism of action details [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Interactions Interaction and contraindication data is being compiled for VIP. Check back soon. General Safety Note Always consult a qualified healthcare professional before combining research compounds. Interactions may exist that are not yet documented. Best Price $79.00 Best $/mg $7.9000 Vendors 1 Listings 1 vial [Sign in for alerts ](/auth) Form Allvial Sort Price $/mg Vendor Vendor Product Form Qty Price $/mg Coupon ![Ion Peptide logo](https://ionpeptide.com/wp-content/uploads/2025/08/ion-peptide-logo-1-300x148.jpg) [Ion Peptide](/vendor/ion-peptide) [70 ](/vendor-trust-scorecard) 🇺🇸 US 🌍 International VIP 10mg vial 1 vial ● In Stock $79.00 BEST $7.900 — [Buy](https://ionpeptide.com/product/vip/?ref=reddit15) Get VIP Price Drop Alerts Set a target price and we'll notify you when any vendor drops below it. Current lowest: $79.00 [Sign in to set alerts](/auth) ### Sign in to leave a review Reviews on BodyHackGuide are tied to verified user accounts and moderated before publishing. Sign in (free, no spam) to share your experience with VIP. [Sign in](/auth) Current low $79.00 as of Apr 22, 2026 7-day low — no 7d data yet 30-day low — no 30d data yet 30-day change — baseline building Tracking since Apr 22, 2026 · 1 data point ### Vendors Selling VIP [ ![Ion Peptide logo](https://ionpeptide.com/wp-content/uploads/2025/08/ion-peptide-logo-1-300x148.jpg) #### Ion Peptide 4.5 1 listing · from $79.00 ](/vendor/ion-peptide) How we score these vendors Every supplier above is graded 0–100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank. [View Scorecard](/vendors/scorecard) ### Related Compounds [View All](/wiki) [ ### Alpha-GPC Nootropic Phase 4 Alpha-GPC (chemical name L-alpha-glycerylphosphorylcholine; pharmaceutical name choline alfoscerate) is a naturally occurring cholinergic compound that serves as a highly bioavailable precursor to both acetylcholine (the primary neurotransmitter of the cholinergic system, central to learning, memory, attention, and neuromuscular function) and phosphatidylcholine (the principal phospholipid building block of neuronal cell membranes). 9 studies View Profile ](/compound/alpha-gpc)[ ### Caffeine Nootropic Preclinical Caffeine (1,3,7-trimethylxanthine) is a natural methylxanthine alkaloid found in the seeds, fruits, leaves, and bark of over 60 plant species — most notably Coffea (coffee), Camellia sinensis (tea), Theobroma cacao (cacao), Paullinia cupana (guaraná), Ilex paraguariensis (yerba mate), and Cola acuminata (kola nut). 47499 studies View Profile ](/compound/caffeine)[ ### CDP-Choline Nootropic Phase 4 CDP-choline (cytidine 5'-diphosphocholine, pharmaceutical name citicoline) is a naturally occurring intracellular intermediate in the Kennedy pathway for phosphatidylcholine synthesis — the primary biochemical route by which all nucleated cells produce the dominant membrane phospholipid. 56 studies View Profile ](/compound/cdp-choline)[ ### Inositol Nootropic Preclinical Inositol is a naturally-occurring cyclic sugar alcohol (cyclohexanehexol) that functions as a critical structural component of cell membranes and a second-messenger precursor in intracellular signaling. 53071 studies View Profile ](/compound/inositol)[ ### L-Tryptophan Nootropic Preclinical L-Tryptophan is one of the nine essential amino acids — meaning the human body cannot synthesize it and must obtain it from dietary protein — and is the direct metabolic precursor to serotonin, melatonin, and (via a separate route) the vitamin niacin (nicotinamide / NAD+). 80432 studies View Profile ](/compound/l-tryptophan)[ ### Magnesium L-Threonate Nootropic Preclinical Magnesium L-Threonate is a proprietary chelated form of magnesium in which the magnesium cation is bound to L-threonic acid — a metabolite of ascorbic acid (vitamin C) — forming the salt commonly marketed under the brand name Magtein. 207 studies View Profile ](/compound/magnesium-l-threonate) [ View Full Dosage Guide → Protocols, calculator & safety for VIP ](/guides/dosage/vip) ### Best Price ![Ion Peptide logo](https://ionpeptide.com/wp-content/uploads/2025/08/ion-peptide-logo-1-300x148.jpg) Ion Peptide $79.00 [Buy Now](https://ionpeptide.com/product/vip/?ref=reddit15) 1 vendors · 1 listings ### Research Score 45 0 PubMed studies ### Quality Indicators Data Completeness 63% Description Mechanism of Action Chemical Data Dosing Protocols Safety Profile PubMed Studies Interactions Vendor Listings ### Quick Facts Half-Life ~1-2 minutes (plasma). VIP is very rapidly degraded by circulating peptidases, so systemic exposure is extremely short-lived regardless of administration route. Subcutaneous or intranasal absorption may modestly prolong the apparent duration of local/systemic effect, but this has not been well characterized in humans. Molecular Weight 3326.8 Administration Subcutaneous, Intranasal, Intravenous Trial Phase Clinical ### Safety Profile Common Side Effects - • Facial flushing - • Hypotension (vasodilatory effect) - • Nausea - • Tachycardia at higher doses [Full Dosage Guide](/guides/dosage/vip)[Calculate Your Dose](/tools/reconstitution) Research Disclaimer This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use. ## Frequently Asked Questions What is VIP used for in research? VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. It is a member of the glucagon superfamily. VIP functions as a potent vasodilator and bronchodilator, as a neuromodulator in the brain (circadian rhythm, neuroprotection), as an immunomodulator with predominantly anti-inflammatory actions, and as a GI motility regulator. VIP has attracted research interest for CIRS (Chronic Inflammatory Response Syndrome), mast cell activation, small fiber neuropathy, and autonomic nervous system regulation. It is one of the few neuropeptides with simultaneous central, peripheral, and immune functions. What forms does VIP come in? VIP is available in vial form. How much does VIP cost? Prices start at $79.00 across 1 verified vendor. How do I compare VIP vendors? Compare prices, payment methods, shipping, and COA scores across 1 vendor. ## Research Tools [ ### Peptide Calculator Reconstitution & syringe units ](/tools/reconstitution)[ ### Reconstitution Guide How to mix, step by step ](/guides/how-to-reconstitute-peptides)[ ### Nasal Spray Calc mL per actuation ](/tools/intranasal)[ ### Half-Life Visualizer Decay curves ](/tools/halflife) ## Related Compounds [View All](/wiki) [ ### Alpha-GPC Nootropic Phase 4 Alpha-GPC (chemical name L-alpha-glycerylphosphorylcholine; pharmaceutical name choline alfoscerate) is a naturally occurring cholinergic compound that serves as a highly bioavailable precursor to both acetylcholine (the primary neurotransmitter of the cholinergic system, central to learning, memory, attention, and neuromuscular function) and phosphatidylcholine (the principal phospholipid building block of neuronal cell membranes). 9 studies View Profile ](/compound/alpha-gpc)[ ### Caffeine Nootropic Preclinical Caffeine (1,3,7-trimethylxanthine) is a natural methylxanthine alkaloid found in the seeds, fruits, leaves, and bark of over 60 plant species — most notably Coffea (coffee), Camellia sinensis (tea), Theobroma cacao (cacao), Paullinia cupana (guaraná), Ilex paraguariensis (yerba mate), and Cola acuminata (kola nut). 47499 studies View Profile ](/compound/caffeine)[ ### CDP-Choline Nootropic Phase 4 CDP-choline (cytidine 5'-diphosphocholine, pharmaceutical name citicoline) is a naturally occurring intracellular intermediate in the Kennedy pathway for phosphatidylcholine synthesis — the primary biochemical route by which all nucleated cells produce the dominant membrane phospholipid. 56 studies View Profile ](/compound/cdp-choline)[ ### Inositol Nootropic Preclinical Inositol is a naturally-occurring cyclic sugar alcohol (cyclohexanehexol) that functions as a critical structural component of cell membranes and a second-messenger precursor in intracellular signaling. 53071 studies View Profile ](/compound/inositol)[ ### L-Tryptophan Nootropic Preclinical L-Tryptophan is one of the nine essential amino acids — meaning the human body cannot synthesize it and must obtain it from dietary protein — and is the direct metabolic precursor to serotonin, melatonin, and (via a separate route) the vitamin niacin (nicotinamide / NAD+). 80432 studies View Profile ](/compound/l-tryptophan)[ ### Magnesium L-Threonate Nootropic Preclinical Magnesium L-Threonate is a proprietary chelated form of magnesium in which the magnesium cation is bound to L-threonic acid — a metabolite of ascorbic acid (vitamin C) — forming the salt commonly marketed under the brand name Magtein. 207 studies View Profile ](/compound/magnesium-l-threonate) Free 2026 Peptide Cheat Sheet — 50 pages, PDF Reconstitution math, concentration charts, half-lives, and vendor trust tiers. The reference we wish we had on day one. [Download Free](/guides/peptide-cheat-sheet-download?utm_source=compound-vip) ### Need bloodwork before starting? Full hormone + metabolic panels from Anabolic Insights. Code CHONCH for first-order discount. [Order Bloodwork](https://anabolicinsights.ai/?ref=nwm2zjb) ![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub — compound pricing, brain health protocols, dosing tools, and vendor reviews. 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