--- title: "Semax P-21: Dosing & Vendor Prices | BodyHackGuide" description: "Semax P-21: dosing protocols, mechanism & side effects, 1 PubMed results. Compare current vendor prices." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compounds", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "Semax P-21" } ] }, { "@context": "https://schema.org", "@type": "MedicalWebPage", "name": "Semax P-21", "description": "Semax P-21 is a hybrid synthetic peptide combining structural motifs from Semax and P-21 into a single molecule. Marketed as a one-shot drop-in for users running both compounds, the rationale is convenience (one peptide instead of two) and additive cognitive + anxiolytic effects. The peer-reviewed literature on this specific hybrid is essentially absent — most pharmacological characterization is by analogy to the constituent peptides. Treat it as Semax-equivalent on cognition and P-21-equivalent on anxiolysis until stronger primary data emerges.", "lastReviewed": "2026-09-14T19:42:00.834Z", "url": "https://www.bodyhackguide.co/compound/semax-p21", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "reviewedBy": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" }, "mainContentOfPage": { "@type": "WebPageElement", "cssSelector": "main" }, "about": { "@type": "Drug", "name": "Semax P-21", "alternateName": [ "Semax-P21", "SemaxP21", "Semax + P21 Hybrid" ], "description": "Semax P-21 is a hybrid synthetic peptide combining structural motifs from Semax and P-21 into a single molecule. Marketed as a one-shot drop-in for users running both compounds, the rationale is convenience (one peptide instead of two) and additive cognitive + anxiolytic effects. The peer-reviewed literature on this specific hybrid is essentially absent — most pharmacological characterization is by analogy to the constituent peptides. Treat it as Semax-equivalent on cognition and P-21-equivalent on anxiolysis until stronger primary data emerges.", "activeIngredient": "Semax P-21", "mechanismOfAction": "Important framing: \"Semax P-21\" is not a single characterized compound. It is a speculative user stack combining two separate, unrelated peptides - Semax and P-21 (P021). No pharmacological study of the combination exists, so the profile below is inferred from each constituent individually. Semax (primary effects): A synthetic ACTH(4-7) analog that increases BDNF and NGF expression, modulates dopaminergic and serotonergic signaling, and supports attention and neuroprotection. Semax has documented clinical use in Russia. P-21 / P021 (primary effects - animal data only): P021 is a ciliary neurotrophic factor (CNTF)-derived small-molecule peptide mimetic (Ac-DGGL(A)G-NH2). It enhances hippocampal (dentate gyrus) neurogenesis and increases BDNF expression by inhibiting the leukemia inhibitory factor (LIF) signaling pathway, and it reduces tau hyperphosphorylation through a BDNF-mediated decrease in GSK-3-beta (a major tau kinase) activity. These effects have been demonstrated only in cell and rodent models (PMID: 27400746). Correction: Earlier claims that P-21 acts via GABA-A modulation or NGF upregulation were inaccurate - that anxiolytic/GABAergic profile belongs to the Selank/Semax family, not to P021. BDNF upregulation and neurogenesis are the intended primary effects of these peptides, not \"side effects.\"", "legalStatus": "Not approved for human use (research chemical)", "warning": "For research purposes only. Not for human consumption." } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is Semax P-21 used for in research?", "acceptedAnswer": { "@type": "Answer", "text": "Semax P-21 is a hybrid synthetic peptide combining structural motifs from Semax and P-21 into a single molecule. Marketed as a one-shot drop-in for users running both compounds, the rationale is convenience (one peptide instead of two) and additive cognitive + anxiolytic effects. The peer-reviewed literature on this specific hybrid is essentially absent — most pharmacological characterization is by analogy to the constituent peptides. Treat it as Semax-equivalent on cognition and P-21-equivalent on anxiolysis until stronger primary data emerges." } }, { "@type": "Question", "name": "What forms does Semax P-21 come in?", "acceptedAnswer": { "@type": "Answer", "text": "Semax P-21 is available in vials, capsules, and sprays forms." } }, { "@type": "Question", "name": "How much does Semax P-21 cost?", "acceptedAnswer": { "@type": "Answer", "text": "Pricing varies by vendor and form." } }, { "@type": "Question", "name": "How do I compare Semax P-21 vendors?", "acceptedAnswer": { "@type": "Answer", "text": "Compare prices, payment methods, shipping, and COA scores across 0 vendors." } } ] }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, vendor price comparisons, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+, enter siteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompound%2Fsemax-p21) Compare notes with other researchers. Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 3. [Compounds](/compare) 5. Semax P-21 [🛒 Where to buy Semax P-21](/buy/semax-p21)[🏷️ Semax P-21 coupon codes](/coupons/semax-p21)[📋 Semax P-21 protocol](/protocol/semax-p21)[🔄 Alternatives to Semax P-21](/alternatives-to/semax-p21)[⚠️ Semax P-21 side effects](/side-effects/semax-p21) 1. [Home](/) 3. [Compounds](/compare) 5. Semax P-21 # Semax P-21 Nootropic Peptide Preclinical Download PDF Also known as: Semax-P21, SemaxP21, Semax + P21 Hybrid Semax P-21 is a hybrid synthetic peptide combining structural motifs from Semax and P-21 into a single molecule. Marketed as a one-shot drop-in for users running both compounds, the rationale is convenience (one peptide instead of two) and additive cognitive + anxiolytic effects. The peer-reviewed literature on this specific hybrid is essentially absent — most pharmacological characterization is by analogy to the constituent peptides. Half-Life: No combined-product pharmacokinetics exist. Semax (intranasal): the intact peptide is rapidly metabolized (on the order of minutes), though downstream BDNF/neurotrophic effects outlast the peptide itself. P-21 / P021: a small molecule with pharmacokinetics suitable for oral dosing in animal studies; no human PK data. MW: Not a single molecule - "Semax P-21" is two separate peptides, so no combined molecular weight applies. Per constituent: Semax (heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro) is approximately 813.9 g/mol; P-21 / P021 (Ac-DGGL(A)G-NH2, a CNTF-derived peptide mimetic) is a low-molecular-weight, blood-brain-barrier-permeable small molecule. [1 PubMed Results](https://pubmed.ncbi.nlm.nih.gov/?term=Semax%20P-21) Last reviewed: Sep 14, 2026 [ 1 PubMed Results ](https://pubmed.ncbi.nlm.nih.gov/?term=Semax%20P-21)[ Nootropic Peptide Category ](/wiki#cat-nootropic-peptide) Preclinical Research Stage OverviewChemical InfoDosing & ProtocolsInteractionsResearchCompare PricesRelated ## Overview ### At A Glance Mechanism Important framing: "Semax P-21" is not a single characterized compound. It is a speculative user stack combining two separate, unrelated peptides - Semax and P-21 (P021). No pharmacological study of the combination exists, so the profile below is inferred from each constituent … Half-Life No combined-product pharmacokinetics exist. Semax (intranasal): the intact peptide is rapidly metabolized (on the order of minutes), though downstream BDNF/neurotrophic effects outlast the peptide itself. P-21 / P021: a small molecule with pharmacokinetics suitable for oral dosing in animal studies; no human PK data. Safety Notes Common Mild nasal irritation Brief alertness spike ### Mechanism of Action **Important framing:** "Semax P-21" is not a single characterized compound. It is a speculative user stack combining two separate, unrelated peptides - Semax and P-21 (P021). No pharmacological study of the combination exists, so the profile below is inferred from each constituent individually. **Semax (primary effects):** A synthetic ACTH(4-7) analog that increases BDNF and NGF expression, modulates dopaminergic and serotonergic signaling, and supports attention and neuroprotection. Semax has documented clinical use in Russia. **P-21 / P021 (primary effects - animal data only):** P021 is a ciliary neurotrophic factor (CNTF)-derived small-molecule peptide mimetic (Ac-DGGL(A)G-NH2). It enhances hippocampal (dentate gyrus) neurogenesis and increases BDNF expression by inhibiting the leukemia inhibitory factor (LIF) signaling pathway, and it reduces tau hyperphosphorylation through a BDNF-mediated decrease in GSK-3-beta (a major tau kinase) activity. These effects have been demonstrated only in cell and rodent models (PMID: 27400746). **Correction:** Earlier claims that P-21 acts via GABA-A modulation or NGF upregulation were inaccurate - that anxiolytic/GABAergic profile belongs to the Selank/Semax family, not to P021. BDNF upregulation and neurogenesis are the intended primary effects of these peptides, not "side effects." ### Overview Semax P-21 is a **hybrid synthetic peptide** combining structural motifs from [Semax](/compound/semax) and [P-21](/compound/p21) into a single molecule. Marketed as a one-shot drop-in for users running both compounds, the rationale is convenience (one peptide instead of two) and additive cognitive + anxiolytic effects. The peer-reviewed literature on this specific hybrid is essentially absent — most pharmacological characterization is by analogy to the constituent peptides. Treat it as Semax-equivalent on cognition and P-21-equivalent on anxiolysis until stronger primary data emerges. ## Chemical Information IUPAC Name Not yet available CAS Number Not yet available Molecular Formula C40H58N14O11 Molecular Mass Not a single molecule - "Semax P-21" is two separate peptides, so no combined molecular weight applies. Per constituent: Semax (heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro) is approximately 813.9 g/mol; P-21 / P021 (Ac-DGGL(A)G-NH2, a CNTF-derived peptide mimetic) is a low-molecular-weight, blood-brain-barrier-permeable small molecule. Amino Acid Sequence Semax: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP) - ACTH(4-7) extended with a C-terminal Pro-Gly-Pro. P-21 / P021: Ac-DGGL(A)G-NH2, an N-acetylated, C-amidated peptide mimetic derived from the active region (Peptide-6) of ciliary neurotrophic factor (CNTF). These are two distinct peptides, not one sequence. ## Dosing & Protocols ### Dosing Summary Dose 200-1000 mcg/day Route Intranasal Frequency 1-2x daily Duration 14-30 day cycles ### Beginner Protocol ### Intermediate Protocol ### Advanced Protocol ### Stacking Notes ### Additional Dosage Notes [Full Semax P-21 Dosing Guide](/guides/dosage/semax-p21) [Open Reconstitution Calculator](/tools/reconstitution) ### Unlock Dosing Protocols Free account gets you: - View beginner, intermediate & advanced protocols - See weight-based dosing calculations - Access cycle length & frequency data [Create free account](/auth)[Sign in](/auth) Join other researchers already signed up ## Research [1 PubMed Results](https://pubmed.ncbi.nlm.nih.gov/?term=Semax%20P-21) ### Key Research Findings No clinical or preclinical study of the "Semax P-21" combination exists - it is a speculative stack of two separate peptides. The evidence base for each constituent differs sharply. Semax (an ACTH(4-7) analog) has decades of Russian clinical use and regulatory registration for stroke and cognitive indications (Russian-language literature). P-21 / P021 has been studied only in cell cultures and rodent models of Alzheimer's disease, where chronic oral treatment increased BDNF, enhanced neurogenesis and synaptic plasticity, and reduced tau hyperphosphorylation via decreased GSK-3-beta activity (animal data only; PMID: 27400746, PMID: 25046994). There are no human trials of P021, and none of the combination. Treat all combination claims as research-use-only extrapolation. [Browse Studies on PubMed](https://pubmed.ncbi.nlm.nih.gov/?term=Semax%20P-21) ### Unlock Research Data Free account gets you: - Browse PubMed study summaries - See clinical trial phases & results - Access mechanism of action details [Create free account](/auth)[Sign in](/auth) Join other researchers already signed up ## Interactions Interaction and contraindication data is being compiled for Semax P-21. Check back soon. General Safety Note Always consult a qualified healthcare professional before combining research compounds. Interactions may exist that are not yet documented. [Sign in for alerts ](/auth) No listings found for Semax P-21. Get Semax P-21 Price Drop Alerts Set a target price and we'll notify you when any vendor drops below it. [Sign in to set alerts](/auth) ### Sign in to leave a review Reviews on BodyHackGuide are tied to verified user accounts and moderated before publishing. Sign in (free, no spam) to share your experience with Semax P-21. [Sign in](/auth) ### Related Compounds [View All](/wiki) [ ### Adalank Nootropic Peptide Preclinical / Research compound Adalank is a hybrid research peptide combining structural elements of Adamax (the adamantyl-modified Semax analog) and Selank (the anxiolytic Pro-Gly-Pro tuftsin analog). t½ The commonly cited ~72-hour "functional duration" is an unverified community/vendor claim, not a measured value - no pharmacokinetic study of Adalank has ever been run. The figure is extrapolated from parent Adamax marketing claims. Actual serum half-life is unknown; there is no published PK data. 200-1200 mcg per dose (intranasal or subcutaneous), 1-2x daily Preclinical View Profile ](/compound/adalank)[ ### Adamax Nootropic Peptide Preclinical / Research compound Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. t½ No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. 500-2000 mcg subcutaneous (community research dosing) Preclinical View Profile ](/compound/adamax)[ ### Cerebrolysin Nootropic Peptide Clinical Cerebrolysin is a porcine brain-derived peptide complex developed by EVER Neuro Pharma (Austria) — a low-molecular-weight neurotrophic preparation containing a mixture of free amino acids and bioactive peptides extracted from purified pig brain proteins. t½ ~2-4 hours (multi-component peptide mix) 85 PubMed View Profile ](/compound/cerebrolysin)[ ### Cortexin Nootropic Peptide Marketed in Russia/CIS (Geropharm); human clinical use with limited-quality evidence (small, mostly Russian-language studies; no Western RCT; not FDA/EMA approved) Cortexin is a purified peptide preparation extracted from cattle and pig cerebral cortex tissue — a low-molecular-weight neuropeptide complex used clinically in Russia and Eastern Europe for cognitive impairment, post-stroke recovery, encephalopathy, attention disorders, and pediatric developmental conditions. Like Cerebrolysin, Cortexin is positioned as a broad-spectrum neurotrophic preparation supplying bioactive peptides that mimic endogenous neurotrophic factors. t½ ~2-3 hours (estimated from analog peptide preparations) 18 PubMed View Profile ](/compound/cortexin)[ ### NA-Semax Nootropic Peptide Preclinical NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. t½ ~20-30 minutes (intranasal, estimated from analog data) 3 PubMed View Profile ](/compound/na-semax)[ ### NA-Semax Amidate Nootropic Peptide Preclinical NA-Semax Amidate is the C-terminally amidated NA-Semax — the carboxylic acid at the peptide's C-terminus is replaced with an amide group (-NH2), which is reported to further extend metabolic half-life by resisting carboxypeptidase cleavage in addition to the aminopeptidase resistance the N-acetyl group already provides. The practical effect is a peptide with dosing-frequency use: where standard Semax often requires 3-4 daily doses to maintain effect, NA-Semax Amidate is reported (in vendor monographs and community usage) to maintain subjective effects on a 1-2x daily schedule. t½ ~30-45 minutes (estimated, longer than standard Semax) 2 PubMed View Profile ](/compound/na-semax-amidate) [ View Full Dosage Guide → Protocols, calculator & safety for Semax P-21 ](/guides/dosage/semax-p21) ### Research Score 60 1 PubMed results ### Quality Indicators Data Completeness 75% Description Mechanism of Action Chemical Data Dosing Protocols Safety Profile PubMed Results Interactions Vendor Listings Research Volume 1 PubMed results Limited research available ### Quick Facts Half-Life No combined-product pharmacokinetics exist. Semax (intranasal): the intact peptide is rapidly metabolized (on the order of minutes), though downstream BDNF/neurotrophic effects outlast the peptide itself. P-21 / P021: a small molecule with pharmacokinetics suitable for oral dosing in animal studies; no human PK data. Molecular Weight Not a single molecule - "Semax P-21" is two separate peptides, so no combined molecular weight applies. Per constituent: Semax (heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro) is approximately 813.9 g/mol; P-21 / P021 (Ac-DGGL(A)G-NH2, a CNTF-derived peptide mimetic) is a low-molecular-weight, blood-brain-barrier-permeable small molecule. Trial Phase Preclinical ### Safety Profile Low Risk Common Side Effects - • Mild nasal irritation - • Brief alertness spike Stop Use If - Pregnancy/lactation - Active mania - Peptide allergy [Full Dosage Guide](/guides/dosage/semax-p21)[Calculate Your Dose](/tools/reconstitution) Research Disclaimer This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use. ## Frequently Asked Questions What is Semax P-21 used for in research? Semax P-21 is a **hybrid synthetic peptide** combining structural motifs from [Semax](/compound/semax) and [P-21](/compound/p21) into a single molecule. Marketed as a one-shot drop-in for users running both compounds, the rationale is convenience (one peptide instead of two) and additive cognitive + anxiolytic effects. The peer-reviewed literature on this specific hybrid is essentially absent — most pharmacological characterization is by analogy to the constituent peptides. Treat it as Semax-equivalent on cognition and P-21-equivalent on anxiolysis until stronger primary data emerges. What forms does Semax P-21 come in? Semax P-21 is available in vials, capsules, and sprays forms. How much does Semax P-21 cost? Pricing varies by vendor and form. How do I compare Semax P-21 vendors? Compare prices, payment methods, shipping, and COA scores across 0 vendors. ## Research Tools [ ### Peptide Calculator Reconstitution & syringe units ](/tools/reconstitution)[ ### Reconstitution Guide How to mix, step by step ](/guides/how-to-reconstitute-peptides)[ ### Nasal Spray Calc mL per actuation ](/tools/intranasal)[ ### Half-Life Visualizer Decay curves ](/tools/halflife) ## Related Compounds [View All](/wiki) [ ### Adalank Nootropic Peptide Preclinical / Research compound Adalank is a hybrid research peptide combining structural elements of Adamax (the adamantyl-modified Semax analog) and Selank (the anxiolytic Pro-Gly-Pro tuftsin analog). t½ The commonly cited ~72-hour "functional duration" is an unverified community/vendor claim, not a measured value - no pharmacokinetic study of Adalank has ever been run. The figure is extrapolated from parent Adamax marketing claims. Actual serum half-life is unknown; there is no published PK data. 200-1200 mcg per dose (intranasal or subcutaneous), 1-2x daily Preclinical View Profile ](/compound/adalank)[ ### Adamax Nootropic Peptide Preclinical / Research compound Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. t½ No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. 500-2000 mcg subcutaneous (community research dosing) Preclinical View Profile ](/compound/adamax)[ ### Cerebrolysin Nootropic Peptide Clinical Cerebrolysin is a porcine brain-derived peptide complex developed by EVER Neuro Pharma (Austria) — a low-molecular-weight neurotrophic preparation containing a mixture of free amino acids and bioactive peptides extracted from purified pig brain proteins. t½ ~2-4 hours (multi-component peptide mix) 85 PubMed View Profile ](/compound/cerebrolysin)[ ### Cortexin Nootropic Peptide Marketed in Russia/CIS (Geropharm); human clinical use with limited-quality evidence (small, mostly Russian-language studies; no Western RCT; not FDA/EMA approved) Cortexin is a purified peptide preparation extracted from cattle and pig cerebral cortex tissue — a low-molecular-weight neuropeptide complex used clinically in Russia and Eastern Europe for cognitive impairment, post-stroke recovery, encephalopathy, attention disorders, and pediatric developmental conditions. Like Cerebrolysin, Cortexin is positioned as a broad-spectrum neurotrophic preparation supplying bioactive peptides that mimic endogenous neurotrophic factors. t½ ~2-3 hours (estimated from analog peptide preparations) 18 PubMed View Profile ](/compound/cortexin)[ ### NA-Semax Nootropic Peptide Preclinical NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. t½ ~20-30 minutes (intranasal, estimated from analog data) 3 PubMed View Profile ](/compound/na-semax)[ ### NA-Semax Amidate Nootropic Peptide Preclinical NA-Semax Amidate is the C-terminally amidated NA-Semax — the carboxylic acid at the peptide's C-terminus is replaced with an amide group (-NH2), which is reported to further extend metabolic half-life by resisting carboxypeptidase cleavage in addition to the aminopeptidase resistance the N-acetyl group already provides. The practical effect is a peptide with dosing-frequency use: where standard Semax often requires 3-4 daily doses to maintain effect, NA-Semax Amidate is reported (in vendor monographs and community usage) to maintain subjective effects on a 1-2x daily schedule. t½ ~30-45 minutes (estimated, longer than standard Semax) 2 PubMed View Profile ](/compound/na-semax-amidate) Free 2026 Peptide Cheat Sheet (PDF) Reconstitution math, concentration charts, half-lives, and vendor links. The reference we wish we had on day one. [Download Free](/guides/peptide-cheat-sheet-download?utm_source=compound-semax-p21) ### Need bloodwork before starting? Full hormone + metabolic panels from Anabolic Insights. Code CHONCH for first-order discount. [Order Bloodwork](https://anabolicinsights.ai/?ref=nwm2zjb) ![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. 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