--- title: "NA-Semax: Dosing & Vendor Prices | BodyHackGuide" description: "NA-Semax: dosing protocols, mechanism & side effects, 3 PubMed results. Compare current vendor prices." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compounds", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "NA-Semax" } ] }, { "@context": "https://schema.org", "@type": "MedicalWebPage", "name": "NA-Semax", "description": "NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. The aspartate addition at the N-terminus is reported to improve metabolic stability against aminopeptidase cleavage, extending the in vivo half-life from minutes (parent Semax) to plausibly tens of minutes after intranasal dosing. As of 2026, NA-Semax sits in the same research-peptide tier as standard Semax — it is not FDA-approved for any indication and is sold as a research chemical with limited peer-reviewed primary literature on the acetylated variant specifically. Most published Semax pharmacology applies by analogy, with the caveat that the half-life difference may shift optimal dosing frequency. Reported nonclinical pharmacology mirrors Semax: BDNF upregulation, dopaminergic modulation in mesolimbic circuits, and increased serotonin and dopamine turnover in the cortex and hippocampus. The N-acetyl modification is reported to improve blood-brain-barrier transport, though direct PK comparisons in published literature remain thin.", "lastReviewed": "2026-09-13T18:36:58.638Z", "url": "https://www.bodyhackguide.co/compound/na-semax", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "reviewedBy": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" }, "mainContentOfPage": { "@type": "WebPageElement", "cssSelector": "main" }, "about": { "@type": "Drug", "name": "NA-Semax", "alternateName": [ "N-Acetyl-Semax", "N-acetyl-l-aspartyl-Semax", "NAA-Semax", "Semax NA", "Acetyl Semax" ], "description": "NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. The aspartate addition at the N-terminus is reported to improve metabolic stability against aminopeptidase cleavage, extending the in vivo half-life from minutes (parent Semax) to plausibly tens of minutes after intranasal dosing. As of 2026, NA-Semax sits in the same research-peptide tier as standard Semax — it is not FDA-approved for any indication and is sold as a research chemical with limited peer-reviewed primary literature on the acetylated variant specifically. Most published Semax pharmacology applies by analogy, with the caveat that the half-life difference may shift optimal dosing frequency. Reported nonclinical pharmacology mirrors Semax: BDNF upregulation, dopaminergic modulation in mesolimbic circuits, and increased serotonin and dopamine turnover in the cortex and hippocampus. The N-acetyl modification is reported to improve blood-brain-barrier transport, though direct PK comparisons in published literature remain thin.", "activeIngredient": "NA-Semax", "mechanismOfAction": "Mechanism of action - pharmacological summary (research-use-only): Almost all mechanistic data come from the parent peptide Semax (Met-Glu-His-Phe-Pro-Gly-Pro); the N-acetylated analogue has no dedicated published pharmacology of its own, so the profile below is inferred from Semax, with N-terminal acetylation added for enzymatic stability. BDNF / neurotrophin modulation - parent Semax is reported to raise brain-derived neurotrophic factor and related neurotrophins (NGF, NT-3) and their receptors in cortex and hippocampus, a neuroplasticity pathway characterized mainly in rodent ischemia models (Stavchansky 2011, PMID 22295573). Benefits for human cognition or mood have not been demonstrated in controlled trials. Monoaminergic modulation - Semax raises striatal serotonin turnover (5-HIAA) and potentiates amphetamine-evoked dopamine release, but does not raise baseline dopamine on its own (Eremin 2005, PMID 16362768). There is no published evidence for D2-receptor sensitization or a discrete VTANAc \"drive\" circuit. Anti-inflammatory - in rat cerebral ischemia-reperfusion, Semax blunts the ischemia-induced rise in proinflammatory transcripts including Il1a, Il1b and Il6 plus the chemokines Ccl3/Cxcl2; TNF- message was expressed too weakly to quantify in that study (Dergunova 2021, PMID 34097675). Aminopeptidase resistance - N-terminal acetylation is expected to slow aminopeptidase cleavage and extend in-vivo persistence versus unmodified Semax, but no published head-to-head pharmacokinetic comparison exists, so the magnitude is unverified.", "legalStatus": "Not approved for human use — research chemical", "warning": "For research purposes only. Not for human consumption." } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is NA-Semax used for in research?", "acceptedAnswer": { "@type": "Answer", "text": "NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. The aspartate addition at the N-terminus is reported to improve metabolic stability against aminopeptidase cleavage, extending the in vivo half-life from minutes (parent Semax) to plausibly tens of minutes after intranasal dosing. As of 2026, NA-Semax sits in the same research-peptide tier as standard Semax — it is not FDA-approved for any indication and is sold as a research chemical with limited peer-reviewed primary literature on the acetylated variant specifically. Most published Semax pharmacology applies by analogy, with the caveat that the half-life difference may shift optimal dosing frequency. Reported nonclinical pharmacology mirrors Semax: BDNF upregulation, dopaminergic modulation in mesolimbic circuits, and increased serotonin and dopamine turnover in the cortex and hippocampus. The N-acetyl modification is reported to improve blood-brain-barrier transport, though direct PK comparisons in published literature remain thin." } }, { "@type": "Question", "name": "What forms does NA-Semax come in?", "acceptedAnswer": { "@type": "Answer", "text": "NA-Semax is available in vials, capsules, and sprays forms." } }, { "@type": "Question", "name": "How much does NA-Semax cost?", "acceptedAnswer": { "@type": "Answer", "text": "Pricing varies by vendor and form." } }, { "@type": "Question", "name": "How do I compare NA-Semax vendors?", "acceptedAnswer": { "@type": "Answer", "text": "Compare prices, payment methods, shipping, and COA scores across 0 vendors." } } ] }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompound%2Fna-semax) 100K+ researchers trust BodyHackGuide. Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 3. [Compounds](/compare) 5. NA-Semax [🛒 Where to buy NA-Semax](/buy/na-semax)[🏷️ NA-Semax coupon codes](/coupons/na-semax)[📋 NA-Semax protocol](/protocol/na-semax)[🔄 Alternatives to NA-Semax](/alternatives-to/na-semax)[⚠️ NA-Semax side effects](/side-effects/na-semax) 1. [Home](/) 3. [Compounds](/compare) 5. NA-Semax # NA-Semax Nootropic Peptide Preclinical Download PDF Also known as: N-Acetyl-Semax, N-acetyl-l-aspartyl-Semax, NAA-Semax, Semax NA, Acetyl Semax NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. The aspartate addition at the N-terminus is reported to improve metabolic stability against aminopeptidase cleavage, extending the in vivo half-life from minutes (parent Semax) to plausibly tens of minutes after intranasal dosing. As of 2026, NA-Semax sits in the same research-peptide tier as standard Semax — it is not FDA-approved for any indication and is sold as a research chemical with limited peer-reviewed primary literature on the acetylated variant specifically. Half-Life: ~20-30 minutes (intranasal, estimated from analog data) MW: ~856.0 g/mol (C39H53N9O11S) [3 PubMed Results](https://pubmed.ncbi.nlm.nih.gov/?term=NA-Semax) Last reviewed: Sep 13, 2026 [ 3 PubMed Results ](https://pubmed.ncbi.nlm.nih.gov/?term=NA-Semax)[ Nootropic Peptide Category ](/wiki#cat-nootropic-peptide) Preclinical Research Stage OverviewChemical InfoDosing & ProtocolsInteractionsResearchCompare PricesRelated ## Overview ### At A Glance Mechanism Mechanism of action - pharmacological summary (research-use-only):… Half-Life ~20-30 minutes (intranasal, estimated from analog data) Safety Notes Common Mild nasal irritation Brief alertness spike ### Mechanism of Action **Mechanism of action - pharmacological summary (research-use-only):** Almost all mechanistic data come from the parent peptide Semax (Met-Glu-His-Phe-Pro-Gly-Pro); the N-acetylated analogue has no dedicated published pharmacology of its own, so the profile below is inferred from Semax, with N-terminal acetylation added for enzymatic stability. - **BDNF / neurotrophin modulation** - parent Semax is reported to raise brain-derived neurotrophic factor and related neurotrophins (NGF, NT-3) and their receptors in cortex and hippocampus, a neuroplasticity pathway characterized mainly in rodent ischemia models (Stavchansky 2011, PMID 22295573). Benefits for human cognition or mood have not been demonstrated in controlled trials. - **Monoaminergic modulation** - Semax raises striatal serotonin turnover (5-HIAA) and potentiates amphetamine-evoked dopamine release, but does not raise baseline dopamine on its own (Eremin 2005, PMID 16362768). There is no published evidence for D2-receptor sensitization or a discrete VTANAc "drive" circuit. - **Anti-inflammatory** - in rat cerebral ischemia-reperfusion, Semax blunts the ischemia-induced rise in proinflammatory transcripts including Il1a, Il1b and Il6 plus the chemokines Ccl3/Cxcl2; TNF- message was expressed too weakly to quantify in that study (Dergunova 2021, PMID 34097675). - **Aminopeptidase resistance** - N-terminal acetylation is expected to slow aminopeptidase cleavage and extend in-vivo persistence versus unmodified Semax, but no published head-to-head pharmacokinetic comparison exists, so the magnitude is unverified. ### Overview NA-Semax is the **N-acetyl-l-aspartyl variant of [Semax](/compound/semax)** — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. The aspartate addition at the N-terminus is reported to improve metabolic stability against aminopeptidase cleavage, extending the in vivo half-life from minutes (parent Semax) to plausibly tens of minutes after intranasal dosing. As of 2026, NA-Semax sits in the same research-peptide tier as standard Semax — it is **not FDA-approved** for any indication and is sold as a research chemical with limited peer-reviewed primary literature on the acetylated variant specifically. Most published Semax pharmacology applies by analogy, with the caveat that the half-life difference may shift optimal dosing frequency. Reported nonclinical pharmacology mirrors Semax: BDNF upregulation, dopaminergic modulation in mesolimbic circuits, and increased serotonin and dopamine turnover in the cortex and hippocampus. The N-acetyl modification is reported to improve blood-brain-barrier transport, though direct PK comparisons in published literature remain thin. ## Chemical Information IUPAC Name Not yet available CAS Number Not yet available Molecular Formula C40H56N12O11 Molecular Mass ~856.0 g/mol (C39H53N9O11S) Amino Acid Sequence Ac-Met-Glu-His-Phe-Pro-Gly-Pro (Ac-MEHFPGP) ## Dosing & Protocols ### Dosing Summary Dose 200-1000 mcg/day Route Intranasal Frequency 1-3x daily Duration 14-30 day cycles ### Beginner Protocol ### Intermediate Protocol ### Advanced Protocol ### Stacking Notes [Full NA-Semax Dosing Guide](/guides/dosage/na-semax) [Open Reconstitution Calculator](/tools/reconstitution) ### Unlock Dosing Protocols Free account gets you: - View beginner, intermediate & advanced protocols - See weight-based dosing calculations - Access cycle length & frequency data [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Research [3 PubMed Results](https://pubmed.ncbi.nlm.nih.gov/?term=NA-Semax) ### Safety & Side Effects **No controlled human safety data exist for N-acetyl-Semax.** It is an unapproved research peptide; the notes below are anecdotal (user-reported) or extrapolated from intranasal parent Semax and should not be read as an established safety profile. Reported frequencies are unknown. - **Nasal / local irritation** - stinging, dryness, or mild congestion after intranasal spray; the most commonly reported effect. - **Headache** - transient and usually mild; reported more often at higher or late-day dosing. - **Irritability, overstimulation, or restlessness** - occasionally reported, consistent with an activating/stimulating peptide. - **Sleep disruption** - reported when dosed later in the day. Because no formal toxicology or human trials have been published for the acetylated analogue, unexpected or idiosyncratic reactions cannot be excluded. For research use only; not for human or veterinary consumption. [Browse Studies on PubMed](https://pubmed.ncbi.nlm.nih.gov/?term=NA-Semax) ### Unlock Research Data Free account gets you: - Browse PubMed study summaries - See clinical trial phases & results - Access mechanism of action details [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Interactions ### Contraindications **Research-use-only; not for human or veterinary use.** No formal contraindication data exist for N-acetyl-Semax. As a precaution, this compound should not be used by: - Pregnant or breastfeeding individuals (no reproductive or developmental safety data). - Anyone with a known hypersensitivity to Semax, ACTH(4-10)-fragment peptides, or product excipients. - People with active psychiatric instability (e.g., mania or psychosis) or poorly controlled anxiety, given the activating/stimulatory profile of the parent peptide. - Anyone with significant nasal or sinus pathology if using the intranasal route. No human drug-interaction studies have been performed. The monoaminergic activity seen with parent Semax - potentiation of amphetamine-evoked dopamine release (Eremin 2005, PMID 16362768) - is a theoretical basis for caution when combined with stimulants or other monoaminergic/serotonergic agents. Research Disclaimer This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds. [Sign in for alerts ](/auth) No listings found for NA-Semax. Get NA-Semax Price Drop Alerts Set a target price and we'll notify you when any vendor drops below it. [Sign in to set alerts](/auth) ### Sign in to leave a review Reviews on BodyHackGuide are tied to verified user accounts and moderated before publishing. Sign in (free, no spam) to share your experience with NA-Semax. [Sign in](/auth) ### Related Compounds [View All](/wiki) [ ### Adalank Nootropic Peptide Preclinical / Research compound Adalank is a hybrid research peptide combining structural elements of Adamax (the adamantyl-modified Semax analog) and Selank (the anxiolytic Pro-Gly-Pro tuftsin analog). t½ The commonly cited ~72-hour "functional duration" is an unverified community/vendor claim, not a measured value - no pharmacokinetic study of Adalank has ever been run. The figure is extrapolated from parent Adamax marketing claims. Actual serum half-life is unknown; there is no published PK data. 200-1200 mcg per dose (intranasal or subcutaneous), 1-2x daily Preclinical View Profile ](/compound/adalank)[ ### Adamax Nootropic Peptide Preclinical / Research compound Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. t½ No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. 500-2000 mcg subcutaneous (community research dosing) Preclinical View Profile ](/compound/adamax)[ ### Cerebrolysin Nootropic Peptide Clinical Cerebrolysin is a porcine brain-derived peptide complex developed by EVER Neuro Pharma (Austria) — a low-molecular-weight neurotrophic preparation containing a mixture of free amino acids and bioactive peptides extracted from purified pig brain proteins. t½ ~2-4 hours (multi-component peptide mix) 85 PubMed View Profile ](/compound/cerebrolysin)[ ### Cortexin Nootropic Peptide Marketed in Russia/CIS (Geropharm); human clinical use with limited-quality evidence (small, mostly Russian-language studies; no Western RCT; not FDA/EMA approved) Cortexin is a purified peptide preparation extracted from cattle and pig cerebral cortex tissue — a low-molecular-weight neuropeptide complex used clinically in Russia and Eastern Europe for cognitive impairment, post-stroke recovery, encephalopathy, attention disorders, and pediatric developmental conditions. Like Cerebrolysin, Cortexin is positioned as a broad-spectrum neurotrophic preparation supplying bioactive peptides that mimic endogenous neurotrophic factors. t½ ~2-3 hours (estimated from analog peptide preparations) 18 PubMed View Profile ](/compound/cortexin)[ ### NA-Semax Amidate Nootropic Peptide Preclinical NA-Semax Amidate is the C-terminally amidated NA-Semax — the carboxylic acid at the peptide's C-terminus is replaced with an amide group (-NH2), which is reported to further extend metabolic half-life by resisting carboxypeptidase cleavage in addition to the aminopeptidase resistance the N-acetyl group already provides. The practical effect is a peptide with dosing-frequency use: where standard Semax often requires 3-4 daily doses to maintain effect, NA-Semax Amidate is reported (in vendor monographs and community usage) to maintain subjective effects on a 1-2x daily schedule. t½ ~30-45 minutes (estimated, longer than standard Semax) 2 PubMed View Profile ](/compound/na-semax-amidate)[ ### P-21 Nootropic Peptide Preclinical P-21 is a synthetic cyclic dipeptide — Cyclo(L-prolyl-glycine) — derived from the Selank/Semax C-terminal Pro-Gly-Pro motif. t½ Not formally characterized in published work. P021 has only been studied in rodents (oral/dietary and subcutaneous dosing); no human pharmacokinetic data exist. 4 PubMed View Profile ](/compound/p21) [ View Full Dosage Guide → Protocols, calculator & safety for NA-Semax ](/guides/dosage/na-semax) ### Related Articles [All Posts](/blog) [ #### The Best Peptide Nasal Sprays of 2026, Ranked by Evidence An evidence-tiered review of 10 peptide nasal sprays. S tier: Semax, Selank, oxytocin. A tier: PT-141, DSIP, Epithalon. B tier: Noopept, NAD+, 5-Amino-1MQ. C tier: Melanotan-II. It covers human-trial counts, PMID citations, safety, and pre-made vs DIY tradeoffs. 4/21/2026 ](/blog/best-peptide-nasal-sprays-2026) ### Research Score 60 3 PubMed results ### Quality Indicators Data Completeness 75% Description Mechanism of Action Chemical Data Dosing Protocols Safety Profile PubMed Results Interactions Vendor Listings Research Volume 3 PubMed results Limited research available ### Quick Facts Half-Life ~20-30 minutes (intranasal, estimated from analog data) Molecular Weight ~856.0 g/mol (C39H53N9O11S) Trial Phase Preclinical ### Safety Profile Low Risk Common Side Effects - • Mild nasal irritation - • Brief alertness spike Stop Use If - Pregnancy/lactation - Active mania - Known peptide allergy [Full Dosage Guide](/guides/dosage/na-semax)[Calculate Your Dose](/tools/reconstitution) Research Disclaimer This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use. ## Frequently Asked Questions What is NA-Semax used for in research? NA-Semax is the **N-acetyl-l-aspartyl variant of [Semax](/compound/semax)** — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. The aspartate addition at the N-terminus is reported to improve metabolic stability against aminopeptidase cleavage, extending the in vivo half-life from minutes (parent Semax) to plausibly tens of minutes after intranasal dosing. As of 2026, NA-Semax sits in the same research-peptide tier as standard Semax — it is **not FDA-approved** for any indication and is sold as a research chemical with limited peer-reviewed primary literature on the acetylated variant specifically. Most published Semax pharmacology applies by analogy, with the caveat that the half-life difference may shift optimal dosing frequency. Reported nonclinical pharmacology mirrors Semax: BDNF upregulation, dopaminergic modulation in mesolimbic circuits, and increased serotonin and dopamine turnover in the cortex and hippocampus. The N-acetyl modification is reported to improve blood-brain-barrier transport, though direct PK comparisons in published literature remain thin. What forms does NA-Semax come in? NA-Semax is available in vials, capsules, and sprays forms. How much does NA-Semax cost? Pricing varies by vendor and form. How do I compare NA-Semax vendors? Compare prices, payment methods, shipping, and COA scores across 0 vendors. ## Research Tools [ ### Peptide Calculator Reconstitution & syringe units ](/tools/reconstitution)[ ### Reconstitution Guide How to mix, step by step ](/guides/how-to-reconstitute-peptides)[ ### Nasal Spray Calc mL per actuation ](/tools/intranasal)[ ### Half-Life Visualizer Decay curves ](/tools/halflife) ## Related Compounds [View All](/wiki) [ ### Adalank Nootropic Peptide Preclinical / Research compound Adalank is a hybrid research peptide combining structural elements of Adamax (the adamantyl-modified Semax analog) and Selank (the anxiolytic Pro-Gly-Pro tuftsin analog). t½ The commonly cited ~72-hour "functional duration" is an unverified community/vendor claim, not a measured value - no pharmacokinetic study of Adalank has ever been run. The figure is extrapolated from parent Adamax marketing claims. Actual serum half-life is unknown; there is no published PK data. 200-1200 mcg per dose (intranasal or subcutaneous), 1-2x daily Preclinical View Profile ](/compound/adalank)[ ### Adamax Nootropic Peptide Preclinical / Research compound Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. t½ No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. 500-2000 mcg subcutaneous (community research dosing) Preclinical View Profile ](/compound/adamax)[ ### Cerebrolysin Nootropic Peptide Clinical Cerebrolysin is a porcine brain-derived peptide complex developed by EVER Neuro Pharma (Austria) — a low-molecular-weight neurotrophic preparation containing a mixture of free amino acids and bioactive peptides extracted from purified pig brain proteins. t½ ~2-4 hours (multi-component peptide mix) 85 PubMed View Profile ](/compound/cerebrolysin)[ ### Cortexin Nootropic Peptide Marketed in Russia/CIS (Geropharm); human clinical use with limited-quality evidence (small, mostly Russian-language studies; no Western RCT; not FDA/EMA approved) Cortexin is a purified peptide preparation extracted from cattle and pig cerebral cortex tissue — a low-molecular-weight neuropeptide complex used clinically in Russia and Eastern Europe for cognitive impairment, post-stroke recovery, encephalopathy, attention disorders, and pediatric developmental conditions. Like Cerebrolysin, Cortexin is positioned as a broad-spectrum neurotrophic preparation supplying bioactive peptides that mimic endogenous neurotrophic factors. t½ ~2-3 hours (estimated from analog peptide preparations) 18 PubMed View Profile ](/compound/cortexin)[ ### NA-Semax Amidate Nootropic Peptide Preclinical NA-Semax Amidate is the C-terminally amidated NA-Semax — the carboxylic acid at the peptide's C-terminus is replaced with an amide group (-NH2), which is reported to further extend metabolic half-life by resisting carboxypeptidase cleavage in addition to the aminopeptidase resistance the N-acetyl group already provides. The practical effect is a peptide with dosing-frequency use: where standard Semax often requires 3-4 daily doses to maintain effect, NA-Semax Amidate is reported (in vendor monographs and community usage) to maintain subjective effects on a 1-2x daily schedule. t½ ~30-45 minutes (estimated, longer than standard Semax) 2 PubMed View Profile ](/compound/na-semax-amidate)[ ### P-21 Nootropic Peptide Preclinical P-21 is a synthetic cyclic dipeptide — Cyclo(L-prolyl-glycine) — derived from the Selank/Semax C-terminal Pro-Gly-Pro motif. t½ Not formally characterized in published work. P021 has only been studied in rodents (oral/dietary and subcutaneous dosing); no human pharmacokinetic data exist. 4 PubMed View Profile ](/compound/p21) Free 2026 Peptide Cheat Sheet — 50 pages, PDF Reconstitution math, concentration charts, half-lives, and vendor trust tiers. The reference we wish we had on day one. 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