--- title: "N-Acetyl-Selank: Dosing & Vendor Prices | BodyHackGuide" url: https://www.bodyhackguide.co/compound/n-acetyl-selank description: "N-Acetyl-Selank: dosing protocols, mechanism & side effects. Compare 1 current vendor prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # N-Acetyl-Selank Cognitive (https://www.bodyhackguide.co/wiki#cat-cognitive)Preclinical (the N-acetyl analog has no dedicated studies); parent Selank has limited clinical use in Russia Also known as: NASA-Selank, N-Acetyl Selank N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a tuftsin-derived heptapeptide used intranasally for its reported anxiolytic and nootropic effects. The acetyl group is claimed to improve stability and duration versus standard Selank, though the analog itself is essentially unstudied. Image: Disguised Alpha logo (https://disguisedalpha.com/wp-content/themes/assets/logos/disguised-logo-2x.png) Lowest price per mg $2.67/mg $79.99 for 30mg at Disguised Alpha Buy at Disguised Alpha: https://disguisedalpha.com/product/n-acetyl-selank-amidate/?coupon=reddit Half-life: Not established for the N-acetyl analog MW: ~793.9 g/mol (theoretical: Selank ~751.9 g/mol + N-terminal a… Last reviewed: Oct 2, 2026 ## Overview ### At A Glance Mechanism N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunopeptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro tail added to slow enzymatic breakdown. Because published phar… Half-Life Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature. Dosing Once or twice daily (intranasal); some advanced users split into 2-3 doses Dose Range 100-900 mcg Potential Benefits Anxiolytic (calming) effects - the most-studied action of parent Selank, including a Russian clinical trial in generalized anxiety disorder [PMID:18454096] Nootropic / cognitive support - reported attention and memory benefits in rodent models, linked to BDNF changes [PMID:31625062] Stress resilience reported without the sedation, tolerance, or dependence typically seen with benzodiazepines (preclinical framing) [PMID:30255741] Possible support during withdrawal states (alcohol, opioid) in animal models [PMID:24913576][PMID:36322304] Claimed longer duration vs. plain Selank from N-terminal acetylation - a community/vendor claim not verified in published data ### Mechanism of Action N-Acetyl-Selank is the N-terminally acetylated analog of Selank (https://www.bodyhackguide.co/compound/selank), a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunopeptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro tail added to slow enzymatic breakdown. Because published pharmacology exists only for Selank itself, the mechanisms below are inherited from the parent peptide; the acetyl modification is discussed separately. Parent Selank mechanisms (preclinical and limited clinical work): - GABAergic modulation: acts as a subtype-selective positive allosteric modulator of GABA-A receptor binding, proposed to underlie its benzodiazepine-like anxiolytic effect without classic sedation or dependence [PMID:30255741]. - Enkephalin/opioid system: raises the half-life of leu-enkephalin (slows its degradation), and its anxiolytic sensitivity is opioid-dependent, pointing to modulation of the enkephalinergic system [PMID:18454096][PMID:22550852]. - Neurotrophic signaling: normalizes brain-derived neurotrophic factor (BDNF) in the hippocampus and prefrontal cortex in rodent models [PMID:31625062]. - Route-dependent receptor effects: intranasal vs. intraperitoneal dosing shifts the balance between GABA and NMDA receptor binding, consistent with formation of active fragments [PMID:29787664]. The acetyl group: N-terminal acetylation is used (as with N-Acetyl-Semax) to blunt aminopeptidase cleavage of the exposed N-terminus, which vendors and users claim extends stability and duration of action. This specific claim has not been tested for Selank in any published study, so treat it as a plausible chemistry-based rationale rather than a demonstrated fact. ### Overview N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a tuftsin-derived heptapeptide used intranasally for its reported anxiolytic and nootropic effects. The acetyl group is claimed to improve stability and duration versus standard Selank, though the analog itself is essentially unstudied. Research use only (RUO). ### What to Expect - • Subtle, non-sedating calm rather than a strong acute effect; parent Selank is described as a 'mild' anxiolytic [PMID:30255741]. - • Community users of the acetyl analog report calm focus and reduced stress reactivity, often within 15-40 minutes of an intranasal dose (anecdotal). - • Any claimed longer duration from acetylation is not documented in published studies - individual response varies. - • Nootropic/attention benefits, where reported, tend to be modest and build over a multi-day course rather than from a single dose [PMID:31625062]. Individual responses vary. Timeline based on commonly reported research observations. ## Chemical Information IUPAC Name Not yet available CAS Number Not yet available Molecular Formula Not yet available Molecular Mass ~793.9 g/mol (theoretical: Selank ~751.9 g/mol + N-terminal acetyl, ~+42). Approximate molecular formula C35H59N11O10. Amino Acid Sequence Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro (N-acetyl-TKPRPGP) - the acetyl group caps the N-terminal threonine of the Selank heptapeptide. ## Dosing & Protocols ### Unlock the dosing protocols Enter your email to keep reading. It is free, and it opens these tabs on every compound page in this browser. - Dose, route and how often - Beginner, intermediate and advanced protocols - Additional dosage notes You also get the free peptide cheat sheet by email. Unsubscribe anytime. Have an account? Sign in (https://www.bodyhackguide.co/auth) ## Research ### Unlock the research summary - A summary of the key research - Safety and side effects - A link to the PubMed results ## Interactions ### Interaction Matrix ### Contraindications Pregnancy and breastfeeding (untested). Known hypersensitivity to the peptide. Use caution - ideally under professional guidance - if combining with benzodiazepines, other GABAergic agents, opioids, or alcohol, because parent Selank modulates GABA/enkephalin signaling and potentiated diazepam in animal models [PMID:28280289][PMID:22550852]. Not a substitute for prescribed treatment of an anxiety disorder. Research use only; not for human consumption where prohibited. Research Disclaimer This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds. Best Price $79.99 Best $/mg $2.6663 Vendors 1 Listings 2 vial, nasal Form Sort | Vendor | Product | Form | Qty | Price | $/mg | Coupon | | | --- | --- | --- | --- | --- | --- | --- | --- | | Image: Disguised Alpha logo (https://disguisedalpha.com/wp-content/themes/assets/logos/disguised-logo-2x.png) Disguised Alpha (https://www.bodyhackguide.co/vendors/disguised-alpha) 50: https://www.bodyhackguide.co/vendor-trust-scorecard 🇺🇸 US 🇪🇺 EU 🇬🇧 UK | NA-Selank Amidate 30 mg (sold as Adalank) | vial | 1 vial ● In Stock | $79.99 BEST | $2.67 | — | Buy: https://disguisedalpha.com/product/n-acetyl-selank-amidate/?coupon=reddit | | Image: Disguised Alpha logo (https://disguisedalpha.com/wp-content/themes/assets/logos/disguised-logo-2x.png) Disguised Alpha (https://www.bodyhackguide.co/vendors/disguised-alpha) 50: https://www.bodyhackguide.co/vendor-trust-scorecard 🇺🇸 US 🇪🇺 EU 🇬🇧 UK | NA-Selank Amidate Aerosol Spray (sold as Adalank) | nasal | 10 mL spray ● In Stock | $79.99 | — | — | Buy: https://disguisedalpha.com/product/adalank-aerosol-spray/?coupon=reddit | ### Sign in to leave a review Reviews on BodyHackGuide are tied to verified user accounts and moderated before publishing. Sign in (free, no spam) to share your experience with N-Acetyl-Selank. Current low $79.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet Tracking since Sep 5, 2026 · 2 data points ### Vendors Selling N-Acetyl-Selank #### Disguised Alpha 2 listings · from $79.99 https://www.bodyhackguide.co/vendors/disguised-alpha How we score these vendors Every supplier above is graded 0 to 100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank. View Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ### Related Compounds View All (https://www.bodyhackguide.co/wiki) ### N-Acetyl-Semax Cognitive Duplicate entry - see NA-Semax This is a duplicate/alias entry. Preclinical View Profile https://www.bodyhackguide.co/compound/n-acetyl-semax ### Noopept + Choline Chloride Blend Cognitive Blend has no clinical trials; component evidence ranges from preclinical (Noopept) to small human RCTs (choline sources). A community nootropic stack pairing Noopept, a potent racetam-family dipeptide, with a choline source (commonly alpha-GPC, CDP-choline/citicoline, or choline bitartrate). t½ Not a single-molecule value - this is a two-component stack. Noopept has a short plasma half-life, with central effects that outlast blood levels; the rise in brain choline from alpha-GPC or CDP-choline persists for several hours. Noopept 10-30 mg (10,000-30,000 mcg)/day; choline source 150-600 mg/day (alpha-GPC) or 250-500 mg/day (CDP-choline). The blend has no validated dosing - ranges are extrapolated from single-component use. Preclinical View Profile https://www.bodyhackguide.co/compound/noopept-choline-blend ### Side-by-Side Comparisons All Comparisons (https://www.bodyhackguide.co/compare) N-Acetyl-Selank vs N-Acetyl-Semax: https://www.bodyhackguide.co/compare/n-acetyl-selank-vs-n-acetyl-semax View Full Dosage Guide → Protocols, calculator & safety for N-Acetyl-Selank https://www.bodyhackguide.co/guides/dosage/n-acetyl-selank ### Lowest Price per mg Disguised Alpha $79.99($2.67/mg) 1 vendor · 2 listings ### Research Score 45 0 PubMed results ### Quality Indicators Data Completeness 75% Description Mechanism of Action Chemical Data Dosing Protocols Safety Profile PubMed Results Interactions Vendor Listings ### Quick Facts Half-Life Molecular Weight Trial Phase Preclinical (the N-acetyl analog has no dedicated studies); parent Selank has limited clinical use in Russia 0 Research Disclaimer This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use. ## Frequently Asked Questions What is N-Acetyl-Selank and how is it different from regular Selank? It's Selank (https://www.bodyhackguide.co/compound/selank) (the heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro) with an acetyl group added to the N-terminus. The modification is meant to slow enzymatic breakdown of the peptide's front end - the same trick used for N-Acetyl-Semax - and is claimed to give longer, more stable activity. That claim hasn't been confirmed in any published study on Selank. Does N-Acetyl-Selank actually work better than Selank? There's no head-to-head data. All of the human and animal evidence is for plain Selank; the acetylated version has no dedicated trials. Any 'works better / lasts longer' claims are theoretical or anecdotal, so treat them cautiously. How is it taken? Intranasally, as a nasal spray - it is not injected. Community ranges run roughly 100-900 mcg/day, usually 1-2 sprays, often in 2-4 week courses. There is no clinically established dose for the analog. Research use only. Is it safe? Parent Selank was well tolerated in short Russian trials with no serious side effects reported [PMID:18454096], but the acetyl analog has no safety studies at all. Reported issues are mild (nasal irritation, transient fatigue, headache). Long-term safety is unknown. Can I combine it with other supplements or medications? Be cautious with benzodiazepines, other GABAergic compounds, opioids, and alcohol - parent Selank modulates GABA and enkephalin signaling and potentiated diazepam in animal studies [PMID:28280289]. Talk to a professional before combining, and don't use it as a replacement for prescribed anxiety treatment. Is N-Acetyl-Selank approved or legal? It is not approved by the FDA or EMA. Even standard Selank is a registered medicine only in Russia. N-Acetyl-Selank is sold as a research chemical and is intended for research use only. ## Research Tools ### Peptide Calculator Reconstitution & syringe units https://www.bodyhackguide.co/tools/reconstitution ### Reconstitution Guide How to mix, step by step https://www.bodyhackguide.co/guides/how-to-reconstitute-peptides ### Nasal Spray Calc mL per actuation https://www.bodyhackguide.co/tools/intranasal ### Half-Life Visualizer Decay curves https://www.bodyhackguide.co/tools/halflife ## Related Compounds ### N-Acetyl-Semax This is a duplicate/alias entry. ### Noopept + Choline Chloride Blend ## Side-by-Side Comparisons Compare N-Acetyl-Selank head-to-head: mechanism, half-life, dosing, safety, and vendor prices. Free 2026 Peptide Cheat Sheet (PDF) 38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers. Download Free (https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download) ### Need bloodwork before starting? Full hormone + metabolic panels from Anabolic Insights. Code CHONCH for first-order discount. Image: BodyHackGuide (https://www.bodyhackguide.co/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide #### Explore - Compare prices: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors - Deals: https://www.bodyhackguide.co/deals - Coupons: https://www.bodyhackguide.co/coupons - Nootropics: https://www.bodyhackguide.co/nootropics - Brain health: https://www.bodyhackguide.co/brain-health - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides #### Tools - Reconstitution: https://www.bodyhackguide.co/tools/reconstitution - Half-life visualizer: https://www.bodyhackguide.co/tools/halflife - COA reader: https://www.bodyhackguide.co/tools/coa - Cost calculator: https://www.bodyhackguide.co/tools/cost-calculator - Stack builder: https://www.bodyhackguide.co/stack-builder - All tools: https://www.bodyhackguide.co/tools #### Trust & vendors - Vendor directory: https://www.bodyhackguide.co/vendors - Trust scorecard: https://www.bodyhackguide.co/vendors/scorecard - Vendor trust badge: https://www.bodyhackguide.co/vendors/get-vetted - Scoring methodology: https://www.bodyhackguide.co/vendors/methodology - Peptide cheat sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download #### Company - About: https://www.bodyhackguide.co/about - Affiliate disclosure: https://www.bodyhackguide.co/affiliate-disclosure - Editorial standards: https://www.bodyhackguide.co/editorial-standards - Creators: https://www.bodyhackguide.co/creators - Coaches: https://www.bodyhackguide.co/coaches - 1-on-1 coaching: https://www.bodyhackguide.co/coaching - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Full site directory: https://www.bodyhackguide.co/site-directory **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology), and we earn a commission from purchases made through some of our links at no extra cost to you. 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All rights reserved. · Terms (https://www.bodyhackguide.co/terms) · Privacy (https://www.bodyhackguide.co/privacy) ## Structured data ```json [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compounds", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "N-Acetyl-Selank" } ] }, { "@context": "https://schema.org", "@type": "Product", "name": "N-Acetyl-Selank", "description": "N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a tuftsin-derived heptapeptide used intranasally for its reported anxiolytic and nootropic effects. The acetyl group is claimed to improve stability and duration versus standard Selank, though the analog itself is essentially unstudied. 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The acetyl group is claimed to improve stability and duration versus standard Selank, though the analog itself is essentially unstudied. 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The acetyl group is claimed to improve stability and duration versus standard Selank, though the analog itself is essentially unstudied. Research use only (RUO).", "activeIngredient": "N-Acetyl-Selank", "mechanismOfAction": "N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunopeptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro tail added to slow enzymatic breakdown. Because published pharmacology exists only for Selank itself, the mechanisms below are inherited from the parent peptide; the acetyl modification is discussed separately. Parent Selank mechanisms (preclinical and limited clinical work): GABAergic modulation: acts as a subtype-selective positive allosteric modulator of GABA-A receptor binding, proposed to underlie its benzodiazepine-like anxiolytic effect without classic sedation or dependence [PMID:30255741]. Enkephalin/opioid system: raises the half-life of leu-enkephalin (slows its degradation), and its anxiolytic sensitivity is opioid-dependent, pointing to modulation of the enkephalinergic system PMID:18454096. Neurotrophic signaling: normalizes brain-derived neurotrophic factor (BDNF) in the hippocampus and prefrontal cortex in rodent models [PMID:31625062]. Route-dependent receptor effects: intranasal vs. intraperitoneal dosing shifts the balance between GABA and NMDA receptor binding, consistent with formation of active fragments [PMID:29787664]. The acetyl group: N-terminal acetylation is used (as with N-Acetyl-Semax) to blunt aminopeptidase cleavage of the exposed N-terminus, which vendors and users claim extends stability and duration of action. This specific claim has not been tested for Selank in any published study, so treat it as a plausible chemistry-based rationale rather than a demonstrated fact.", "dosageForm": "vial, nasal", "legalStatus": "Not approved for human use (research chemical)", "warning": "For research purposes only. Not for human consumption." } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is N-Acetyl-Selank and how is it different from regular Selank?", "acceptedAnswer": { "@type": "Answer", "text": "It's Selank (the heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro) with an acetyl group added to the N-terminus. The modification is meant to slow enzymatic breakdown of the peptide's front end - the same trick used for N-Acetyl-Semax - and is claimed to give longer, more stable activity. That claim hasn't been confirmed in any published study on Selank." } }, { "@type": "Question", "name": "Does N-Acetyl-Selank actually work better than Selank?", "acceptedAnswer": { "@type": "Answer", "text": "There's no head-to-head data. All of the human and animal evidence is for plain Selank; the acetylated version has no dedicated trials. Any 'works better / lasts longer' claims are theoretical or anecdotal, so treat them cautiously." } }, { "@type": "Question", "name": "How is it taken?", "acceptedAnswer": { "@type": "Answer", "text": "Intranasally, as a nasal spray - it is not injected. Community ranges run roughly 100-900 mcg/day, usually 1-2 sprays, often in 2-4 week courses. There is no clinically established dose for the analog. Research use only." } }, { "@type": "Question", "name": "Is it safe?", "acceptedAnswer": { "@type": "Answer", "text": "Parent Selank was well tolerated in short Russian trials with no serious side effects reported [PMID:18454096], but the acetyl analog has no safety studies at all. Reported issues are mild (nasal irritation, transient fatigue, headache). Long-term safety is unknown." } }, { "@type": "Question", "name": "Can I combine it with other supplements or medications?", "acceptedAnswer": { "@type": "Answer", "text": "Be cautious with benzodiazepines, other GABAergic compounds, opioids, and alcohol - parent Selank modulates GABA and enkephalin signaling and potentiated diazepam in animal studies [PMID:28280289]. Talk to a professional before combining, and don't use it as a replacement for prescribed anxiety treatment." } }, { "@type": "Question", "name": "Is N-Acetyl-Selank approved or legal?", "acceptedAnswer": { "@type": "Answer", "text": "It is not approved by the FDA or EMA. Even standard Selank is a registered medicine only in Russia. 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