--- title: "HMG (Human Menopausal Gonadotropin): Dosing & Vendor Prices" description: "HMG (Human Menopausal Gonadotropin): dosing protocols, mechanism & side effects. Compare 1 verified vendor prices." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compounds", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "HMG (Human Menopausal Gonadotropin)" } ] }, { "@context": "https://schema.org", "@type": "Product", "name": "HMG (Human Menopausal Gonadotropin)", "description": "HMG, or human menopausal gonadotropin, is not a synthetic research chemical. It is menotropins, an approved injectable fertility drug purified from the urine of postmenopausal women. It is a mixture rather than a single molecule: each vial of the currently marketed US product, Menopur, contains 75 international units of follicle-stimulating hormone activity and 75 international units of luteinizing hormone activity, and human chorionic gonadotropin from the urine source is detected in the product. The initial US approval for menotropins dates to 1975 (Menopur US prescribing information). The two hormones do different jobs. Follicle-stimulating hormone acts on granulosa cells in the ovary and on Sertoli cells in the testis to support gamete development. Luteinizing hormone acts on theca cells and, in men, on Leydig cells to drive steroid production. Giving both together reproduces the pituitary signal that is missing when the hypothalamic-pituitary axis is not working, or supplies a supraphysiological signal to recruit multiple follicles in assisted reproduction. The approved US indication is narrow: development of multiple follicles and pregnancy in ovulatory women as part of an assisted reproductive technology cycle. Older menotropins labeling also carried an indication, with concomitant human chorionic gonadotropin, for stimulating spermatogenesis in men with primary or secondary hypogonadotropic hypogonadism. In current practice, that male use is well documented in the literature even where it is not on the label of the marketed product. A systematic review and meta-analysis of 103 studies covering 5328 male patients with hypogonadotropic hypogonadism found human menopausal gonadotropin used in 40.8 percent of studies, and reported spermatogenesis in 86 percent of patients treated with human chorionic gonadotropin plus follicle-stimulating hormone against 40 percent with human chorionic gonadotropin alone (PMID: 38128110). A retrospective cohort of 122 Chinese men treated with combined human chorionic gonadotropin and human menopausal gonadotropin over 24 months reported spermatogenesis in 92.3 percent of men with partial disease and 74.7 percent of those with complete disease (PMID: 31464203). The safety profile is the reason this is a prescription drug. The label carries warnings for ovarian hyperstimulation syndrome, abnormal ovarian enlargement, pulmonary and vascular complications, ovarian torsion, multi-fetal gestation, congenital malformations, ectopic pregnancy, spontaneous abortion and ovarian neoplasms. In the registration trials the most common adverse reactions included abdominal pain in 6.7 percent, headache in 6.2 percent, ovarian hyperstimulation syndrome in 6.2 percent and injection site reactions in 3.9 percent (Menopur US prescribing information). For male athletes in tested sport, hMG is prohibited. The World Anti-Doping Agency prohibits chorionic gonadotrophin and luteinizing hormone and their releasing factors in male athletes under section S2 of the Prohibited List, and hMG contains luteinizing hormone activity. What is sold outside pharmacy channels as a research-use vial is not the approved product, has no verified potency in international units, and carries the contamination and mislabeling risks common to that market.", "url": "https://www.bodyhackguide.co/compound/hmg", "image": "https://www.bodyhackguide.co/og-image.png", "brand": { "@type": "Brand", "name": "Research Compound" }, "offers": { "@type": "AggregateOffer", "lowPrice": "54.99", "highPrice": "54.99", "priceCurrency": "USD", "offerCount": "1", "availability": "https://schema.org/InStock", "offers": [ { "@type": "Offer", "price": "54.99", "priceCurrency": "USD", "availability": "https://schema.org/InStock", "itemCondition": "https://schema.org/NewCondition", "url": "https://disguisedalpha.com/product/hmg/?coupon=reddit", "seller": { "@type": "Organization", "name": "Disguised Alpha", "url": "https://disguisedalpha.com/?coupon=reddit" } } ] } }, { "@context": "https://schema.org", "@type": "MedicalWebPage", "name": "HMG (Human Menopausal Gonadotropin)", "description": "HMG, or human menopausal gonadotropin, is not a synthetic research chemical. It is menotropins, an approved injectable fertility drug purified from the urine of postmenopausal women. It is a mixture rather than a single molecule: each vial of the currently marketed US product, Menopur, contains 75 international units of follicle-stimulating hormone activity and 75 international units of luteinizing hormone activity, and human chorionic gonadotropin from the urine source is detected in the product. The initial US approval for menotropins dates to 1975 (Menopur US prescribing information). The two hormones do different jobs. Follicle-stimulating hormone acts on granulosa cells in the ovary and on Sertoli cells in the testis to support gamete development. Luteinizing hormone acts on theca cells and, in men, on Leydig cells to drive steroid production. Giving both together reproduces the pituitary signal that is missing when the hypothalamic-pituitary axis is not working, or supplies a supraphysiological signal to recruit multiple follicles in assisted reproduction. The approved US indication is narrow: development of multiple follicles and pregnancy in ovulatory women as part of an assisted reproductive technology cycle. Older menotropins labeling also carried an indication, with concomitant human chorionic gonadotropin, for stimulating spermatogenesis in men with primary or secondary hypogonadotropic hypogonadism. In current practice, that male use is well documented in the literature even where it is not on the label of the marketed product. A systematic review and meta-analysis of 103 studies covering 5328 male patients with hypogonadotropic hypogonadism found human menopausal gonadotropin used in 40.8 percent of studies, and reported spermatogenesis in 86 percent of patients treated with human chorionic gonadotropin plus follicle-stimulating hormone against 40 percent with human chorionic gonadotropin alone (PMID: 38128110). A retrospective cohort of 122 Chinese men treated with combined human chorionic gonadotropin and human menopausal gonadotropin over 24 months reported spermatogenesis in 92.3 percent of men with partial disease and 74.7 percent of those with complete disease (PMID: 31464203). The safety profile is the reason this is a prescription drug. The label carries warnings for ovarian hyperstimulation syndrome, abnormal ovarian enlargement, pulmonary and vascular complications, ovarian torsion, multi-fetal gestation, congenital malformations, ectopic pregnancy, spontaneous abortion and ovarian neoplasms. In the registration trials the most common adverse reactions included abdominal pain in 6.7 percent, headache in 6.2 percent, ovarian hyperstimulation syndrome in 6.2 percent and injection site reactions in 3.9 percent (Menopur US prescribing information). For male athletes in tested sport, hMG is prohibited. The World Anti-Doping Agency prohibits chorionic gonadotrophin and luteinizing hormone and their releasing factors in male athletes under section S2 of the Prohibited List, and hMG contains luteinizing hormone activity. What is sold outside pharmacy channels as a research-use vial is not the approved product, has no verified potency in international units, and carries the contamination and mislabeling risks common to that market.", "lastReviewed": "2026-09-07T04:51:31.509Z", "url": "https://www.bodyhackguide.co/compound/hmg", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "reviewedBy": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" }, "mainContentOfPage": { "@type": "WebPageElement", "cssSelector": "main" }, "about": { "@type": "Drug", "name": "HMG (Human Menopausal Gonadotropin)", "alternateName": [ "Menotropins", "Human menopausal gonadotropin", "hMG", "Menotrophin", "Menopur", "Repronex", "Pergonal" ], "description": "HMG, or human menopausal gonadotropin, is not a synthetic research chemical. It is menotropins, an approved injectable fertility drug purified from the urine of postmenopausal women. It is a mixture rather than a single molecule: each vial of the currently marketed US product, Menopur, contains 75 international units of follicle-stimulating hormone activity and 75 international units of luteinizing hormone activity, and human chorionic gonadotropin from the urine source is detected in the product. The initial US approval for menotropins dates to 1975 (Menopur US prescribing information). The two hormones do different jobs. Follicle-stimulating hormone acts on granulosa cells in the ovary and on Sertoli cells in the testis to support gamete development. Luteinizing hormone acts on theca cells and, in men, on Leydig cells to drive steroid production. Giving both together reproduces the pituitary signal that is missing when the hypothalamic-pituitary axis is not working, or supplies a supraphysiological signal to recruit multiple follicles in assisted reproduction. The approved US indication is narrow: development of multiple follicles and pregnancy in ovulatory women as part of an assisted reproductive technology cycle. Older menotropins labeling also carried an indication, with concomitant human chorionic gonadotropin, for stimulating spermatogenesis in men with primary or secondary hypogonadotropic hypogonadism. In current practice, that male use is well documented in the literature even where it is not on the label of the marketed product. A systematic review and meta-analysis of 103 studies covering 5328 male patients with hypogonadotropic hypogonadism found human menopausal gonadotropin used in 40.8 percent of studies, and reported spermatogenesis in 86 percent of patients treated with human chorionic gonadotropin plus follicle-stimulating hormone against 40 percent with human chorionic gonadotropin alone (PMID: 38128110). A retrospective cohort of 122 Chinese men treated with combined human chorionic gonadotropin and human menopausal gonadotropin over 24 months reported spermatogenesis in 92.3 percent of men with partial disease and 74.7 percent of those with complete disease (PMID: 31464203). The safety profile is the reason this is a prescription drug. The label carries warnings for ovarian hyperstimulation syndrome, abnormal ovarian enlargement, pulmonary and vascular complications, ovarian torsion, multi-fetal gestation, congenital malformations, ectopic pregnancy, spontaneous abortion and ovarian neoplasms. In the registration trials the most common adverse reactions included abdominal pain in 6.7 percent, headache in 6.2 percent, ovarian hyperstimulation syndrome in 6.2 percent and injection site reactions in 3.9 percent (Menopur US prescribing information). For male athletes in tested sport, hMG is prohibited. The World Anti-Doping Agency prohibits chorionic gonadotrophin and luteinizing hormone and their releasing factors in male athletes under section S2 of the Prohibited List, and hMG contains luteinizing hormone activity. What is sold outside pharmacy channels as a research-use vial is not the approved product, has no verified potency in international units, and carries the contamination and mislabeling risks common to that market.", "activeIngredient": "HMG (Human Menopausal Gonadotropin)", "administrationRoute": "Subcutaneous injection, Intramuscular injection", "mechanismOfAction": "Menotropins supplies both gonadotropins at once. Follicle-stimulating hormone binds the FSH receptor, a G protein-coupled receptor on ovarian granulosa cells and testicular Sertoli cells, raising cyclic AMP and supporting follicular growth in women and spermatogenesis in men. Luteinizing hormone binds the LH/choriogonadotropin receptor on ovarian theca cells and testicular Leydig cells, driving androgen and progestogen synthesis; in men that is what raises intratesticular testosterone. Because the preparation is purified from urine, human chorionic gonadotropin is also detected in the product (Menopur US prescribing information). In men with hypogonadotropic hypogonadism, this receptor-level replacement is why human chorionic gonadotropin combined with an FSH source produces higher spermatogenesis rates than human chorionic gonadotropin alone (PMID: 38128110).", "dosageForm": "vial", "legalStatus": "Not approved for human use — research chemical", "warning": "For research purposes only. Not for human consumption." } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is HMG (Human Menopausal Gonadotropin) used for in research?", "acceptedAnswer": { "@type": "Answer", "text": "HMG, or human menopausal gonadotropin, is not a synthetic research chemical. It is menotropins, an approved injectable fertility drug purified from the urine of postmenopausal women. It is a mixture rather than a single molecule: each vial of the currently marketed US product, Menopur, contains 75 international units of follicle-stimulating hormone activity and 75 international units of luteinizing hormone activity, and human chorionic gonadotropin from the urine source is detected in the product. The initial US approval for menotropins dates to 1975 (Menopur US prescribing information). The two hormones do different jobs. Follicle-stimulating hormone acts on granulosa cells in the ovary and on Sertoli cells in the testis to support gamete development. Luteinizing hormone acts on theca cells and, in men, on Leydig cells to drive steroid production. Giving both together reproduces the pituitary signal that is missing when the hypothalamic-pituitary axis is not working, or supplies a supraphysiological signal to recruit multiple follicles in assisted reproduction. The approved US indication is narrow: development of multiple follicles and pregnancy in ovulatory women as part of an assisted reproductive technology cycle. Older menotropins labeling also carried an indication, with concomitant human chorionic gonadotropin, for stimulating spermatogenesis in men with primary or secondary hypogonadotropic hypogonadism. In current practice, that male use is well documented in the literature even where it is not on the label of the marketed product. A systematic review and meta-analysis of 103 studies covering 5328 male patients with hypogonadotropic hypogonadism found human menopausal gonadotropin used in 40.8 percent of studies, and reported spermatogenesis in 86 percent of patients treated with human chorionic gonadotropin plus follicle-stimulating hormone against 40 percent with human chorionic gonadotropin alone (PMID: 38128110). A retrospective cohort of 122 Chinese men treated with combined human chorionic gonadotropin and human menopausal gonadotropin over 24 months reported spermatogenesis in 92.3 percent of men with partial disease and 74.7 percent of those with complete disease (PMID: 31464203). The safety profile is the reason this is a prescription drug. The label carries warnings for ovarian hyperstimulation syndrome, abnormal ovarian enlargement, pulmonary and vascular complications, ovarian torsion, multi-fetal gestation, congenital malformations, ectopic pregnancy, spontaneous abortion and ovarian neoplasms. In the registration trials the most common adverse reactions included abdominal pain in 6.7 percent, headache in 6.2 percent, ovarian hyperstimulation syndrome in 6.2 percent and injection site reactions in 3.9 percent (Menopur US prescribing information). For male athletes in tested sport, hMG is prohibited. The World Anti-Doping Agency prohibits chorionic gonadotrophin and luteinizing hormone and their releasing factors in male athletes under section S2 of the Prohibited List, and hMG contains luteinizing hormone activity. What is sold outside pharmacy channels as a research-use vial is not the approved product, has no verified potency in international units, and carries the contamination and mislabeling risks common to that market." } }, { "@type": "Question", "name": "What forms does HMG (Human Menopausal Gonadotropin) come in?", "acceptedAnswer": { "@type": "Answer", "text": "HMG (Human Menopausal Gonadotropin) is available in vial form." } }, { "@type": "Question", "name": "How much does HMG (Human Menopausal Gonadotropin) cost?", "acceptedAnswer": { "@type": "Answer", "text": "Prices start at $54.99 across 1 verified vendor." } }, { "@type": "Question", "name": "How do I compare HMG (Human Menopausal Gonadotropin) vendors?", "acceptedAnswer": { "@type": "Answer", "text": "Compare prices, payment methods, shipping, and COA scores across 1 vendor." } } ] }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompound%2Fhmg) 100K+ researchers trust BodyHackGuide — Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 2. [Compounds](/compare) 3. HMG (Human Menopausal Gonadotropin) [Where to buy HMG (Human Menopausal Gonadotropin)](/buy/hmg) [HMG (Human Menopausal Gonadotropin) coupon codes](/coupons/hmg) [HMG (Human Menopausal Gonadotropin) protocol](/protocol/hmg) [Alternatives to HMG (Human Menopausal Gonadotropin)](/alternatives-to/hmg) [HMG (Human Menopausal Gonadotropin) side effects](/side-effects/hmg) 1. [Home](/) 3. [Compounds](/compare) 5. HMG (Human Menopausal Gonadotropin) # HMG (Human Menopausal Gonadotropin) Hormones & Endocrine (Non-GH) FDA Approved Download PDF Also known as: Menotropins, Human menopausal gonadotropin, hMG, Menotrophin, Menopur, Repronex, Pergonal HMG, or human menopausal gonadotropin, is not a synthetic research chemical. It is menotropins, an approved injectable fertility drug purified from the urine of postmenopausal women. Half-Life: Elimination half-life for follicle-stimulating hormone of 11 to 13 hours in the multiple-dose phase, similar for subcutaneous and intramuscular routes (Menopur US prescribing information) Route: Subcutaneous injection, Intramuscular injection Last reviewed: Sep 7, 2026 [ Hormones & Endocrine (Non-GH) Category ](/wiki#cat-hormones-&-endocrine-\(non-gh\)) FDA Approved Research Stage OverviewChemical InfoDosing & ProtocolsInteractionsResearchCompare Prices1 Related ## Overview ### Best Price Available ![Disguised Alpha logo](https://disguisedalpha.com/wp-content/themes/assets/logos/disguised-logo-2x.png) Disguised Alpha $54.99 1 vial (75 IU) · vial [Buy Now](https://disguisedalpha.com/product/hmg/?coupon=reddit) Compare 1 vendor ### At A Glance Mechanism Menotropins supplies both gonadotropins at once. Follicle-stimulating hormone binds the FSH receptor, a G protein-coupled receptor on ovarian granulosa cells and testicular Sertoli cells, raising cyclic AMP and supporting follicular growth in women and spermatogenesis in men. Lut… Half-Life Elimination half-life for follicle-stimulating hormone of 11 to 13 hours in the multiple-dose phase, similar for subcutaneous and intramuscular routes (Menopur US prescribing information) Routes Subcutaneous injection Intramuscular injection Potential Benefits Testicular growth in almost all patients, spermatogenesis in approximately 80 percent and pregnancy rates in the range of 50 percent with combined human chorionic gonadotropin and FSH therapy in men with hypogonadotropic hypogonadism (PMID: 32445446) Spermatogenesis in 86 percent of men with hypogonadotropic hypogonadism treated with human chorionic gonadotropin plus an FSH source, against 40 percent with human chorionic gonadotropin alone, in a meta-analysis of 103 studies and 5328 patients (PMID: 38128110) Spermatogenesis in 92.3 percent of men with partial and 74.7 percent with complete congenital hypogonadotropic hypogonadism after combined human chorionic gonadotropin and human menopausal gonadotropin treatment in a 122-patient cohort (PMID: 31464203) Increased testicular volume, penile size and testosterone in over 98 percent of analyses of gonadotropin therapy for pubertal induction in males (PMID: 38128110) ### Overview HMG, or human menopausal gonadotropin, is not a synthetic research chemical. It is menotropins, an approved injectable fertility drug purified from the urine of postmenopausal women. It is a mixture rather than a single molecule: each vial of the currently marketed US product, Menopur, contains 75 international units of follicle-stimulating hormone activity and 75 international units of luteinizing hormone activity, and human chorionic gonadotropin from the urine source is detected in the product. The initial US approval for menotropins dates to 1975 (Menopur US prescribing information). The two hormones do different jobs. Follicle-stimulating hormone acts on granulosa cells in the ovary and on Sertoli cells in the testis to support gamete development. Luteinizing hormone acts on theca cells and, in men, on Leydig cells to drive steroid production. Giving both together reproduces the pituitary signal that is missing when the hypothalamic-pituitary axis is not working, or supplies a supraphysiological signal to recruit multiple follicles in assisted reproduction. The approved US indication is narrow: development of multiple follicles and pregnancy in ovulatory women as part of an assisted reproductive technology cycle. Older menotropins labeling also carried an indication, with concomitant human chorionic gonadotropin, for stimulating spermatogenesis in men with primary or secondary hypogonadotropic hypogonadism. In current practice, that male use is well documented in the literature even where it is not on the label of the marketed product. A systematic review and meta-analysis of 103 studies covering 5328 male patients with hypogonadotropic hypogonadism found human menopausal gonadotropin used in 40.8 percent of studies, and reported spermatogenesis in 86 percent of patients treated with human chorionic gonadotropin plus follicle-stimulating hormone against 40 percent with human chorionic gonadotropin alone (PMID: 38128110). A retrospective cohort of 122 Chinese men treated with combined human chorionic gonadotropin and human menopausal gonadotropin over 24 months reported spermatogenesis in 92.3 percent of men with partial disease and 74.7 percent of those with complete disease (PMID: 31464203). The safety profile is the reason this is a prescription drug. The label carries warnings for ovarian hyperstimulation syndrome, abnormal ovarian enlargement, pulmonary and vascular complications, ovarian torsion, multi-fetal gestation, congenital malformations, ectopic pregnancy, spontaneous abortion and ovarian neoplasms. In the registration trials the most common adverse reactions included abdominal pain in 6.7 percent, headache in 6.2 percent, ovarian hyperstimulation syndrome in 6.2 percent and injection site reactions in 3.9 percent (Menopur US prescribing information). For male athletes in tested sport, hMG is prohibited. The World Anti-Doping Agency prohibits chorionic gonadotrophin and luteinizing hormone and their releasing factors in male athletes under section S2 of the Prohibited List, and hMG contains luteinizing hormone activity. What is sold outside pharmacy channels as a research-use vial is not the approved product, has no verified potency in international units, and carries the contamination and mislabeling risks common to that market. ### Potential Research Fields Assisted reproduction Male hypogonadotropic hypogonadism Reproductive endocrinology ## Chemical Information IUPAC Name Not yet available CAS Number Not yet available Molecular Formula Not yet available Molecular Mass Not yet available Chemical data is being compiled for this compound. ## Dosing & Protocols ### Unlock Dosing Protocols Free account gets you: - View beginner, intermediate & advanced protocols - See weight-based dosing calculations - Access cycle length & frequency data [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Research ### Unlock Research Data Free account gets you: - Browse PubMed study summaries - See clinical trial phases & results - Access mechanism of action details [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Interactions ### Contraindications Labeled contraindications: prior hypersensitivity to menotropins products, high follicle-stimulating hormone levels indicating primary ovarian failure, pregnancy, uncontrolled non-gonadal endocrinopathies, sex hormone dependent tumors of the reproductive tract, pituitary or hypothalamic tumors, abnormal uterine bleeding of undetermined origin, and ovarian cysts or enlargement not due to polycystic ovary syndrome (Menopur US prescribing information). In men, older menotropins labeling listed normal gonadotropin levels, raised gonadotropin levels indicating primary testicular failure, and infertility from causes other than hypogonadotropic hypogonadism as contraindications. Research Disclaimer This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds. Best Price $54.99 Best $/mg — Vendors 1 Listings 1 vial [Sign in for alerts ](/auth) Form Allvial Sort Price $/mg Vendor Vendor Product Form Qty Price $/mg Coupon ![Disguised Alpha logo](https://disguisedalpha.com/wp-content/themes/assets/logos/disguised-logo-2x.png) [Disguised Alpha](/vendor/disguised-alpha) [50 ](/vendor-trust-scorecard) 🇺🇸 US 🇪🇺 EU 🇬🇧 UK HMG 75 IU vial 1 vial (75 IU) ● In Stock $54.99 BEST — — [Buy](https://disguisedalpha.com/product/hmg/?coupon=reddit) Get HMG (Human Menopausal Gonadotropin) Price Drop Alerts Set a target price and we'll notify you when any vendor drops below it. Current lowest: $54.99 [Sign in to set alerts](/auth) ### Sign in to leave a review Reviews on BodyHackGuide are tied to verified user accounts and moderated before publishing. Sign in (free, no spam) to share your experience with HMG (Human Menopausal Gonadotropin). [Sign in](/auth) Current low $54.99 as of Sep 7, 2026 7-day low $54.99 30-day low $54.99 30-day change — baseline building Tracking since Sep 7, 2026 · 1 data point ### Vendors Selling HMG (Human Menopausal Gonadotropin) [ ![Disguised Alpha logo](https://disguisedalpha.com/wp-content/themes/assets/logos/disguised-logo-2x.png) #### Disguised Alpha 1 listing · from $54.99 ](/vendor/disguised-alpha) How we score these vendors Every supplier above is graded 0–100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank. [View Scorecard](/vendors/scorecard) ### Related Compounds [View All](/wiki) [ ### Gonadorelin Hormones & Endocrine (Non-GH) FDA Approved Gonadorelin is the synthetic, pharmaceutically manufactured version of endogenous gonadotropin-releasing hormone (GnRH) — a ten-amino-acid decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) first isolated, sequenced, and synthesized by Andrew V. t½ ~2-10 minutes (plasma; rapid enzymatic degradation by peptidases) 100-300 473 studies View Profile ](/compound/gonadorelin)[ ### Kisspeptin-10 Hormones & Endocrine (Non-GH) Phase 2 Kisspeptin-10 (KP-10, metastin 45-54) is the C-terminal decapeptide fragment of kisspeptin, a neuropeptide product of the KISS1 gene that has emerged over the past two decades as the master regulator of reproductive endocrinology in humans and all other vertebrates studied to date. t½ ~4 minutes (KP-10, plasma) - reflecting rapid peptidase degradation. The downstream LH/FSH response nonetheless persists ~1-2 hours after a dose. For comparison, kisspeptin-54 has a measured plasma half-life of ~27 minutes. 597 studies View Profile ](/compound/kisspeptin-10)[ ### Oxytocin Hormones & Endocrine (Non-GH) FDA Approved Oxytocin is a nine-amino-acid cyclic peptide hormone (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2) synthesized in magnocellular neurons of the hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), then transported along axons to the posterior pituitary for release into systemic circulation. t½ ~1-6 minutes (plasma); central/behavioral effects outlast plasma clearance, typically ~30-120 minutes after intranasal dosing 602 studies View Profile ](/compound/oxytocin) [ View Full Dosage Guide → Protocols, calculator & safety for HMG (Human Menopausal Gonadotropin) ](/guides/dosage/hmg) ### Best Price ![Disguised Alpha logo](https://disguisedalpha.com/wp-content/themes/assets/logos/disguised-logo-2x.png) Disguised Alpha $54.99 [Buy Now](https://disguisedalpha.com/product/hmg/?coupon=reddit) 1 vendors · 1 listings ### Research Score 15 0 PubMed studies ### Quality Indicators Data Completeness 50% Description Mechanism of Action Chemical Data Dosing Protocols Safety Profile PubMed Studies Interactions Vendor Listings ### Quick Facts Half-Life Elimination half-life for follicle-stimulating hormone of 11 to 13 hours in the multiple-dose phase, similar for subcutaneous and intramuscular routes (Menopur US prescribing information) Administration Subcutaneous injection, Intramuscular injection Trial Phase FDA Approved 0 [Full Dosage Guide](/guides/dosage/hmg)[Calculate Your Dose](/tools/reconstitution) Research Disclaimer This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use. ## Frequently Asked Questions What is HMG (Human Menopausal Gonadotropin) used for in research? HMG, or human menopausal gonadotropin, is not a synthetic research chemical. It is menotropins, an approved injectable fertility drug purified from the urine of postmenopausal women. It is a mixture rather than a single molecule: each vial of the currently marketed US product, Menopur, contains 75 international units of follicle-stimulating hormone activity and 75 international units of luteinizing hormone activity, and human chorionic gonadotropin from the urine source is detected in the product. The initial US approval for menotropins dates to 1975 (Menopur US prescribing information). The two hormones do different jobs. Follicle-stimulating hormone acts on granulosa cells in the ovary and on Sertoli cells in the testis to support gamete development. Luteinizing hormone acts on theca cells and, in men, on Leydig cells to drive steroid production. Giving both together reproduces the pituitary signal that is missing when the hypothalamic-pituitary axis is not working, or supplies a supraphysiological signal to recruit multiple follicles in assisted reproduction. The approved US indication is narrow: development of multiple follicles and pregnancy in ovulatory women as part of an assisted reproductive technology cycle. Older menotropins labeling also carried an indication, with concomitant human chorionic gonadotropin, for stimulating spermatogenesis in men with primary or secondary hypogonadotropic hypogonadism. In current practice, that male use is well documented in the literature even where it is not on the label of the marketed product. A systematic review and meta-analysis of 103 studies covering 5328 male patients with hypogonadotropic hypogonadism found human menopausal gonadotropin used in 40.8 percent of studies, and reported spermatogenesis in 86 percent of patients treated with human chorionic gonadotropin plus follicle-stimulating hormone against 40 percent with human chorionic gonadotropin alone (PMID: 38128110). A retrospective cohort of 122 Chinese men treated with combined human chorionic gonadotropin and human menopausal gonadotropin over 24 months reported spermatogenesis in 92.3 percent of men with partial disease and 74.7 percent of those with complete disease (PMID: 31464203). The safety profile is the reason this is a prescription drug. The label carries warnings for ovarian hyperstimulation syndrome, abnormal ovarian enlargement, pulmonary and vascular complications, ovarian torsion, multi-fetal gestation, congenital malformations, ectopic pregnancy, spontaneous abortion and ovarian neoplasms. In the registration trials the most common adverse reactions included abdominal pain in 6.7 percent, headache in 6.2 percent, ovarian hyperstimulation syndrome in 6.2 percent and injection site reactions in 3.9 percent (Menopur US prescribing information). For male athletes in tested sport, hMG is prohibited. The World Anti-Doping Agency prohibits chorionic gonadotrophin and luteinizing hormone and their releasing factors in male athletes under section S2 of the Prohibited List, and hMG contains luteinizing hormone activity. What is sold outside pharmacy channels as a research-use vial is not the approved product, has no verified potency in international units, and carries the contamination and mislabeling risks common to that market. What forms does HMG (Human Menopausal Gonadotropin) come in? HMG (Human Menopausal Gonadotropin) is available in vial form. How much does HMG (Human Menopausal Gonadotropin) cost? Prices start at $54.99 across 1 verified vendor. How do I compare HMG (Human Menopausal Gonadotropin) vendors? Compare prices, payment methods, shipping, and COA scores across 1 vendor. ## Research Tools [ ### Peptide Calculator Reconstitution & syringe units ](/tools/reconstitution)[ ### Reconstitution Guide How to mix, step by step ](/guides/how-to-reconstitute-peptides)[ ### Nasal Spray Calc mL per actuation ](/tools/intranasal)[ ### Half-Life Visualizer Decay curves ](/tools/halflife) ## Related Compounds [View All](/wiki) [ ### Gonadorelin Hormones & Endocrine (Non-GH) FDA Approved Gonadorelin is the synthetic, pharmaceutically manufactured version of endogenous gonadotropin-releasing hormone (GnRH) — a ten-amino-acid decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) first isolated, sequenced, and synthesized by Andrew V. t½ ~2-10 minutes (plasma; rapid enzymatic degradation by peptidases) 100-300 473 studies View Profile ](/compound/gonadorelin)[ ### Kisspeptin-10 Hormones & Endocrine (Non-GH) Phase 2 Kisspeptin-10 (KP-10, metastin 45-54) is the C-terminal decapeptide fragment of kisspeptin, a neuropeptide product of the KISS1 gene that has emerged over the past two decades as the master regulator of reproductive endocrinology in humans and all other vertebrates studied to date. t½ ~4 minutes (KP-10, plasma) - reflecting rapid peptidase degradation. The downstream LH/FSH response nonetheless persists ~1-2 hours after a dose. For comparison, kisspeptin-54 has a measured plasma half-life of ~27 minutes. 597 studies View Profile ](/compound/kisspeptin-10)[ ### Oxytocin Hormones & Endocrine (Non-GH) FDA Approved Oxytocin is a nine-amino-acid cyclic peptide hormone (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2) synthesized in magnocellular neurons of the hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), then transported along axons to the posterior pituitary for release into systemic circulation. t½ ~1-6 minutes (plasma); central/behavioral effects outlast plasma clearance, typically ~30-120 minutes after intranasal dosing 602 studies View Profile ](/compound/oxytocin) Free 2026 Peptide Cheat Sheet — 50 pages, PDF Reconstitution math, concentration charts, half-lives, and vendor trust tiers. The reference we wish we had on day one. [Download Free](/guides/peptide-cheat-sheet-download?utm_source=compound-hmg) ### Need bloodwork before starting? Full hormone + metabolic panels from Anabolic Insights. Code CHONCH for first-order discount. [Order Bloodwork](https://anabolicinsights.ai/?ref=nwm2zjb) ![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub — compound pricing, brain health protocols, dosing tools, and vendor reviews. 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