--- title: "Adamax: Dosing & Vendor Prices | BodyHackGuide" description: "Adamax: dosing protocols, mechanism & side effects. Compare 1 current vendor prices." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compounds", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "Adamax" } ] }, { "@context": "https://schema.org", "@type": "Product", "name": "Adamax", "description": "Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. It modifies the parent Semax sequence (Met-Glu-His-Phe-Pro-Gly-Pro) with the N-terminal acetyl and C-terminal amide groups characteristic of the cognitive enhancer P-21, plus an adamantane-derived structural modification that improves blood-brain-barrier (BBB) penetration and metabolic stability versus standard Semax. As of 2026, Adamax has very limited peer-reviewed primary literature - most of the publicly available information comes from synthetic peptide chemistry catalogs, vendor monographs, and community-aggregated dosing protocols rather than published clinical trials. It is not approved by the United States Food and Drug Administration (FDA) for any indication and falls into the research peptide category in the same regulatory tier as Semax, Selank, and P-21. Reported nonclinical observations describe Adamax as upregulating brain-derived neurotrophic factor (BDNF) expression and modulating dopamine D2 receptor sensitivity in mesolimbic motivation circuits (ventral tegmental area, nucleus accumbens). The adamantane modification is hypothesized to extend the peptide's receptor binding window beyond the typical Semax half-life - community-reported protocols cite once-daily or every-other-day dosing maintaining receptor-level effects across a 72-hour window. Researchers exploring Adamax should be aware of the limited public safety data, the absence of completed clinical trials, and the structural similarity to Semax - meaning much of what is known about Semax's pharmacology (anxiolytic, neurotrophic, BDNF-modulating effects) is reasonably extrapolated to Adamax, but Adamax's specific receptor-level kinetics, long-term safety, and dose-response curves remain under-characterized.", "url": "https://www.bodyhackguide.co/compound/adamax", "image": "https://www.bodyhackguide.co/og-image.png", "brand": { "@type": "Brand", "name": "Research Compound" }, "offers": { "@type": "AggregateOffer", "lowPrice": "69.99", "highPrice": "69.99", "priceCurrency": "USD", "offerCount": "1", "availability": "https://schema.org/InStock", "offers": [ { "@type": "Offer", "price": "69.99", "priceCurrency": "USD", "availability": "https://schema.org/InStock", "itemCondition": "https://schema.org/NewCondition", "url": "https://bhglabs.co/product/adamax-10mg-atomized-solution/?ref=zmgqyxku", "seller": { "@type": "Organization", "name": "BHG Labs", "url": "https://bhglabs.co/?ref=zmgqyxku" }, "name": "Adamax 10mg nasal" } ] } }, { "@context": "https://schema.org", "@type": "MedicalWebPage", "name": "Adamax", "description": "Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. It modifies the parent Semax sequence (Met-Glu-His-Phe-Pro-Gly-Pro) with the N-terminal acetyl and C-terminal amide groups characteristic of the cognitive enhancer P-21, plus an adamantane-derived structural modification that improves blood-brain-barrier (BBB) penetration and metabolic stability versus standard Semax. As of 2026, Adamax has very limited peer-reviewed primary literature - most of the publicly available information comes from synthetic peptide chemistry catalogs, vendor monographs, and community-aggregated dosing protocols rather than published clinical trials. It is not approved by the United States Food and Drug Administration (FDA) for any indication and falls into the research peptide category in the same regulatory tier as Semax, Selank, and P-21. Reported nonclinical observations describe Adamax as upregulating brain-derived neurotrophic factor (BDNF) expression and modulating dopamine D2 receptor sensitivity in mesolimbic motivation circuits (ventral tegmental area, nucleus accumbens). The adamantane modification is hypothesized to extend the peptide's receptor binding window beyond the typical Semax half-life - community-reported protocols cite once-daily or every-other-day dosing maintaining receptor-level effects across a 72-hour window. Researchers exploring Adamax should be aware of the limited public safety data, the absence of completed clinical trials, and the structural similarity to Semax - meaning much of what is known about Semax's pharmacology (anxiolytic, neurotrophic, BDNF-modulating effects) is reasonably extrapolated to Adamax, but Adamax's specific receptor-level kinetics, long-term safety, and dose-response curves remain under-characterized.", "lastReviewed": "2026-05-04T11:34:50.333+00:00", "url": "https://www.bodyhackguide.co/compound/adamax", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "reviewedBy": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" }, "mainContentOfPage": { "@type": "WebPageElement", "cssSelector": "main" }, "about": { "@type": "Drug", "name": "Adamax", "alternateName": [ "ADAMAX", "Ac-MEHFPGPAG-NH2", "Adamantane Semax", "Adamax Peptide" ], "description": "Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. It modifies the parent Semax sequence (Met-Glu-His-Phe-Pro-Gly-Pro) with the N-terminal acetyl and C-terminal amide groups characteristic of the cognitive enhancer P-21, plus an adamantane-derived structural modification that improves blood-brain-barrier (BBB) penetration and metabolic stability versus standard Semax. As of 2026, Adamax has very limited peer-reviewed primary literature - most of the publicly available information comes from synthetic peptide chemistry catalogs, vendor monographs, and community-aggregated dosing protocols rather than published clinical trials. It is not approved by the United States Food and Drug Administration (FDA) for any indication and falls into the research peptide category in the same regulatory tier as Semax, Selank, and P-21. Reported nonclinical observations describe Adamax as upregulating brain-derived neurotrophic factor (BDNF) expression and modulating dopamine D2 receptor sensitivity in mesolimbic motivation circuits (ventral tegmental area, nucleus accumbens). The adamantane modification is hypothesized to extend the peptide's receptor binding window beyond the typical Semax half-life - community-reported protocols cite once-daily or every-other-day dosing maintaining receptor-level effects across a 72-hour window. Researchers exploring Adamax should be aware of the limited public safety data, the absence of completed clinical trials, and the structural similarity to Semax - meaning much of what is known about Semax's pharmacology (anxiolytic, neurotrophic, BDNF-modulating effects) is reasonably extrapolated to Adamax, but Adamax's specific receptor-level kinetics, long-term safety, and dose-response curves remain under-characterized.", "activeIngredient": "Adamax", "administrationRoute": "Subcutaneous, Intranasal", "mechanismOfAction": "BDNF and TrkB Receptor Pathway Adamax is reported to upregulate brain-derived neurotrophic factor (BDNF) expression in the hippocampus and modulate the sensitivity of TrkB receptors (the primary BDNF receptor). BDNF is a master regulator of neuronal plasticity, dendritic spine formation, and long-term potentiation - the molecular substrate of memory formation. The TrkB sensitivity boost is the proposed mechanism for the cognitive and mood-stabilizing effects observed at research doses. Dopamine D2 Receptor Modulation Adamax is reported to modulate D2 receptor sensitivity in the ventral tegmental area and nucleus accumbens - the central motivation and reward circuits. This dopaminergic modulation overlaps with Semax's reported effects on the same system but is described as more sustained, hypothesized to result from the adamantane modification. Blood-Brain Barrier Penetration The adamantane structural element is shared with several CNS-acting drugs (e.g., amantadine, memantine) where it confers improved BBB permeability versus parent compounds. In Adamax, this modification is hypothesized to increase the fraction of peripherally administered peptide reaching central targets - meaning lower nasal or subcutaneous doses can produce comparable central effects to higher doses of unmodified Semax. Duration of Effect (Community-Reported) Community reports describe a subjectively long duration of effect (anecdotally ~2-3 days), supporting once-daily or every-other-day dosing; no receptor-occupancy or pharmacokinetic data exist. This subjective duration is described as considerably longer than the ~30-60 minute serum half-life of intranasal Semax and is one of the primary differentiators in the community comparison to Semax and Selank.", "dosageForm": "nasal", "legalStatus": "Not approved for human use — research chemical", "warning": "For research purposes only. Not for human consumption." } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Is Adamax just Semax with a chemistry tweak, or is it actually different?", "acceptedAnswer": { "@type": "Answer", "text": "It's a structural derivative - Semax's Ac-MEHFPGP core plus an Ala-Gly tail capped with an adamantyl group borrowed from P-21. Same primary mechanism (BDNF / TrkB / D2 modulation), but the adamantane modification is hypothesized to improve blood-brain-barrier penetration and extend the subjective duration of effect to roughly 2-3 days vs Semax's ~30-60 minute serum half-life. No pharmacokinetic data exist for Adamax, so this is a community-reported difference in duration, not a measured one. The pharmacology is similar in kind, different in duration." } }, { "@type": "Question", "name": "Why are there no PubMed studies for Adamax?", "acceptedAnswer": { "@type": "Answer", "text": "Adamax was first synthesized by Ceretropic (a research-peptide vendor) circa 2016, not a Russian academic institute, so it never entered the formal Semax / Selank publication pipeline. The Russian Institute of Molecular Genetics RAS is responsible for Semax and Selank - but they did not develop Adamax. Effects are extrapolated from Semax data and community reports; primary literature under the 'Adamax' name does not exist as of 2026." } }, { "@type": "Question", "name": "Intranasal or subcutaneous - which route do most researchers use?", "acceptedAnswer": { "@type": "Answer", "text": "Both are documented. Subcutaneous is more common in current research protocols because the adamantyl tail makes the molecule larger and more lipophilic than parent Semax, which slows nasal absorption. Intranasal protocols exist but require higher doses to achieve comparable central effects. Subcutaneous at 500-1500 mcg every other day is the dominant community pattern." } }, { "@type": "Question", "name": "How does dosing schedule differ from Semax?", "acceptedAnswer": { "@type": "Answer", "text": "Semax is typically dosed daily (often multiple times per day) because of its short serum half-life. Adamax community protocols describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; note there are no pharmacokinetic or receptor-occupancy data behind this. Daily dosing is not necessary and may increase the risk of D2 receptor desensitization without proportionate benefit." } }, { "@type": "Question", "name": "Can Adamax be stacked with Semax or P-21?", "acceptedAnswer": { "@type": "Answer", "text": "Caution. All three modulate overlapping receptor systems (BDNF / TrkB / D2). Simultaneous full-dose stacking has not been characterized in any controlled setting and risks additive receptor desensitization. If combining, conservative low-dose protocols and longer washout windows between cycles are sensible. Adamax + Selank is a more common pairing because the mechanisms (BDNF / D2 vs GABAergic / serotonergic anxiolysis) are complementary rather than overlapping." } }, { "@type": "Question", "name": "What does an Adamax cycle look like end-to-end?", "acceptedAnswer": { "@type": "Answer", "text": "A typical research cycle is 4-8 weeks with at least a 2-week washout. Beginners start at 500 mcg subcutaneous every other day to assess tolerance. Intermediate users move to 750-1000 mcg three times per week. Advanced protocols cap around 1500-2000 mcg every other day. Effects build over the first 1-2 weeks; subjective plateau is typically reported at weeks 3-4." } }, { "@type": "Question", "name": "Are there any known safety red flags?", "acceptedAnswer": { "@type": "Answer", "text": "There are no formal toxicology studies. Anecdotal reports cite mild side effects similar to Semax: headache (often dose-related), transient insomnia if dosed in the evening, occasional irritability or mild mood elevation. No reports of serious adverse events in the public community datasets - but this reflects underreporting in unregulated use, not formal safety clearance. Avoid in pregnancy, lactation, active psychiatric instability, and uncontrolled hypertension." } } ] }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompound%2Fadamax) 100K+ researchers trust BodyHackGuide. Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 3. [Compounds](/compare) 5. Adamax ![BHG Labs logo](https://bhglabs.co/store/wp-content/uploads/2026/06/logo-full.png) Lowest price per mg $7.00/mg · $69.99 for 10mg at BHG Labs BHG20[Buy at BHG Labs](https://www.bodyhackguide.co/go/bhg-labs?utm_source=compound-sticky-bar&utm_campaign=c257ff60-0745-41c8-a6e0-154da5df701f&utm_medium=best-price-cta) BHG Labs shares common ownership with BodyHackGuide, and we earn a commission on purchases through our links. [🛒 Where to buy Adamax](/buy/adamax)[🏷️ Adamax coupon codes](/coupons/adamax)[📋 Adamax protocol](/protocol/adamax)[🔄 Alternatives to Adamax](/alternatives-to/adamax)[⚠️ Adamax side effects](/side-effects/adamax) 1. [Home](/) 3. [Compounds](/compare) 5. Adamax # Adamax Nootropic Peptide Preclinical / Research compound Download PDF Also known as: ADAMAX, Ac-MEHFPGPAG-NH2, Adamantane Semax, Adamax Peptide Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. It modifies the parent Semax sequence (Met-Glu-His-Phe-Pro-Gly-Pro) with the N-terminal acetyl and C-terminal amide groups characteristic of the cognitive enhancer P-21, plus an adamantane-derived structural modification that improves blood-brain-barrier (BBB) penetration and metabolic stability versus standard Semax. As of 2026, Adamax has very limited peer-reviewed primary literature - most of the publicly available information comes from synthetic peptide chemistry catalogs, vendor monographs, and community-aggregated dosing protocols rather than published clinical trials. Half-Life: No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. Route: Subcutaneous, Intranasal MW: ~983 Da (peptide backbone Ac-MEHFPGP-AG-NH2, calculated average mass); intact adamantane-conjugated molecule not formally characterized (vendor estimate ~1098 g/mol, unconfirmed by mass spectrometry) CAS: Not assigned (research compound, no CAS registry entry as of 2026) Last reviewed: May 4, 2026 [ Nootropic Peptide Category ](/wiki#cat-nootropic-peptide) Preclinical / Research compound Research Stage OverviewChemical InfoDosing & ProtocolsInteractionsResearchCompare Prices1 Related ## Overview ### Lowest Price per mg ![BHG Labs logo](https://bhglabs.co/store/wp-content/uploads/2026/06/logo-full.png) BHG Labs $69.99($7.00/mg) 1 bottle · nasal [Buy Now](https://bhglabs.co/product/adamax-10mg-atomized-solution/?ref=zmgqyxku&coupon=BHG20) Coupon: `BHG20`Copy BHG Labs shares common ownership with BodyHackGuide, and we earn a commission on purchases through our links. Compare 1 vendor ### At A Glance Mechanism BDNF and TrkB Receptor Pathway… Half-Life No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. Dosing Once daily or every-other-day (3x/week typical) Dose Range 500-2000 mcg subcutaneous (community research dosing)mcg Routes Subcutaneous Intranasal Common Vials 2mgmg 5mgmg 10mgmg Potential Benefits BDNF and TrkB receptor sensitivity upregulation in hippocampal models Dopaminergic D2 receptor modulation in motivation circuits (VTA / nucleus accumbens) Improved blood-brain-barrier penetration vs. standard Semax (adamantane modification) Subjectively long duration of effect (anecdotally ~2-3 days) supporting every-other-day dosing (no pharmacokinetic data) Cognitive enhancement reported in community protocols (focus, memory consolidation) Mood stabilization and motivation effects (anecdotal) No reported tolerance buildup at standard 4-8 week cycles Safety Notes Common Mild headache during first 1-2 days of dosing (typically self-resolving) Transient irritability at doses above 1 mg Sleep onset delay if dosed in the evening Subcutaneous injection-site irritation Serious No serious adverse events published in peer-reviewed literature Long-term human safety data does not exist Caution in individuals with bipolar disorder or psychosis history (dopaminergic modulation) ### Overview Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. It modifies the parent Semax sequence (Met-Glu-His-Phe-Pro-Gly-Pro) with the N-terminal acetyl and C-terminal amide groups characteristic of the cognitive enhancer P-21, plus an adamantane-derived structural modification that improves blood-brain-barrier (BBB) penetration and metabolic stability versus standard Semax. As of 2026, Adamax has very limited peer-reviewed primary literature - most of the publicly available information comes from synthetic peptide chemistry catalogs, vendor monographs, and community-aggregated dosing protocols rather than published clinical trials. It is not approved by the United States Food and Drug Administration (FDA) for any indication and falls into the research peptide category in the same regulatory tier as Semax, Selank, and P-21. Reported nonclinical observations describe Adamax as upregulating brain-derived neurotrophic factor (BDNF) expression and modulating dopamine D2 receptor sensitivity in mesolimbic motivation circuits (ventral tegmental area, nucleus accumbens). The adamantane modification is hypothesized to extend the peptide's receptor binding window beyond the typical Semax half-life - community-reported protocols cite once-daily or every-other-day dosing maintaining receptor-level effects across a 72-hour window. Researchers exploring Adamax should be aware of the limited public safety data, the absence of completed clinical trials, and the structural similarity to Semax - meaning much of what is known about Semax's pharmacology (anxiolytic, neurotrophic, BDNF-modulating effects) is reasonably extrapolated to Adamax, but Adamax's specific receptor-level kinetics, long-term safety, and dose-response curves remain under-characterized. ### Potential Research Fields Cognitive enhancement BDNF research Dopaminergic modulation Nootropic peptides Blood-brain barrier ## Chemical Information IUPAC Name N-acetyl-L-methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-prolyl-glycyl-L-prolyl-L-alanyl-glycinamide CAS Number Not assigned (research compound, no CAS registry entry as of 2026) Molecular Formula C49H67N13O14S Molecular Mass 1098.20 g/mol (calculated; awaiting MS confirmation) Amino Acid Sequence Ac-Met-Glu-His-Phe-Pro-Gly-Pro-Ala-Gly-NH2 with C-terminal adamantyl modification (acetylated N-terminus, amidated C-terminus) ## Dosing & Protocols ### Dosing Summary Dose 500-2000 mcg Route Subcutaneous (most common) or intranasal Frequency Once daily, EOD, or 3x per week Duration 4-8 weeks per cycle ### Titration Schedule Step Weeks Dose Purpose Week 1 — 500 mcg EOD Assess tolerance Weeks 2-4 — 750-1000 mcg Therapeutic dosing Weeks 5-8 (advanced) — 1000-1500 mcg Optimization ### Beginner Protocol ### Intermediate Protocol ### Advanced Protocol ### Reconstitution Guide Solvent bacteriostatic water Volume 2 mL Storage Refrigerate (2-8°C) Stability Up to 30 days refrigerated Common Vial Sizes 2mg 5mg 10mg Instructions 1 Clean the vial stopper with an alcohol swab 2 Draw 2 mL bacteriostatic water into a syringe 3 Insert needle into vial and slowly inject solvent down the side wall 4 Gently swirl (never shake) until fully dissolved 5 Store refrigerate (2-8°c) after reconstitution Important - • Never shake — gently swirl to preserve peptide bonds - • Use bacteriostatic water for multi-dose vials - • Discard if solution appears cloudy or discolored [Open Reconstitution Calculator](/tools/reconstitution) ### Detailed Reconstitution Instructions ### Stacking Notes ### Additional Dosage Notes [Full Adamax Dosing Guide](/guides/dosage/adamax) ### Unlock Dosing Protocols Free account gets you: - View beginner, intermediate & advanced protocols - See weight-based dosing calculations - Access cycle length & frequency data [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Research [PubMed Results](https://pubmed.ncbi.nlm.nih.gov/?term=Adamax%20peptide%20nootropic)Last updated: May 4, 2026 ### Key Research Findings No completed Phase I, II, or III clinical trials in humans. All available data comes from synthesis chemistry, in vitro receptor binding studies, and aggregated community-reported research protocols. Comparisons to Semax (which has limited Russian clinical data) are commonly cited but not directly transferable. ### Safety & Side Effects Limited safety data due to absence of formal clinical trials. Anecdotal reports from community use describe: - Mild headache during the first 1-2 days of dosing (resolves with continued use or dose reduction) - Transient irritability or restlessness at higher doses (>1 mg) - Mild sleep onset delay if dosed late in the day - Injection-site irritation with subcutaneous administration No serious adverse events have been published in peer-reviewed literature. Long-term safety data does not exist. As with all research peptides, individual response variability is high. [Browse Studies on PubMed](https://pubmed.ncbi.nlm.nih.gov/?term=Adamax%20peptide%20nootropic) ### Unlock Research Data Free account gets you: - Browse PubMed study summaries - See clinical trial phases & results - Access mechanism of action details [Create free account](/auth)[Sign in](/auth) 2,800+ researchers already in ## Interactions ### Interaction Matrix All(6) Compatible(2) Caution(4) Avoid Semax Caution Selank Synergistic Dihexa Compatible P-21 Caution Wellbutrin Caution MAOIs Caution ### Contraindications Not approved for human use. Caution in individuals with bipolar disorder, psychosis history, or active dopaminergic medication therapy. Not for use during pregnancy or breastfeeding. No safety data exists for users with active malignancy, autoimmune disease, or seizure disorders. Research Disclaimer This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds. Best Price $69.99 Best $/mg $6.9990 Vendors 1 Listings 1 nasal [Sign in for alerts ](/auth) Form Allnasal Sort Price $/mg Vendor BHG Labs shares common ownership with BodyHackGuide, and we earn a commission on purchases through our links. Vendor Product Form Qty Price $/mg Coupon ![BHG Labs logo](https://bhglabs.co/store/wp-content/uploads/2026/06/logo-full.png) [BHG Labs](/vendor/bhg-labs) [70 ](/vendor-trust-scorecard) 🇺🇸 US Adamax 10mg Atomized Solution nasal 1 bottle ● In Stock $69.99 BEST $6.999 BHG20 [Buy](https://bhglabs.co/product/adamax-10mg-atomized-solution/?ref=zmgqyxku&coupon=BHG20) Get Adamax Price Drop Alerts Set a target price and we'll notify you when any vendor drops below it. Current lowest: $69.99 [Sign in to set alerts](/auth) ### Sign in to leave a review Reviews on BodyHackGuide are tied to verified user accounts and moderated before publishing. Sign in (free, no spam) to share your experience with Adamax. [Sign in](/auth) Current low $74.99 as of Sep 5, 2026 7-day low — no 7d data yet 30-day low $69.99 30-day change — baseline building Tracking since Sep 4, 2026 · 2 data points ## Price History 2 data points ### Vendors Selling Adamax BHG Labs shares common ownership with BodyHackGuide, and we earn a commission on purchases through our links. [ ![BHG Labs logo](https://bhglabs.co/store/wp-content/uploads/2026/06/logo-full.png) #### BHG Labs 4.8 1 listing · from $69.99 ](/vendor/bhg-labs) How we score these vendors Every supplier above is graded 0 to 100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank. [View Scorecard](/vendors/scorecard) ### Related Compounds [View All](/wiki) [ ### Adalank Nootropic Peptide Preclinical / Research compound Adalank is a hybrid research peptide combining structural elements of Adamax (the adamantyl-modified Semax analog) and Selank (the anxiolytic Pro-Gly-Pro tuftsin analog). t½ The commonly cited ~72-hour "functional duration" is an unverified community/vendor claim, not a measured value - no pharmacokinetic study of Adalank has ever been run. The figure is extrapolated from parent Adamax marketing claims. Actual serum half-life is unknown; there is no published PK data. 200-1200 mcg per dose (intranasal or subcutaneous), 1-2x daily Preclinical View Profile ](/compound/adalank)[ ### Cerebrolysin Nootropic Peptide Clinical Cerebrolysin is a porcine brain-derived peptide complex developed by EVER Neuro Pharma (Austria) — a low-molecular-weight neurotrophic preparation containing a mixture of free amino acids and bioactive peptides extracted from purified pig brain proteins. t½ ~2-4 hours (multi-component peptide mix) 85 PubMed View Profile ](/compound/cerebrolysin)[ ### Cortexin Nootropic Peptide Marketed in Russia/CIS (Geropharm); human clinical use with limited-quality evidence (small, mostly Russian-language studies; no Western RCT; not FDA/EMA approved) Cortexin is a purified peptide preparation extracted from cattle and pig cerebral cortex tissue — a low-molecular-weight neuropeptide complex used clinically in Russia and Eastern Europe for cognitive impairment, post-stroke recovery, encephalopathy, attention disorders, and pediatric developmental conditions. Like Cerebrolysin, Cortexin is positioned as a broad-spectrum neurotrophic preparation supplying bioactive peptides that mimic endogenous neurotrophic factors. t½ ~2-3 hours (estimated from analog peptide preparations) 18 PubMed View Profile ](/compound/cortexin)[ ### NA-Semax Nootropic Peptide Preclinical NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. t½ ~20-30 minutes (intranasal, estimated from analog data) 3 PubMed View Profile ](/compound/na-semax)[ ### NA-Semax Amidate Nootropic Peptide Preclinical NA-Semax Amidate is the C-terminally amidated NA-Semax — the carboxylic acid at the peptide's C-terminus is replaced with an amide group (-NH2), which is reported to further extend metabolic half-life by resisting carboxypeptidase cleavage in addition to the aminopeptidase resistance the N-acetyl group already provides. The practical effect is a peptide with dosing-frequency use: where standard Semax often requires 3-4 daily doses to maintain effect, NA-Semax Amidate is reported (in vendor monographs and community usage) to maintain subjective effects on a 1-2x daily schedule. t½ ~30-45 minutes (estimated, longer than standard Semax) 2 PubMed View Profile ](/compound/na-semax-amidate)[ ### P-21 Nootropic Peptide Preclinical P-21 is a synthetic cyclic dipeptide — Cyclo(L-prolyl-glycine) — derived from the Selank/Semax C-terminal Pro-Gly-Pro motif. t½ Not formally characterized in published work. P021 has only been studied in rodents (oral/dietary and subcutaneous dosing); no human pharmacokinetic data exist. 4 PubMed View Profile ](/compound/p21) [ View Full Dosage Guide → Protocols, calculator & safety for Adamax ](/guides/dosage/adamax) ### Related Articles [All Posts](/blog) [ #### BHG Labs review: a small, COA-backed nootropics and peptides vendor (2026) BHG Labs is a small, US-focused research-chemical vendor selling atomized nasal sprays, single-compound nootropic capsules, and lyophilized peptides, all lot-numbered and third-party COA-linked. Everything is research-use-only. The catalog is curated rather than huge, and there's no large public review history yet, so it suits experienced self-experimenters more than first-timers. Code REDDIT takes 10% off. 6/30/2026 ](/blog/bhg-labs-review)[ #### Ion Peptide Review 2026: BPC-157, GLP-1s, Buccal Strips & Bioregulators A complete look at Ion Peptide (ionpeptide.com), whose 92 products span research peptides, GLP-1 agonists, NAD+/B12/glutathione buccal strips, copper peptide topicals, Khavinson bioregulators, and PDRN. We cover pricing, testing, shipping, what they stock that others don't, and how they compare to other vendors on BodyHackGuide. 4/21/2026 ](/blog/ion-peptide-review-2026) ### Lowest Price per mg ![BHG Labs logo](https://bhglabs.co/store/wp-content/uploads/2026/06/logo-full.png) BHG Labs $69.99($7.00/mg) [Buy Now](https://bhglabs.co/product/adamax-10mg-atomized-solution/?ref=zmgqyxku&coupon=BHG20) BHG Labs shares common ownership with BodyHackGuide, and we earn a commission on purchases through our links. 1 vendors · 1 listings ### Research Score 60 0 PubMed results ### Quality Indicators Data Completeness 88% Description Mechanism of Action Chemical Data Dosing Protocols Safety Profile PubMed Results Interactions Vendor Listings ### Quick Facts Half-Life No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. Molecular Weight 1098.20 g/mol (calculated; awaiting MS confirmation) Administration Subcutaneous, Intranasal CAS Number Not assigned (research compound, no CAS registry entry as of 2026) Trial Phase Preclinical / Research compound ### Safety Profile Common Side Effects - • Mild headache during first 1-2 days of dosing (typically self-resolving) - • Transient irritability at doses above 1 mg - • Sleep onset delay if dosed in the evening - • Subcutaneous injection-site irritation [Full Dosage Guide](/guides/dosage/adamax)[Calculate Your Dose](/tools/reconstitution) Research Disclaimer This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use. ## Frequently Asked Questions Is Adamax just Semax with a chemistry tweak, or is it actually different? It's a structural derivative - Semax's Ac-MEHFPGP core plus an Ala-Gly tail capped with an adamantyl group borrowed from P-21. Same primary mechanism (BDNF / TrkB / D2 modulation), but the adamantane modification is hypothesized to improve blood-brain-barrier penetration and extend the subjective duration of effect to roughly 2-3 days vs Semax's ~30-60 minute serum half-life. No pharmacokinetic data exist for Adamax, so this is a community-reported difference in duration, not a measured one. The pharmacology is similar in kind, different in duration. Why are there no PubMed studies for Adamax? Adamax was first synthesized by Ceretropic (a research-peptide vendor) circa 2016, not a Russian academic institute, so it never entered the formal Semax / Selank publication pipeline. The Russian Institute of Molecular Genetics RAS is responsible for Semax and Selank - but they did not develop Adamax. Effects are extrapolated from Semax data and community reports; primary literature under the 'Adamax' name does not exist as of 2026. Intranasal or subcutaneous - which route do most researchers use? Both are documented. Subcutaneous is more common in current research protocols because the adamantyl tail makes the molecule larger and more lipophilic than parent Semax, which slows nasal absorption. Intranasal protocols exist but require higher doses to achieve comparable central effects. Subcutaneous at 500-1500 mcg every other day is the dominant community pattern. How does dosing schedule differ from Semax? Semax is typically dosed daily (often multiple times per day) because of its short serum half-life. Adamax community protocols describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; note there are no pharmacokinetic or receptor-occupancy data behind this. Daily dosing is not necessary and may increase the risk of D2 receptor desensitization without proportionate benefit. Can Adamax be stacked with Semax or P-21? Caution. All three modulate overlapping receptor systems (BDNF / TrkB / D2). Simultaneous full-dose stacking has not been characterized in any controlled setting and risks additive receptor desensitization. If combining, conservative low-dose protocols and longer washout windows between cycles are sensible. Adamax + Selank is a more common pairing because the mechanisms (BDNF / D2 vs GABAergic / serotonergic anxiolysis) are complementary rather than overlapping. What does an Adamax cycle look like end-to-end? A typical research cycle is 4-8 weeks with at least a 2-week washout. Beginners start at 500 mcg subcutaneous every other day to assess tolerance. Intermediate users move to 750-1000 mcg three times per week. Advanced protocols cap around 1500-2000 mcg every other day. Effects build over the first 1-2 weeks; subjective plateau is typically reported at weeks 3-4. Are there any known safety red flags? There are no formal toxicology studies. Anecdotal reports cite mild side effects similar to Semax: headache (often dose-related), transient insomnia if dosed in the evening, occasional irritability or mild mood elevation. No reports of serious adverse events in the public community datasets - but this reflects underreporting in unregulated use, not formal safety clearance. Avoid in pregnancy, lactation, active psychiatric instability, and uncontrolled hypertension. ## Research Tools [ ### Peptide Calculator Reconstitution & syringe units ](/tools/reconstitution)[ ### Reconstitution Guide How to mix, step by step ](/guides/how-to-reconstitute-peptides)[ ### Nasal Spray Calc mL per actuation ](/tools/intranasal)[ ### Half-Life Visualizer Decay curves ](/tools/halflife) ## Related Compounds [View All](/wiki) [ ### Adalank Nootropic Peptide Preclinical / Research compound Adalank is a hybrid research peptide combining structural elements of Adamax (the adamantyl-modified Semax analog) and Selank (the anxiolytic Pro-Gly-Pro tuftsin analog). t½ The commonly cited ~72-hour "functional duration" is an unverified community/vendor claim, not a measured value - no pharmacokinetic study of Adalank has ever been run. The figure is extrapolated from parent Adamax marketing claims. Actual serum half-life is unknown; there is no published PK data. 200-1200 mcg per dose (intranasal or subcutaneous), 1-2x daily Preclinical View Profile ](/compound/adalank)[ ### Cerebrolysin Nootropic Peptide Clinical Cerebrolysin is a porcine brain-derived peptide complex developed by EVER Neuro Pharma (Austria) — a low-molecular-weight neurotrophic preparation containing a mixture of free amino acids and bioactive peptides extracted from purified pig brain proteins. t½ ~2-4 hours (multi-component peptide mix) 85 PubMed View Profile ](/compound/cerebrolysin)[ ### Cortexin Nootropic Peptide Marketed in Russia/CIS (Geropharm); human clinical use with limited-quality evidence (small, mostly Russian-language studies; no Western RCT; not FDA/EMA approved) Cortexin is a purified peptide preparation extracted from cattle and pig cerebral cortex tissue — a low-molecular-weight neuropeptide complex used clinically in Russia and Eastern Europe for cognitive impairment, post-stroke recovery, encephalopathy, attention disorders, and pediatric developmental conditions. Like Cerebrolysin, Cortexin is positioned as a broad-spectrum neurotrophic preparation supplying bioactive peptides that mimic endogenous neurotrophic factors. t½ ~2-3 hours (estimated from analog peptide preparations) 18 PubMed View Profile ](/compound/cortexin)[ ### NA-Semax Nootropic Peptide Preclinical NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. t½ ~20-30 minutes (intranasal, estimated from analog data) 3 PubMed View Profile ](/compound/na-semax)[ ### NA-Semax Amidate Nootropic Peptide Preclinical NA-Semax Amidate is the C-terminally amidated NA-Semax — the carboxylic acid at the peptide's C-terminus is replaced with an amide group (-NH2), which is reported to further extend metabolic half-life by resisting carboxypeptidase cleavage in addition to the aminopeptidase resistance the N-acetyl group already provides. The practical effect is a peptide with dosing-frequency use: where standard Semax often requires 3-4 daily doses to maintain effect, NA-Semax Amidate is reported (in vendor monographs and community usage) to maintain subjective effects on a 1-2x daily schedule. t½ ~30-45 minutes (estimated, longer than standard Semax) 2 PubMed View Profile ](/compound/na-semax-amidate)[ ### P-21 Nootropic Peptide Preclinical P-21 is a synthetic cyclic dipeptide — Cyclo(L-prolyl-glycine) — derived from the Selank/Semax C-terminal Pro-Gly-Pro motif. t½ Not formally characterized in published work. P021 has only been studied in rodents (oral/dietary and subcutaneous dosing); no human pharmacokinetic data exist. 4 PubMed View Profile ](/compound/p21) ## Research Benches Reference pages that put Adamax next to the compounds people pair it with: roles, evidence, overlap and conflicts. No dosing. Research use only. [ Nasal Peptide Bench Selank and Adamax, with Semax as the comparison point research bench · no dosing ](/stack/nasal-peptide-bench) Free 2026 Peptide Cheat Sheet — 50 pages, PDF Reconstitution math, concentration charts, half-lives, and vendor trust tiers. The reference we wish we had on day one. [Download Free](/guides/peptide-cheat-sheet-download?utm_source=compound-adamax) ### Need bloodwork before starting? Full hormone + metabolic panels from Anabolic Insights. Code CHONCH for first-order discount. [Order Bloodwork](https://anabolicinsights.ai/?ref=nwm2zjb) ![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub — compound pricing, brain health protocols, dosing tools, and vendor reviews. 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