--- title: "Uridine Monophosphate vs Dihexa: Compared (2026)" url: https://www.bodyhackguide.co/compare/uridine-monophosphate-vs-dihexa description: "Compare Uridine Monophosphate vs Dihexa side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # Uridine Monophosphate (UMP) vs Dihexa Side-by-side comparison of Uridine Monophosphate (UMP) and Dihexa: mechanism, half-life, dose range, safety profile, and vendor pricing. Uridine Monophosphate (UMP): no price on file Dihexa from $79.99 ## Price snapshot ### Uridine Monophosphate (UMP) Current low — 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### Dihexa Current low $79.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## Uridine Monophosphate (UMP) Uridine monophosphate (UMP, also written 5'-UMP or uridine-5'-monophosphate) is the nucleotide form of uridine, consisting of the pyrimidine base uracil linked to a ribose sugar phosphorylated at the 5' position. It is… No vendor price on file. Full Uridine Monophosphate (UMP) profile (https://www.bodyhackguide.co/compound/uridine-monophosphate) ## Dihexa Dihexa is a synthetic peptide analogue of the angiotensin IV metabolite LVV-hemorphin-7, developed at Washington State University. It is considered one of the most potent cognitive enhancers ever tested in animal models… **Lowest listed price:** $79.99 across 3 listings Full Dihexa profile (https://www.bodyhackguide.co/compound/dihexa) ## Side-by-side comparison | Attribute | Uridine Monophosphate (UMP) | Dihexa | | --- | --- | --- | | Category | Nootropics | Nootropics | | Research Stage | Preclinical | Preclinical | | Mechanism of Action | Uridine monophosphate's mechanism of action as a nootropic is grounded in its role as a precursor for membrane phospholipid synthesis via the Kennedy pathway, with additional proposed effects on purinergic signalling, dopaminergic function, and synaptic… | Dihexa is a small-molecule analog derived from angiotensin IV (AngIV). It retains the Tyr-Ile core of Nle1-AngIV, with an N-terminal hexanoic acid cap and a C-terminal 6-aminohexanoic amide that give it metabolic stability and blood-brain-barrier penetration.… | | Half-Life | — | Not characterized in humans. Dihexa was engineered for metabolic stability (resistant to plasma and enzymatic degradation) and blood-brain-barrier penetration; in preclinical work its central procognitive effects appear to outlast its plasma presence. | | Typical Dose Range | — | 5 to 40 mg oral per day (anecdotal range; no established human dose) | | Dosing Frequency | — | Once daily (oral), typically in the morning | | Administration | — | Oral, Intranasal, Subcutaneous | | Side Effects | Uridine monophosphate has one of the most favourable safety profiles of any supplement in the nootropic space. It is a naturally occurring nutrient, present in human breast milk, liver, fish, and many other foods. Clinical trials with daily doses up to 2 grams… | No controlled human safety data. Anecdotal user reports include headache, fatigue, irritability or anxiety, insomnia, and vivid dreams, usually at higher doses. The most serious concern is theoretical rather than reported: because dihexa acts on the HGF/c-Met… | | Molecular Weight | 324.18 g/mol | 504.7 g/mol | | Common Vial Sizes | — | 50mg, 100mg | ## Price tracking Tracking Dihexa prices since September 5, 2026. Trend chart unlocks once we have price snapshots from more than one day. ### Uridine Monophosphate (UMP): potential benefits - D2/D3 receptor upregulation - Mood stabilization - Memory improvement - Synaptic plasticity - Neuronal membrane support - Long-term cognitive enhancement ### Dihexa: potential benefits - Synaptogenesis: formation of new dendritic spines and functional synapses (preclinical) - Memory and spatial-learning support in rodent models - Potential research application in Alzheimer's and other neurodegenerative disease models - HGF/c-Met and PI3K/Akt-linked neuroplasticity (mechanism proposed; key paper retracted) ## Frequently asked ### What's the difference between Uridine Monophosphate (UMP) and Dihexa? Uridine Monophosphate (UMP) is a nootropics that uridine monophosphate's mechanism of action as a nootropic is grounded in its role as a precursor for membrane phospholipid synthesis via the kennedy pathway, with additional…. Dihexa is a nootropics that dihexa is a small-molecule analog derived from angiotensin iv (angiv). it retains the tyr-ile core of nle1-angiv, with an n-terminal hexanoic acid cap and a c-terminal…. The two differ in mechanism, half-life (not reported vs Not characterized in humans. Dihexa was engineered for metabolic stability (resistant to plasma and enzymatic degradation) and blood-brain-barrier penetration; in preclinical work its central procognitive effects appear to outlast its plasma presence.), and typical dose range. ### Which has the longer half-life, Uridine Monophosphate (UMP) or Dihexa? Uridine Monophosphate (UMP) has a half-life of not reported. Dihexa has a half-life of Not characterized in humans. Dihexa was engineered for metabolic stability (resistant to plasma and enzymatic degradation) and blood-brain-barrier penetration; in preclinical work its central procognitive effects appear to outlast its plasma presence.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Can you stack Uridine Monophosphate (UMP) and Dihexa? Stacking depends on mechanism overlap, safety profile, and goals. Uridine Monophosphate (UMP) and Dihexa should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. Uridine Monophosphate (UMP) prices: https://www.bodyhackguide.co/compound/uridine-monophosphate?tab=prices Dihexa prices: https://www.bodyhackguide.co/compound/dihexa?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy Uridine Monophosphate (UMP) or Dihexa Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons Dihexa vs Noopept: https://www.bodyhackguide.co/compare/dihexa-vs-noopept **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks, and every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). 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