--- title: "Thymosin Alpha-1 vs ARA-290: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/thymosin-alpha-1-vs-ara-290 description: "Compare Thymosin Alpha-1 vs ARA-290 side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # Thymosin Alpha-1 (TA1) vs ARA-290 Side-by-side comparison of Thymosin Alpha-1 (TA1) and ARA-290: mechanism, half-life, dose range, safety profile, and vendor pricing. Thymosin Alpha-1 (TA1) from $39.99 ARA-290 from $32.00 ## Price snapshot ### Thymosin Alpha-1 (TA1) Current low $39.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### ARA-290 Current low $32.00 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## Thymosin Alpha-1 (TA1) Thymosin alpha-1 (Tα1) is a 28-amino-acid N-acetylated peptide (N-Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn) isolated and characterized by Allan… **Lowest listed price:** $39.99 across 4 listings Full Thymosin Alpha-1 (TA1) profile (https://www.bodyhackguide.co/compound/thymosin-alpha-1) ## ARA-290 ARA-290, also known as Cibinetide or pHBSP (Helix B Surface Peptide), is an 11-amino-acid peptide — QEQLERALNSS — designed to mimic a specific region of the tissue-protective surface of erythropoietin (EPO) without… **Lowest listed price:** $32.00 across 5 listings Full ARA-290 profile (https://www.bodyhackguide.co/compound/ara-290) ## Side-by-side comparison | Attribute | Thymosin Alpha-1 (TA1) | ARA-290 | | --- | --- | --- | | Category | Immune & Inflammation | Recovery | | Research Stage | Approved (International) | Phase 2 | | Mechanism of Action | Thymosin alpha-1 does not act through a single canonical receptor in the way many peptides do. Its mechanism is pleiotropic, involving pattern-recognition receptors, modulation of immune cell maturation and function, and shifts in cytokine signaling patterns.… | ARA-290's mechanism of action is one of the more elegantly engineered examples of pharmaceutical design in the peptide space. Understanding it requires appreciation of the dual-receptor biology of erythropoietin and the specific receptor-selective engineering… | | Half-Life | ~2 hours | ~2 minutes (plasma half-life; downstream tissue-protective effects persist hours to days) | | Typical Dose Range | 1,600 mcg (1.6 mg) per injection (standard clinical dose) | 1 mg - 4 mg subcutaneous daily | | Dosing Frequency | Twice weekly (subcutaneous) - the approved Zadaxin schedule; alternatively 900 mcg daily for intensive short-term courses | Once daily | | Administration | Subcutaneous | — | | Side Effects | Tα1 has one of the most benign side-effect profiles in the peptide space, supported by 45+ years of clinical experience in approved indications. Most users experience no acute side effects beyond mild injection site discomfort. Common (5-15% of users): -… | ARA-290 has demonstrated a notably favorable safety profile across clinical trials — one of the cleaner safety records among research peptides. The engineering rationale of separating tissue-protective effects from hematopoietic effects appears to have largely… | | Molecular Weight | 3108 Da | ~1257 Da | | Common Vial Sizes | 5mg, 10mg | — | ## Price History 3 data points - OF - Half Nattys - Disguised Alpha ## Price History 3 data points - Ion Peptide - BHG Labs - LB ### Thymosin Alpha-1 (TA1): potential benefits - Immune enhancement - Antiviral defense - Cancer adjuvant therapy - Autoimmune modulation - Vaccine potentiation ### ARA-290: potential benefits - Neuroprotective effects - Anti-inflammatory activity - Tissue repair without erythropoiesis - Potential diabetic neuropathy treatment - Sarcoidosis symptom reduction ## Frequently asked ### What's the difference between Thymosin Alpha-1 (TA1) and ARA-290? Thymosin Alpha-1 (TA1) is a immune & inflammation that thymosin alpha-1 does not act through a single canonical receptor in the way many peptides do. its mechanism is pleiotropic, involving pattern-recognition receptors, modulation of…. ARA-290 is a recovery that ara-290's mechanism of action is one of the more elegantly engineered examples of pharmaceutical design in the peptide space. understanding it requires appreciation of the…. The two differ in mechanism, half-life (~2 hours vs ~2 minutes (plasma half-life; downstream tissue-protective effects persist hours to days)), and typical dose range. ### Which has the longer half-life, Thymosin Alpha-1 (TA1) or ARA-290? Thymosin Alpha-1 (TA1) has a half-life of ~2 hours. ARA-290 has a half-life of ~2 minutes (plasma half-life; downstream tissue-protective effects persist hours to days). Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, Thymosin Alpha-1 (TA1) or ARA-290? Lowest listed price on BodyHackGuide: Thymosin Alpha-1 (TA1) from $39.99, ARA-290 from $32.00. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack Thymosin Alpha-1 (TA1) and ARA-290? Stacking depends on mechanism overlap, safety profile, and goals. Thymosin Alpha-1 (TA1) and ARA-290 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. Thymosin Alpha-1 (TA1) prices: https://www.bodyhackguide.co/compound/thymosin-alpha-1?tab=prices ARA-290 prices: https://www.bodyhackguide.co/compound/ara-290?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy Thymosin Alpha-1 (TA1) or ARA-290 Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons Thymosin-Alpha-1 vs BPC-157: https://www.bodyhackguide.co/compare/thymosin-alpha-1-vs-bpc-157 TB-500 vs Thymosin-Alpha-1: https://www.bodyhackguide.co/compare/tb-500-vs-thymosin-alpha-1 LL-37 vs Thymosin-Alpha-1: https://www.bodyhackguide.co/compare/ll-37-vs-thymosin-alpha-1 **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). BodyHackGuide (https://www.bodyhackguide.co/) Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology). 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