--- title: "Tesamorelin vs 5-Amino-1MQ: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/tesamorelin-vs-5-amino-1mq description: "Compare Tesamorelin vs 5-Amino-1MQ side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # Tesamorelin vs 5-Amino-1MQ Side-by-side comparison of Tesamorelin and 5-Amino-1MQ: mechanism, half-life, dose range, safety profile, and vendor pricing. Tesamorelin from $44.99 5-Amino-1MQ from $29.99 ## Price snapshot ### Tesamorelin Current low $44.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### 5-Amino-1MQ Current low $29.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## Tesamorelin Tesamorelin is a stabilized synthetic analog of human growth hormone-releasing hormone (GHRH) — specifically the full 44-amino-acid GHRH sequence with a single N-terminal trans-3-hexenoyl fatty-acid modification. That… **Lowest listed price:** $44.99 across 5 listings Full Tesamorelin profile (https://www.bodyhackguide.co/compound/tesamorelin) ## 5-Amino-1MQ 5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to… **Lowest listed price:** $29.99 across 14 listings Full 5-Amino-1MQ profile (https://www.bodyhackguide.co/compound/5-amino-1mq) ## Side-by-side comparison | Attribute | Tesamorelin | 5-Amino-1MQ | | --- | --- | --- | | Category | Growth Hormone / IGF-1 Axis | Weight Loss | | Research Stage | FDA Approved | Preclinical | | Mechanism of Action | Tesamorelin activates the same GHRH receptor (GHRHR) as endogenous GHRH and CJC-1295 / MOD-GRF 1-29, but with a distinct pharmacokinetic profile driven by its trans-3-hexenoyl N-terminal modification. 1. GHRH receptor agonism (Gs / cAMP / PKA / CREB pathway) -… | 5-Amino-1MQ works by inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to the nitrogen of nicotinamide (vitamin B3 amide), producing 1-methylnicotinamide (1-MNA) and… | | Half-Life | 8 to 11 minutes in healthy subjects (EGRIFTA SV and EGRIFTA WR labels) | ~6–12 hours (oral) | | Typical Dose Range | 1,000–2,000 mcg (1–2 mg) daily | 50 mg - 150 mg daily (oral or injection) | | Dosing Frequency | Once daily subcutaneous injection | Once daily oral | | Administration | subcutaneous | Oral | | Side Effects | Tesamorelin has a well-characterized side-effect profile from the FDA approval program, which is a significant advantage over non-approved GHRH analogs. Common (10% in Phase 3 trials) - Injection site reactions — erythema, pruritus, pain at site; most frequent… | The side effect profile of 5-amino-1MQ in humans is not documented because there are no human clinical trials. Rodent studies report generally good tolerability at doses producing metabolic and muscle benefits, without obvious signs of hepatotoxicity,… | | Molecular Weight | 5135.9 Da | 159.21 g/mol | | Common Vial Sizes | 2mg, 10mg | 50mg capsules, 100mg capsules | ## Price History 3 data points - BM - Half Nattys - BHG Labs ## Price History 5 data points - OF - BM - Half Nattys - Ion Peptide - Disguised Alpha - RC - LB ### Tesamorelin: potential benefits - Reduction of visceral adipose tissue (~15% at 26 weeks in the pivotal HIV trial; FDA-label indication) - Reduction of hepatic fat content (NAFLD off-label indication) - Higher IGF-1 (mean rise of about 81% at 26 weeks in the main Phase 3 trial, PMID 18057338) - Preserved pulsatile GH release (vs continuous elevation with CJC-1295-DAC) - Improved body composition (VAT down, lean mass preserved) - Sustained VAT reduction through 52 weeks with continued dosing - FDA-approved - the only GHRH secretagogue with that status ### 5-Amino-1MQ: potential benefits - Enhanced fat metabolism and weight loss - Increased NAD+ levels in adipose tissue - Improved cellular energy production - Anti-aging properties via sirtuin activation ## Frequently asked ### What's the difference between Tesamorelin and 5-Amino-1MQ? Tesamorelin is a growth hormone / igf-1 axis that tesamorelin activates the same ghrh receptor (ghrhr) as endogenous ghrh and cjc-1295 / mod-grf 1-29, but with a distinct pharmacokinetic profile driven by its trans-3-hexenoyl…. 5-Amino-1MQ is a weight loss that 5-amino-1mq works by inhibiting nicotinamide n-methyltransferase (nnmt), an enzyme that catalyzes the transfer of a methyl group from s-adenosyl-l-methionine (sam) to the nitrogen…. The two differ in mechanism, half-life (8 to 11 minutes in healthy subjects (EGRIFTA SV and EGRIFTA WR labels) vs ~6–12 hours (oral)), and typical dose range. ### Which has the longer half-life, Tesamorelin or 5-Amino-1MQ? Tesamorelin has a half-life of 8 to 11 minutes in healthy subjects (EGRIFTA SV and EGRIFTA WR labels). 5-Amino-1MQ has a half-life of ~6–12 hours (oral). Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, Tesamorelin or 5-Amino-1MQ? Lowest listed price on BodyHackGuide: Tesamorelin from $44.99, 5-Amino-1MQ from $29.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack Tesamorelin and 5-Amino-1MQ? Stacking depends on mechanism overlap, safety profile, and goals. Tesamorelin and 5-Amino-1MQ should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. Tesamorelin prices: https://www.bodyhackguide.co/compound/tesamorelin?tab=prices 5-Amino-1MQ prices: https://www.bodyhackguide.co/compound/5-amino-1mq?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy Tesamorelin or 5-Amino-1MQ Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons 5-Amino-1MQ vs Tirzepatide: https://www.bodyhackguide.co/compare/5-amino-1mq-vs-tirzepatide Tesamorelin vs CJC-1295: https://www.bodyhackguide.co/compare/tesamorelin-vs-cjc-1295 Tesamorelin vs Sermorelin: https://www.bodyhackguide.co/compare/tesamorelin-vs-sermorelin **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). BodyHackGuide (https://www.bodyhackguide.co/) Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology). Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. - Terms: https://www.bodyhackguide.co/terms - Privacy: https://www.bodyhackguide.co/privacy ## Structured data ```json [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compare", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "Tesamorelin vs 5-Amino-1MQ" } ] }, { "@context": "https://schema.org", "@type": "WebPage", "name": "Tesamorelin vs 5-Amino-1MQ: Side-by-Side Comparison (2026)", "description": "Compare Tesamorelin vs 5-Amino-1MQ side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices.", "url": "https://www.bodyhackguide.co/compare/tesamorelin-vs-5-amino-1mq", "dateModified": "2026-10-28", "isPartOf": { "@type": "WebSite", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" }, "mainEntity": { "@type": "ItemList", "itemListElement": [ { "@type": "ListItem", "position": 1, "item": { "@type": "Product", "name": "Tesamorelin", "description": "Tesamorelin is a stabilized synthetic analog of human growth hormone-releasing hormone (GHRH) — specifically the full 44-amino-acid GHRH sequence with a single N-terminal trans-3-hexenoyl fatty-acid modification. That modification protects the peptide from rapid dipeptidyl peptidase-4 (DPP-4)…", "url": "https://www.bodyhackguide.co/compound/tesamorelin", "category": "Growth Hormone / IGF-1 Axis", "offers": { "@type": "AggregateOffer", "lowPrice": "44.99", "priceCurrency": "USD", "offerCount": 5 } } }, { "@type": "ListItem", "position": 2, "item": { "@type": "Product", "name": "5-Amino-1MQ", "description": "5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to form 1-methylnicotinamide (1-MNA) and S-adenosyl-L-homocysteine (SAH). The compound…", "url": "https://www.bodyhackguide.co/compound/5-amino-1mq", "category": "Weight Loss", "offers": { "@type": "AggregateOffer", "lowPrice": "29.99", "priceCurrency": "USD", "offerCount": 14 } } } ] } }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 273 compound profiles, interactive dosing calculators, vendor price comparisons, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. We earn a commission on purchases through some of our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What's the difference between Tesamorelin and 5-Amino-1MQ?", "acceptedAnswer": { "@type": "Answer", "text": "Tesamorelin is a growth hormone / igf-1 axis that tesamorelin activates the same ghrh receptor (ghrhr) as endogenous ghrh and cjc-1295 / mod-grf 1-29, but with a distinct pharmacokinetic profile driven by its trans-3-hexenoyl…. 5-Amino-1MQ is a weight loss that 5-amino-1mq works by inhibiting nicotinamide n-methyltransferase (nnmt), an enzyme that catalyzes the transfer of a methyl group from s-adenosyl-l-methionine (sam) to the nitrogen…. The two differ in mechanism, half-life (8 to 11 minutes in healthy subjects (EGRIFTA SV and EGRIFTA WR labels) vs ~6–12 hours (oral)), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, Tesamorelin or 5-Amino-1MQ?", "acceptedAnswer": { "@type": "Answer", "text": "Tesamorelin has a half-life of 8 to 11 minutes in healthy subjects (EGRIFTA SV and EGRIFTA WR labels). 5-Amino-1MQ has a half-life of ~6–12 hours (oral). Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Which is cheaper, Tesamorelin or 5-Amino-1MQ?", "acceptedAnswer": { "@type": "Answer", "text": "Lowest listed price on BodyHackGuide: Tesamorelin from $44.99, 5-Amino-1MQ from $29.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers." } }, { "@type": "Question", "name": "Can you stack Tesamorelin and 5-Amino-1MQ?", "acceptedAnswer": { "@type": "Answer", "text": "Stacking depends on mechanism overlap, safety profile, and goals. Tesamorelin and 5-Amino-1MQ should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds." } } ] } ] ```