--- title: "SLU-PP-332 vs MOTS-c: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/slu-pp-332-vs-mots-c description: "Compare SLU-PP-332 vs MOTS-c side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # SLU-PP-332 vs MOTS-c Side-by-side comparison of SLU-PP-332 and MOTS-c: mechanism, half-life, dose range, safety profile, and vendor pricing. SLU-PP-332 from $69.99 MOTS-c from $44.99 ## Price snapshot ### SLU-PP-332 Current low $69.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### MOTS-c Current low $44.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## SLU-PP-332 SLU-PP-332 is the first-generation synthetic pan-agonist of the estrogen-related receptors (ERRα, ERRβ, ERRγ) developed by the laboratory of Thomas Burris at Saint Louis University and reported in a landmark 2023… **Lowest listed price:** $69.99 across 5 listings Full SLU-PP-332 profile (https://www.bodyhackguide.co/compound/slu-pp-332) ## MOTS-c MOTS-c (Mitochondrial ORF of the Twelve S rRNA type-c) is a 16-amino-acid mitochondrial-derived peptide — a member of a recently discovered class of small peptides encoded in mitochondrial DNA rather than nuclear DNA. It… **Lowest listed price:** $44.99 across 8 listings Full MOTS-c profile (https://www.bodyhackguide.co/compound/mots-c) ## Side-by-side comparison | Attribute | SLU-PP-332 | MOTS-c | | --- | --- | --- | | Category | Performance | Longevity & Cellular Health | | Research Stage | Preclinical | Preclinical | | Mechanism of Action | SLU-PP-332 acts through pan-agonism of the three estrogen-related receptors (ERRα/NR3B1, ERRβ/NR3B2, ERRγ/NR3B3), a subfamily of orphan nuclear receptors that regulate oxidative metabolism, mitochondrial biogenesis, and exercise-responsive gene expression. The… | A New Class of Signaling Molecule MOTS-c belongs to the mitochondrial-derived peptides (MDPs) - a class of small peptides encoded within mitochondrial DNA open reading frames that were historically thought to encode only ribosomal RNAs. The known MDPs include:… | | Half-Life | — | ~4–6 hours | | Typical Dose Range | Research compound — no established human doses. Animal studies: 10-50 mg/kg | 5,000–10,000 mcg (5–10 mg) per injection | | Dosing Frequency | — | 2-3 times per week | | Administration | — | Subcutaneous, Intramuscular | | Side Effects | The side effect profile of SLU-PP-332 in humans is undocumented because no clinical trials have been conducted. Rodent studies report generally acceptable tolerability at doses producing exercise-mimetic metabolic effects, without overt signs of toxicity on… | Reported Effects (limited human data) - Injection site reactions — Mild erythema, transient itching at SC injection site. Site rotation minimizes. Probably the single most reported issue. - Transient fatigue — Some users report mild fatigue in the first week… | | Molecular Weight | 290.3 g/mol | 2174 Da | | Common Vial Sizes | — | 5mg, 10mg | ## Price History 3 data points - Half Nattys - Ion Peptide - BHG Labs ## Price History 4 data points - OF - BM - Half Nattys - Ion Peptide - BHG Labs ### SLU-PP-332: potential benefits - Exercise mimicry without physical exertion - Enhanced fat oxidation - Increased mitochondrial biogenesis - Improved endurance capacity - Muscle fiber type conversion - Metabolic health improvement ### MOTS-c: potential benefits - Insulin sensitivity - Exercise mimicry - Metabolic health - Anti-aging - Fat oxidation - Longevity ## Frequently asked ### What's the difference between SLU-PP-332 and MOTS-c? SLU-PP-332 is a performance that slu-pp-332 acts through pan-agonism of the three estrogen-related receptors (errα/nr3b1, errβ/nr3b2, errγ/nr3b3), a subfamily of orphan nuclear receptors that regulate oxidative…. MOTS-c is a longevity & cellular health that a new class of signaling molecule mots-c belongs to the mitochondrial-derived peptides (mdps) - a class of small peptides encoded within mitochondrial dna open reading frames that…. The two differ in mechanism, half-life (not reported vs ~4–6 hours), and typical dose range. ### Which has the longer half-life, SLU-PP-332 or MOTS-c? SLU-PP-332 has a half-life of not reported. MOTS-c has a half-life of ~4–6 hours. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, SLU-PP-332 or MOTS-c? Lowest listed price on BodyHackGuide: SLU-PP-332 from $69.99, MOTS-c from $44.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack SLU-PP-332 and MOTS-c? Stacking depends on mechanism overlap, safety profile, and goals. SLU-PP-332 and MOTS-c should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. SLU-PP-332 prices: https://www.bodyhackguide.co/compound/slu-pp-332?tab=prices MOTS-c prices: https://www.bodyhackguide.co/compound/mots-c?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy SLU-PP-332 or MOTS-c Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons MOTS C vs SS-31: https://www.bodyhackguide.co/compare/mots-c-vs-ss-31 Methylene Blue vs MOTS C: https://www.bodyhackguide.co/compare/methylene-blue-vs-mots-c MOTS C vs NMN: https://www.bodyhackguide.co/compare/mots-c-vs-nmn **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). BodyHackGuide (https://www.bodyhackguide.co/) Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology). Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. - Terms: https://www.bodyhackguide.co/terms - Privacy: https://www.bodyhackguide.co/privacy ## Structured data ```json [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compare", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "SLU-PP-332 vs MOTS-c" } ] }, { "@context": "https://schema.org", "@type": "WebPage", "name": "SLU-PP-332 vs MOTS-c: Side-by-Side Comparison (2026)", "description": "Compare SLU-PP-332 vs MOTS-c side by side. We earn a commission on some vendor links. 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