--- title: "Semax/Selank Blend vs N-Acetyl-Selank: Compared (2026)" url: https://www.bodyhackguide.co/compare/semax-selank-blend-vs-n-acetyl-selank description: "Compare Semax/Selank Blend vs N-Acetyl-Selank side by side. We earn a commission on some vendor links. Mechanism, half-life and side effects." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # Semax/Selank Blend vs N-Acetyl-Selank Side-by-side comparison of Semax/Selank Blend and N-Acetyl-Selank: mechanism, half-life, dose range, safety profile, and vendor pricing. Semax/Selank Blend from $74.99 N-Acetyl-Selank from $79.99 ## Price snapshot ### Semax/Selank Blend Current low $74.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### N-Acetyl-Selank Current low $79.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## Semax/Selank Blend Combined nootropic and anxiolytic peptide blend **Lowest listed price:** $74.99 across 3 listings Full Semax/Selank Blend profile (https://www.bodyhackguide.co/compound/semax-selank-blend) ## N-Acetyl-Selank N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a tuftsin-derived heptapeptide used intranasally for its reported anxiolytic and nootropic effects. The acetyl group is claimed to improve stability and… **Lowest listed price:** $79.99 across 2 listings Full N-Acetyl-Selank profile (https://www.bodyhackguide.co/compound/n-acetyl-selank) ## Side-by-side comparison | Attribute | Semax/Selank Blend | N-Acetyl-Selank | | --- | --- | --- | | Category | Nootropics | Cognitive | | Research Stage | Preclinical (no trials on the blend; components studied separately, mostly in Russia) | Preclinical (the N-acetyl analog has no dedicated studies); parent Selank has limited clinical use in Russia | | Mechanism of Action | The Semax/Selank blend combines two synthetic Russian-developed regulatory heptapeptides, dosed together (usually intranasally) to pair an activating, pro-cognitive peptide with a calming, anxiolytic one. Because the blend itself has never been studied, its… | N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunopeptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro tail added to slow enzymatic breakdown.… | | Half-Life | Both component peptides have short plasma half-lives (on the order of minutes) but a prolonged duration of central action, attributed to the protective C-terminal Pro-Gly-Pro sequence they share. Blend-specific pharmacokinetics have not been characterized. | Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature. | | Typical Dose Range | Semax ~250-600 mcg + Selank ~250-300 mcg per day, intranasal (community-reported; no established blend dose) | 100-900 mcg | | Dosing Frequency | Once or twice daily, intranasal (community practice; no validated schedule for the blend) | Once or twice daily (intranasal); some advanced users split into 2-3 doses | | Administration | — | — | | Side Effects | Reported side effects are drawn from single-component use, since the blend itself has not been studied. Intranasal administration can cause nasal or throat irritation and mild headache. The Semax component may, at higher doses, cause over-stimulation,… | In short Russian clinical trials, parent Selank was generally well tolerated with no serious adverse effects reported [PMID:18454096]. Reported or plausible effects (largely extrapolated to the analog): mild nasal irritation or congestion from the spray,… | | Molecular Weight | — | ~793.9 g/mol (theoretical: Selank ~751.9 g/mol + N-terminal acetyl, ~+42). Approximate molecular formula C35H59N11O10. | | Common Vial Sizes | — | — | ## Price History 2 data points - Half Nattys - Disguised Alpha ## Price tracking Tracking N-Acetyl-Selank prices since September 5, 2026. Trend chart unlocks once we have price snapshots from more than one day. ### Semax/Selank Blend: potential benefits - Focus, clarity, and verbal fluency attributed to the Semax component (linked to BDNF/TrkB neurotrophic signaling in preclinical studies) - Calming, anti-anxiety effects attributed to the Selank component (a GABA-modulating, anxiolytic peptide in animal and limited clinical studies) - 'Calm focus' - the community rationale of pairing an activating peptide with an anxiolytic one to get drive without jitters - Anecdotal stress resilience and mood support - Reported memory and learning support (component-level preclinical signals only; not demonstrated for the blend) ### N-Acetyl-Selank: potential benefits - Anxiolytic (calming) effects - the most-studied action of parent Selank, including a Russian clinical trial in generalized anxiety disorder [PMID:18454096] - Nootropic / cognitive support - reported attention and memory benefits in rodent models, linked to BDNF changes [PMID:31625062] - Stress resilience reported without the sedation, tolerance, or dependence typically seen with benzodiazepines (preclinical framing) [PMID:30255741] - Possible support during withdrawal states (alcohol, opioid) in animal models [PMID:24913576][PMID:36322304] - Claimed longer duration vs. plain Selank from N-terminal acetylation - a community/vendor claim not verified in published data ## Frequently asked ### What's the difference between Semax/Selank Blend and N-Acetyl-Selank? Semax/Selank Blend is a nootropics that the semax/selank blend combines two synthetic russian-developed regulatory heptapeptides, dosed together (usually intranasally) to pair an activating, pro-cognitive peptide with a…. N-Acetyl-Selank is a cognitive that n-acetyl-selank is the n-terminally acetylated analog of selank, a synthetic heptapeptide (thr-lys-pro-arg-pro-gly-pro) derived from the endogenous immunopeptide tuftsin…. The two differ in mechanism, half-life (Both component peptides have short plasma half-lives (on the order of minutes) but a prolonged duration of central action, attributed to the protective C-terminal Pro-Gly-Pro sequence they share. Blend-specific pharmacokinetics have not been characterized. vs Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature.), and typical dose range. ### Which has the longer half-life, Semax/Selank Blend or N-Acetyl-Selank? Semax/Selank Blend has a half-life of Both component peptides have short plasma half-lives (on the order of minutes) but a prolonged duration of central action, attributed to the protective C-terminal Pro-Gly-Pro sequence they share. Blend-specific pharmacokinetics have not been characterized.. N-Acetyl-Selank has a half-life of Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, Semax/Selank Blend or N-Acetyl-Selank? Lowest listed price on BodyHackGuide: Semax/Selank Blend from $74.99, N-Acetyl-Selank from $79.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack Semax/Selank Blend and N-Acetyl-Selank? Stacking depends on mechanism overlap, safety profile, and goals. Semax/Selank Blend and N-Acetyl-Selank should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. Semax/Selank Blend prices: https://www.bodyhackguide.co/compound/semax-selank-blend?tab=prices N-Acetyl-Selank prices: https://www.bodyhackguide.co/compound/n-acetyl-selank?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy Semax/Selank Blend or N-Acetyl-Selank Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons N Acetyl Selank vs N Acetyl Semax: https://www.bodyhackguide.co/compare/n-acetyl-selank-vs-n-acetyl-semax **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. 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N-Acetyl-Selank is a cognitive that n-acetyl-selank is the n-terminally acetylated analog of selank, a synthetic heptapeptide (thr-lys-pro-arg-pro-gly-pro) derived from the endogenous immunopeptide tuftsin…. The two differ in mechanism, half-life (Both component peptides have short plasma half-lives (on the order of minutes) but a prolonged duration of central action, attributed to the protective C-terminal Pro-Gly-Pro sequence they share. Blend-specific pharmacokinetics have not been characterized. vs Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. 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