--- title: "Selank vs Noopept: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/selank-vs-noopept description: "Compare Selank vs Noopept side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # Selank vs Noopept Side-by-side comparison of Selank and Noopept: mechanism, half-life, dose range, safety profile, and vendor pricing. Selank from $25.00 Noopept from $49.99 ## Price snapshot ### Selank Current low $25.00 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### Noopept Current low $49.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## Selank Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro, 750 Da molecular weight) developed in the 1990s at the Institute of Molecular Genetics of the Russian Academy of Sciences as a synthetic analog of tuftsin… **Lowest listed price:** $25.00 across 6 listings Full Selank profile (https://www.bodyhackguide.co/compound/selank) ## Noopept Noopept is the common brand and research name for N-phenylacetyl-L-prolylglycine ethyl ester (GVS-111; INN omberacetam), a small dipeptide nootropic developed in the 1990s at the Russian Academy of Medical Sciences'… **Lowest listed price:** $49.99 across 1 listing Full Noopept profile (https://www.bodyhackguide.co/compound/noopept) ## Side-by-side comparison | Attribute | Selank | Noopept | | --- | --- | --- | | Category | Nootropics | Nootropics | | Research Stage | Approved (Russia, as anxiolytic and nootropic medication) | Approved (Russia) | | Mechanism of Action | Primary Mechanism: Multi-System Neurochemical Modulation Selank does not have a single clean receptor-binding mechanism. Unlike benzodiazepines (GABA-A positive allosteric modulators), SSRIs (serotonin reuptake inhibition), or buspirone (5-HT1A partial… | Noopept's mechanism of action is multifaceted and — despite decades of research — incompletely understood. Several convergent pathways have been proposed, each supported by preclinical data but none definitively established as the primary driver of its… | | Half-Life | ~2-3 minutes plasma half-life (functional anxiolytic and nootropic effects persist 12-24 hours due to gene expression and neurotransmitter modulation) | — | | Typical Dose Range | 250-750 mcg intranasal daily (0.15% solution: 2-3 drops per nostril 2-3x daily); typical course is 14-21 days | — | | Dosing Frequency | Intranasal 1–3 times daily | — | | Administration | Intranasal | — | | Side Effects | Overall Safety Profile Selank has one of the best safety profiles in the anxiolytic space. Over 15+ years of Russian clinical use and research, the compound has been associated with essentially no serious adverse events at therapeutic doses. This compares… | Noopept is generally well tolerated in the Russian clinical literature, with side effects that are typically mild and transient. However, "well tolerated in Russian open-label trials" is a weaker safety claim than the rigorous multi-phase trial data underlying… | | Molecular Weight | 751.9 Da | 318.37 g/mol | | Common Vial Sizes | 5mg, 10mg | — | ## Price History 5 data points - OF - Half Nattys - Ion Peptide - BHG Labs ## Price History 2 data points ### Selank: potential benefits - Anxiolytic effects comparable to benzodiazepines but without sedation or dependence in Russian clinical trials (PMID: 18454096) - Positive allosteric modulation of brain GABA receptors through a non-benzodiazepine binding site (PMID: 30255741) - Immunomodulation via Th1/Th2 cytokine balance and IL-6 regulation in patients with anxiety-asthenic disorders (PMID: 18577961) - Cognitive and memory support linked to BDNF upregulation in the hippocampus in preclinical models (PMID: 18841804) - Modulation of the endogenous enkephalin-opioid system supporting mood and stress tolerance (PMID: 22550852) - Anti-inflammatory and adaptogenic effects through normalization of stress-induced cytokine dysregulation - Non-addictive anxiolytic profile - no tolerance, withdrawal, or dependence reported across years of Russian clinical use ### Noopept: potential benefits - Memory enhancement - BDNF/NGF upregulation - Neuroprotection - Focus and learning speed - Anxiety reduction (moderate) - Anti-amyloid properties ## Frequently asked ### What's the difference between Selank and Noopept? Selank is a nootropics that primary mechanism: multi-system neurochemical modulation selank does not have a single clean receptor-binding mechanism. unlike benzodiazepines (gaba-a positive allosteric…. Noopept is a nootropics that noopept's mechanism of action is multifaceted and — despite decades of research — incompletely understood. several convergent pathways have been proposed, each supported by…. The two differ in mechanism, half-life (~2-3 minutes plasma half-life (functional anxiolytic and nootropic effects persist 12-24 hours due to gene expression and neurotransmitter modulation) vs not reported), and typical dose range. ### Which has the longer half-life, Selank or Noopept? Selank has a half-life of ~2-3 minutes plasma half-life (functional anxiolytic and nootropic effects persist 12-24 hours due to gene expression and neurotransmitter modulation). Noopept has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, Selank or Noopept? Lowest listed price on BodyHackGuide: Selank from $25.00, Noopept from $49.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack Selank and Noopept? Stacking depends on mechanism overlap, safety profile, and goals. Selank and Noopept should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. Selank prices: https://www.bodyhackguide.co/compound/selank?tab=prices Noopept prices: https://www.bodyhackguide.co/compound/noopept?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy Selank or Noopept Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons Selank vs Semax: https://www.bodyhackguide.co/compare/selank-vs-semax Noopept vs Piracetam: https://www.bodyhackguide.co/compare/noopept-vs-piracetam Selank vs Phenibut: https://www.bodyhackguide.co/compare/selank-vs-phenibut Dihexa vs Noopept: https://www.bodyhackguide.co/compare/dihexa-vs-noopept **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). BodyHackGuide (https://www.bodyhackguide.co/) Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology). Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. 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