--- title: "RU-58841 vs AHK-Cu: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/ru-58841-vs-ahk-cu description: "Compare RU-58841 vs AHK-Cu side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # RU-58841 vs AHK-Cu Side-by-side comparison of RU-58841 and AHK-Cu: mechanism, half-life, dose range, safety profile, and vendor pricing. RU-58841 from $49.99 AHK-Cu from $44.99 ## Price snapshot ### RU-58841 Current low $49.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### AHK-Cu Current low $44.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## RU-58841 RU-58841 (also known as PSK-3841 or HMR-3841, and commonly written simply as RU in hair-loss forums) is a non-steroidal androgen receptor antagonist originally developed by Roussel Uclaf (later absorbed into Sanofi) in… **Lowest listed price:** $49.99 across 2 listings Full RU-58841 profile (https://www.bodyhackguide.co/compound/ru-58841) ## AHK-Cu AHK-Cu (Ala-His-Lys-Copper) is a copper chelating tripeptide related to but distinct from GHK-Cu (Gly-His-Lys-Copper). Where GHK-Cu is the most-studied copper peptide and naturally occurs in human plasma, AHK-Cu is a… **Lowest listed price:** $44.99 across 5 listings Full AHK-Cu profile (https://www.bodyhackguide.co/compound/ahk-cu) ## Side-by-side comparison | Attribute | RU-58841 | AHK-Cu | | --- | --- | --- | | Category | Other | Skin & Hair | | Research Stage | Preclinical | Preclinical | | Mechanism of Action | RU-58841 is a non-steroidal androgen receptor (AR) antagonist with a chemical structure unrelated to testosterone, DHT, or the steroidal antiandrogens (cyproterone acetate, spironolactone). Its pharmacology was characterized in the early 1990s by teams at… | AHK-Cu delivers bioavailable copper ions to follicular and dermal tissues. Copper acts as a cofactor for lysyl oxidase (collagen/elastin crosslinking), superoxide dismutase (antioxidant), and vascular endothelial growth factor (VEGF) signaling. The tripeptide… | | Half-Life | — | Unknown (topical half-life, follicular retention not well characterized) | | Typical Dose Range | 25 mg - 50 mg topical daily (dissolved in vehicle) | — | | Dosing Frequency | — | once_daily | | Administration | — | Topical, Subcutaneous, Intradermal | | Side Effects | The side-effect profile of RU-58841 is not formally characterized in humans. What follows is a synthesis of the preclinical literature, the limited phase I human data, user-reported outcomes from hair-loss forums, and mechanistic inference from the broader… | — | | Molecular Weight | 369.34 g/mol | Free peptide (AHK): 354.41 Da (C15H26N6O4). Copper complex (AHK-Cu): 415.9 Da (C15H24CuN6O4, neutral 1:1 Cu(II) complex - Cu(II) displaces two protons from the tripeptide ligand). | | Common Vial Sizes | — | 50, 100 | ## Price History 2 data points - Half Nattys - Disguised Alpha ## Price History 2 data points - Ion Peptide - Disguised Alpha ### RU-58841: potential benefits - Prevention of hair follicle miniaturization - Hair loss reduction (androgenic alopecia) - Topical application minimizes systemic effects - Alternative to finasteride without systemic 5-AR inhibition ### AHK-Cu: potential benefits - Hair follicle stimulation — activates anagen phase via Wnt/β-catenin in dermal papilla cells - Reduction of follicle miniaturization in androgenetic alopecia models - Enhanced scalp vascularity via VEGF upregulation - Wound healing acceleration — copper cofactor for lysyl oxidase and collagen maturation - Synergistic with GHK-Cu in multi-peptide scalp formulations ## Frequently asked ### What's the difference between RU-58841 and AHK-Cu? RU-58841 is a other that ru-58841 is a non-steroidal androgen receptor (ar) antagonist with a chemical structure unrelated to testosterone, dht, or the steroidal antiandrogens (cyproterone acetate,…. AHK-Cu is a skin & hair that ahk-cu delivers bioavailable copper ions to follicular and dermal tissues. copper acts as a cofactor for lysyl oxidase (collagen/elastin crosslinking), superoxide dismutase…. The two differ in mechanism, half-life (not reported vs Unknown (topical half-life, follicular retention not well characterized)), and typical dose range. ### Which has the longer half-life, RU-58841 or AHK-Cu? RU-58841 has a half-life of not reported. AHK-Cu has a half-life of Unknown (topical half-life, follicular retention not well characterized). Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, RU-58841 or AHK-Cu? Lowest listed price on BodyHackGuide: RU-58841 from $49.99, AHK-Cu from $44.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack RU-58841 and AHK-Cu? Stacking depends on mechanism overlap, safety profile, and goals. RU-58841 and AHK-Cu should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. RU-58841 prices: https://www.bodyhackguide.co/compound/ru-58841?tab=prices AHK-Cu prices: https://www.bodyhackguide.co/compound/ahk-cu?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy RU-58841 or AHK-Cu Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons GHK CU vs AHK CU: https://www.bodyhackguide.co/compare/ghk-cu-vs-ahk-cu **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). BodyHackGuide (https://www.bodyhackguide.co/) Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology). Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. 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AHK-Cu is a skin & hair that ahk-cu delivers bioavailable copper ions to follicular and dermal tissues. copper acts as a cofactor for lysyl oxidase (collagen/elastin crosslinking), superoxide dismutase…. The two differ in mechanism, half-life (not reported vs Unknown (topical half-life, follicular retention not well characterized)), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, RU-58841 or AHK-Cu?", "acceptedAnswer": { "@type": "Answer", "text": "RU-58841 has a half-life of not reported. AHK-Cu has a half-life of Unknown (topical half-life, follicular retention not well characterized). Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Which is cheaper, RU-58841 or AHK-Cu?", "acceptedAnswer": { "@type": "Answer", "text": "Lowest listed price on BodyHackGuide: RU-58841 from $49.99, AHK-Cu from $44.99. 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