---
title: "LL-37 vs Thymosin Alpha-1 (TA1): Side-by-Side Comparison"
description: "Compare LL-37 vs Thymosin Alpha-1 (TA1) — mechanism, half-life, dose range, side effects, and live vendor pricing. LL-37 from $45.00. Thymosin Alpha-1 (TA1)"
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3.  LL-37 vs Thymosin Alpha-1 (TA1) 

# LL-37 vs  Thymosin Alpha-1 (TA1)

Side-by-side comparison of LL-37 and Thymosin Alpha-1 (TA1): mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land.

LL-37 from $45.00

Thymosin Alpha-1 (TA1) from $39.99

## Live price snapshot

### LL-37

Current low

$49.99

as of Sep 5, 2026

7-day low

$49.99

30-day low

$49.99

30-day change

— 

baseline building

### Thymosin Alpha-1 (TA1)

Current low

$49.99

as of Sep 5, 2026

7-day low

$49.99

30-day low

$49.99

30-day change

— 

baseline building

## LL-37

LL-37 is the only human cathelicidin, a 37-amino-acid amphipathic alpha-helical peptide (LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES) cleaved from the C-terminus of the 170-amino-acid precursor hCAP-18 (human cationic…

**Live lowest price:** $45.00 across 2 vendors

[Full LL-37 profile](/compound/ll-37)

## Thymosin Alpha-1 (TA1)

Thymosin alpha-1 (Tα1) is a 28-amino-acid N-acetylated peptide (N-Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn) isolated and characterized by Allan…

**Live lowest price:** $39.99 across 4 vendors

[Full Thymosin Alpha-1 (TA1) profile](/compound/thymosin-alpha-1)

## Side-by-side comparison

Attribute

LL-37

Thymosin Alpha-1 (TA1)

Category 

Immune & Inflammation

Immune & Inflammation

Research Stage 

Clinical

Approved (International)

Mechanism of Action 

LL-37's biological activity spans three functional categories: direct antimicrobial, immunomodulatory, and tissue-remodeling. Each operates through partially distinct mechanisms. Direct Antimicrobial Mechanism (Membrane Disruption): LL-37 is a cationic…

Thymosin alpha-1 does not act through a single canonical receptor in the way many peptides do. Its mechanism is pleiotropic, involving pattern-recognition receptors, modulation of immune cell maturation and function, and shifts in cytokine signaling patterns.…

Half-Life 

~30 minutes (free peptide; rapidly cleared by proteolysis). Human pharmacokinetics of exogenous LL-37 are not well characterized.

~2 hours

Typical Dose Range 

—

1,600 mcg (1.6 mg) per injection (standard clinical dose)

Dosing Frequency 

—

Twice weekly (subcutaneous) - the approved Zadaxin schedule; alternatively 900 mcg daily for intensive short-term courses

Administration 

—

Subcutaneous

Side Effects 

LL-37 has a less benign side-effect profile than many peptides covered in this guide, reflecting its mechanistic potency and narrow therapeutic window. Common (injection site): - Injection site irritation — more pronounced than with most peptides. Redness,…

Tα1 has one of the most benign side-effect profiles in the peptide space, supported by 45+ years of clinical experience in approved indications. Most users experience no acute side effects beyond mild injection site discomfort. Common (5-15% of users): -…

Molecular Weight 

4493.4 g/mol

3108 Da

Common Vial Sizes 

—

5mg, 10mg

## Price History

3 data points 

-   VANDL Labs 
-   Ion Peptide 
-   Disguised Alpha 

## Price History

4 data points 

-   OF 
-   VANDL Labs 
-   Ion Peptide 
-   Disguised Alpha 

### LL-37 — potential benefits

-   Broad-spectrum antimicrobial activity 
-   Wound healing acceleration 
-   Biofilm disruption 
-   Immune system modulation 
-   Anti-inflammatory effects 
-   Gut barrier support 

### Thymosin Alpha-1 (TA1) — potential benefits

-   Immune enhancement 
-   Antiviral defense 
-   Cancer adjuvant therapy 
-   Autoimmune modulation 
-   Vaccine potentiation 

## Frequently asked

### What's the difference between LL-37 and Thymosin Alpha-1 (TA1)?

LL-37 is a immune & inflammation that ll-37's biological activity spans three functional categories: direct antimicrobial, immunomodulatory, and tissue-remodeling. each operates through partially distinct mechanisms.…. Thymosin Alpha-1 (TA1) is a immune & inflammation that thymosin alpha-1 does not act through a single canonical receptor in the way many peptides do. its mechanism is pleiotropic, involving pattern-recognition receptors, modulation of…. The two differ in mechanism, half-life (~30 minutes (free peptide; rapidly cleared by proteolysis). Human pharmacokinetics of exogenous LL-37 are not well characterized. vs ~2 hours), and typical dose range.

### Which has the longer half-life, LL-37 or Thymosin Alpha-1 (TA1)?

LL-37 has a half-life of ~30 minutes (free peptide; rapidly cleared by proteolysis). Human pharmacokinetics of exogenous LL-37 are not well characterized.. Thymosin Alpha-1 (TA1) has a half-life of ~2 hours. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.

### Which is cheaper, LL-37 or Thymosin Alpha-1 (TA1)?

Current lowest live price on BodyHackGuide: LL-37 from $45.00, Thymosin Alpha-1 (TA1) from $39.99. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers.

### Can you stack LL-37 and Thymosin Alpha-1 (TA1)?

Stacking depends on mechanism overlap, safety profile, and goals. LL-37 and Thymosin Alpha-1 (TA1) should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.

## See current vendor prices

Live listings from the vendors we track, refreshed continuously.

[LL-37 prices](/compound/ll-37?tab=prices) [Thymosin Alpha-1 (TA1) prices](/compound/thymosin-alpha-1?tab=prices) [Compare all compounds](/compare)

### Before you buy LL-37 or Thymosin Alpha-1 (TA1)

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[View Vendor Scorecard](/vendors/scorecard)

## Related comparisons

[Thymosin-Alpha-1 vs BPC-157](/compare/thymosin-alpha-1-vs-bpc-157)[LL-37 vs BPC-157](/compare/ll-37-vs-bpc-157)[TB-500 vs Thymosin-Alpha-1](/compare/tb-500-vs-thymosin-alpha-1)[BPC-157 vs TB-500](/compare/bpc-157-vs-tb-500)[KPV vs BPC-157](/compare/kpv-vs-bpc-157)

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