--- title: "IGF-1 LR3 vs Ipamorelin: Side-by-Side Comparison (2026)" description: "Compare IGF-1 LR3 vs Ipamorelin — mechanism, half-life, dose range, side effects, and live vendor pricing. IGF-1 LR3 from $49.99. Ipamorelin from $24.99." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compare", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "IGF-1 LR3 vs Ipamorelin" } ] }, { "@context": "https://schema.org", "@type": "WebPage", "name": "IGF-1 LR3 vs Ipamorelin: Side-by-Side Comparison (2026)", "description": "Compare IGF-1 LR3 vs Ipamorelin — mechanism, half-life, dose range, side effects, and live vendor pricing. IGF-1 LR3 from $49.99. Ipamorelin from $24.99. 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Its five-amino-acid sequence (Aib-His-D-2Nal-D-Phe-Lys-NH₂) was discovered by Novo…", "url": "https://www.bodyhackguide.co/compound/ipamorelin", "category": "Growth Hormone / IGF-1 Axis", "offers": { "@type": "AggregateOffer", "lowPrice": "24.99", "priceCurrency": "USD", "offerCount": 5 } } } ] } }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. 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Ipamorelin is a growth hormone / igf-1 axis that ipamorelin acts as a selective agonist at the growth hormone secretagogue receptor 1a (ghs-r1a), the same receptor activated by endogenous ghrelin - the \"hunger hormone\" secreted…. The two differ in mechanism, half-life (20-30 hours (community/vendor estimate; no published human PK study of IGF-1 LR3) vs ~12 minutes for native IGF-1 vs ~2 hours (plasma)), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, IGF-1 LR3 or Ipamorelin?", "acceptedAnswer": { "@type": "Answer", "text": "IGF-1 LR3 has a half-life of 20-30 hours (community/vendor estimate; no published human PK study of IGF-1 LR3) vs ~12 minutes for native IGF-1. Ipamorelin has a half-life of ~2 hours (plasma). Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Which is cheaper, IGF-1 LR3 or Ipamorelin?", "acceptedAnswer": { "@type": "Answer", "text": "Current lowest live price on BodyHackGuide: IGF-1 LR3 from $49.99, Ipamorelin from $24.99. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers." } }, { "@type": "Question", "name": "Can you stack IGF-1 LR3 and Ipamorelin?", "acceptedAnswer": { "@type": "Answer", "text": "Stacking depends on mechanism overlap, safety profile, and goals. IGF-1 LR3 and Ipamorelin should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds." } } ] } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompare%2Figf-1-lr3-vs-ipamorelin) 100K+ researchers trust BodyHackGuide — Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 2. [Compare](/compare) 3. IGF-1 LR3 vs Ipamorelin # IGF-1 LR3 vs Ipamorelin Side-by-side comparison of IGF-1 LR3 and Ipamorelin: mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land. IGF-1 LR3 from $49.99 Ipamorelin from $24.99 ## Live price snapshot ### IGF-1 LR3 Current low $69.99 as of Sep 5, 2026 7-day low $69.99 30-day low $69.99 30-day change — baseline building ### Ipamorelin Current low $59.99 as of Sep 5, 2026 7-day low $59.99 30-day low $59.99 30-day change — baseline building ## IGF-1 LR3 IGF-1 LR3 (Long R3 IGF-1) is a synthetic analog of human insulin-like growth factor 1 modified at two positions to dramatically extend its serum half-life and amplify its tissue bioactivity compared to native IGF-1. The… **Live lowest price:** $49.99 across 5 vendors [Full IGF-1 LR3 profile](/compound/igf-1-lr3) ## Ipamorelin Ipamorelin is a selective pentapeptide ghrelin receptor (GHS-R1a) agonist — one of the most studied growth hormone secretagogues (GHS) in the biohacking community and the modern companion to CJC-1295 / MOD-GRF 1-29. Its… **Live lowest price:** $24.99 across 5 vendors [Full Ipamorelin profile](/compound/ipamorelin) ## Side-by-side comparison Attribute IGF-1 LR3 Ipamorelin Category Growth Hormone / IGF-1 Axis Growth Hormone / IGF-1 Axis Research Stage Preclinical Phase 2 Mechanism of Action IGF-1 Receptor Signaling IGF-1 LR3 binds the IGF-1 receptor (IGF1R) - a transmembrane receptor tyrosine kinase expressed on virtually every cell type in the human body. IGF1R activation triggers two principal intracellular signaling cascades: PI3K / Akt / mTOR… Ipamorelin acts as a selective agonist at the growth hormone secretagogue receptor 1a (GHS-R1a), the same receptor activated by endogenous ghrelin - the "hunger hormone" secreted primarily by P/D1 cells in the gastric fundus. The distinguishing feature of… Half-Life 20-30 hours (community/vendor estimate; no published human PK study of IGF-1 LR3) vs ~12 minutes for native IGF-1 ~2 hours (plasma) Typical Dose Range 20-80 mcg per day 100-300 mcg subcutaneous 1-3x daily (most commonly 200-300 mcg pre-bedtime); often combined with CJC-1295 without DAC at 100-300 mcg Dosing Frequency Once daily, typically post-workout or in the morning 1–3 times daily; most commonly once at bedtime Administration Subcutaneous, Intramuscular subcutaneous, intravenous (clinical only) Side Effects Acute and Common - Hypoglycemia — The primary acute safety concern. Post-injection blood glucose drops can produce shakiness, sweating, confusion, palpitations, and in severe cases loss of consciousness. Mitigation: 30-40g of fast-digesting carbohydrate within… Ipamorelin has the cleanest side-effect profile of any ghrelin-receptor agonist, which is why it dominates modern biohacking protocols. The profile is driven by (a) selective GHS-R1a agonism without cross-receptor activity, and (b) acute GH elevation (the same… Molecular Weight 9117 Da 711.9 Da Common Vial Sizes 100mcg, 1mg 2mg, 5mg ## Price History 6 data points - OF - Unknown - VANDL Labs - Unknown - Ion Peptide - Disguised Alpha ## Price History 4 data points - OF - VANDL Labs - Ion Peptide - Disguised Alpha ### IGF-1 LR3 — potential benefits - Muscle hypertrophy - Recovery - Protein synthesis - Fat metabolism - Glucose uptake ### Ipamorelin — potential benefits - Increased GH pulse amplitude (selective somatotroph activation) - Elevated IGF-1 (~30-80% over baseline) with consistent dosing - Improved slow-wave sleep architecture - No cortisol / prolactin / ACTH elevation (unique among GHS peptides) - Accelerated connective tissue and wound repair - Modest lean body mass gain + fat loss in hypogonadal adults - Enhanced recovery between training sessions - Synergistic effect with CJC-1295 / MOD-GRF 1-29 ## Frequently asked ### What's the difference between IGF-1 LR3 and Ipamorelin? IGF-1 LR3 is a growth hormone / igf-1 axis that igf-1 receptor signaling igf-1 lr3 binds the igf-1 receptor (igf1r) - a transmembrane receptor tyrosine kinase expressed on virtually every cell type in the human body. igf1r…. Ipamorelin is a growth hormone / igf-1 axis that ipamorelin acts as a selective agonist at the growth hormone secretagogue receptor 1a (ghs-r1a), the same receptor activated by endogenous ghrelin - the "hunger hormone" secreted…. The two differ in mechanism, half-life (20-30 hours (community/vendor estimate; no published human PK study of IGF-1 LR3) vs ~12 minutes for native IGF-1 vs ~2 hours (plasma)), and typical dose range. ### Which has the longer half-life, IGF-1 LR3 or Ipamorelin? IGF-1 LR3 has a half-life of 20-30 hours (community/vendor estimate; no published human PK study of IGF-1 LR3) vs ~12 minutes for native IGF-1. Ipamorelin has a half-life of ~2 hours (plasma). Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, IGF-1 LR3 or Ipamorelin? Current lowest live price on BodyHackGuide: IGF-1 LR3 from $49.99, Ipamorelin from $24.99. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers. ### Can you stack IGF-1 LR3 and Ipamorelin? Stacking depends on mechanism overlap, safety profile, and goals. IGF-1 LR3 and Ipamorelin should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Live listings from the vendors we track, refreshed continuously. [IGF-1 LR3 prices](/compound/igf-1-lr3?tab=prices) [Ipamorelin prices](/compound/ipamorelin?tab=prices) [Compare all compounds](/compare) ### Before you buy IGF-1 LR3 or Ipamorelin Check the vendor trust score. Every supplier we track is rated 0–100 on COA verification, payment transparency, shipping, reviews, and listings — one published, reproducible methodology, applied to every vendor including BHG Labs, which shares our ownership. [View Vendor Scorecard](/vendors/scorecard) ## Related comparisons [Ipamorelin vs MK-677](/compare/ipamorelin-vs-mk-677)[CJC-1295 vs Ipamorelin](/compare/cjc-1295-vs-ipamorelin)[Sermorelin vs Ipamorelin](/compare/sermorelin-vs-ipamorelin)[Hexarelin vs Ipamorelin](/compare/hexarelin-vs-ipamorelin)[GHRP-2 vs Ipamorelin](/compare/ghrp-2-vs-ipamorelin)[Tesamorelin vs CJC-1295](/compare/tesamorelin-vs-cjc-1295)[GHRP-2 vs GHRP-6](/compare/ghrp-2-vs-ghrp-6)[Tesamorelin vs Sermorelin](/compare/tesamorelin-vs-sermorelin) **Research use only.** BodyHackGuide is a research and price-comparison reference. BodyHackGuide and BHG Labs share common ownership. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. 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