--- title: "Humanin vs Cartalax: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/humanin-vs-cartalax description: "Compare Humanin vs Cartalax side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # Humanin vs Cartalax Side-by-side comparison of Humanin and Cartalax: mechanism, half-life, dose range, safety profile, and vendor pricing. Humanin from $85.60 Cartalax from $49.99 ## Price snapshot ### Humanin Current low $85.60 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### Cartalax Current low $49.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## Humanin Humanin is a 24-amino-acid peptide (MAPRGFSCLLLLTSEIDLPVKRRA) encoded within the mitochondrial 16S ribosomal RNA gene and translated from a short open reading frame that was not recognized as biologically active until… **Lowest listed price:** $85.60 across 2 listings Full Humanin profile (https://www.bodyhackguide.co/compound/humanin) ## Cartalax Cartalax is a short synthetic peptide developed in Russia by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology, positioned as a "cartilage bioregulator" intended to… **Lowest listed price:** $49.99 across 3 listings Full Cartalax profile (https://www.bodyhackguide.co/compound/cartalax) ## Side-by-side comparison | Attribute | Humanin | Cartalax | | --- | --- | --- | | Category | Recovery | Recovery | | Research Stage | Preclinical | Preclinical | | Mechanism of Action | Humanin signals through a heterotrimeric cell-surface receptor complex consisting of ciliary neurotrophic factor receptor alpha (CNTFR-alpha), WSX-1 (also known as IL-27R-alpha), and glycoprotein 130 (gp130) ([Ying et al., 2004]; [Hashimoto et al., 2009]).… | Mechanism of Action Cartalax's proposed mechanism is the Khavinson short-peptide framework applied to cartilage: passive membrane permeation, nuclear import, and sequence-selective chromatin modulation producing chondrocyte-favourable transcriptional shifts.… | | Half-Life | Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist. | No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured. | | Typical Dose Range | Research compound — no established human doses | 20 mg oral/sublingual once daily for 10 days; 60-90 day washout | | Dosing Frequency | Once daily subcutaneous in anecdotal use (some split twice daily for the short half-life); no validated human regimen | Once daily | | Administration | — | — | | Side Effects | The side effect profile of humanin in humans is not established because no properly designed clinical trials have been published. The preclinical safety profile in rodents is reassuring: across numerous studies using wild-type humanin and HNG at doses… | Side Effects and Safety Cartalax has been used in Russian clinical settings for roughly 20 years with a sparse adverse-event literature — reassuring in direction, insufficient for confident pharmacovigilance. Reported short-term adverse effects -… | | Molecular Weight | 2687.26 Da | 446.5 Da (C18H30N4O9) | | Common Vial Sizes | — | — | ## Price History 2 data points - Disguised Alpha - LB ## Price History 3 data points - Ion Peptide - Disguised Alpha - LB ### Humanin: potential benefits - Cytoprotective effects - Anti-apoptotic properties - Neuroprotective potential - Cardioprotective effects - Cellular stress resistance ### Cartalax: potential benefits - Joint and cartilage repair support - Connective tissue maintenance - Anti-aging effects on musculoskeletal system - Improved joint mobility ## Frequently asked ### What's the difference between Humanin and Cartalax? Humanin is a recovery that humanin signals through a heterotrimeric cell-surface receptor complex consisting of ciliary neurotrophic factor receptor alpha (cntfr-alpha), wsx-1 (also known as il-27r-alpha),…. Cartalax is a recovery that mechanism of action cartalax's proposed mechanism is the khavinson short-peptide framework applied to cartilage: passive membrane permeation, nuclear import, and sequence-selective…. The two differ in mechanism, half-life (Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist. vs No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured.), and typical dose range. ### Which has the longer half-life, Humanin or Cartalax? Humanin has a half-life of Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist.. Cartalax has a half-life of No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, Humanin or Cartalax? Lowest listed price on BodyHackGuide: Humanin from $85.60, Cartalax from $49.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack Humanin and Cartalax? Stacking depends on mechanism overlap, safety profile, and goals. Humanin and Cartalax should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. Humanin prices: https://www.bodyhackguide.co/compound/humanin?tab=prices Cartalax prices: https://www.bodyhackguide.co/compound/cartalax?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy Humanin or Cartalax Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. 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Cartalax is a recovery that mechanism of action cartalax's proposed mechanism is the khavinson short-peptide framework applied to cartilage: passive membrane permeation, nuclear import, and sequence-selective…. The two differ in mechanism, half-life (Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist. vs No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured.), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, Humanin or Cartalax?", "acceptedAnswer": { "@type": "Answer", "text": "Humanin has a half-life of Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist.. Cartalax has a half-life of No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Which is cheaper, Humanin or Cartalax?", "acceptedAnswer": { "@type": "Answer", "text": "Lowest listed price on BodyHackGuide: Humanin from $85.60, Cartalax from $49.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers." } }, { "@type": "Question", "name": "Can you stack Humanin and Cartalax?", "acceptedAnswer": { "@type": "Answer", "text": "Stacking depends on mechanism overlap, safety profile, and goals. Humanin and Cartalax should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds." } } ] } ] ```