--- title: "HGH Fragment 176-191 vs Tesofensine: Compared (2026)" url: https://www.bodyhackguide.co/compare/hgh-frag-176-191-vs-tesofensine description: "Compare HGH Fragment 176-191 vs Tesofensine side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # HGH Fragment 176-191 vs Tesofensine Side-by-side comparison of HGH Fragment 176-191 and Tesofensine: mechanism, half-life, dose range, safety profile, and vendor pricing. HGH Fragment 176-191 from $49.99 Tesofensine from $79.99 ## Price snapshot ### HGH Fragment 176-191 Current low $49.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### Tesofensine Current low $79.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## HGH Fragment 176-191 HGH Fragment 176-191 (also written HGH Frag 176-191, hGH Fragment 176-191, and frequently appearing in clinical literature as AOD-9604 — "Anti-Obesity Drug 9604") is a synthetic peptide corresponding to the C-terminal… **Lowest listed price:** $49.99 across 1 listing Full HGH Fragment 176-191 profile (https://www.bodyhackguide.co/compound/hgh-frag-176-191) ## Tesofensine Tesofensine (NS2330) is an orally-administered small-molecule triple monoamine reuptake inhibitor — it blocks the reuptake of noradrenaline, dopamine, and serotonin, placing it in the same broad pharmacologic class as… **Lowest listed price:** $79.99 across 2 listings Full Tesofensine profile (https://www.bodyhackguide.co/compound/tesofensine) ## Side-by-side comparison | Attribute | HGH Fragment 176-191 | Tesofensine | | --- | --- | --- | | Category | Metabolic & Weight Loss | Weight Loss | | Research Stage | Phase 2 (discontinued) | Preclinical | | Mechanism of Action | HGH Fragment 176-191's proposed mechanism of action is grounded in the structural dissection of the native human growth hormone molecule. Full-length hGH (residues 1-191) is a 22 kDa peptide that binds two distinct functional domains to the growth hormone… | Tesofensine blocks the presynaptic reuptake of three monoamine neurotransmitters: noradrenaline (norepinephrine), dopamine, and serotonin. By inhibiting the neurotransmitter transporters (NET, DAT, and SERT respectively), tesofensine raises synaptic… | | Half-Life | ~30 minutes (short plasma half-life) | — | | Typical Dose Range | 250-500 mcg | 0.25 mg - 1 mg daily (oral) | | Dosing Frequency | Once or twice daily, fasted | — | | Administration | — | — | | Side Effects | HGH Fragment 176-191 / AOD-9604 has been reported as well tolerated in Phase 1 and Phase 2 trials, with side effects that were mostly mild and self-limiting. However, "well tolerated in a Phase 2 trial that failed its primary endpoint" is a different safety… | Tesofensine's side effect profile reflects its monoamine-enhancing mechanism. Most effects are predictable extensions of NE, DA, and 5-HT elevation. The cardiovascular profile is the dominant clinical concern and the primary reason regulators have not approved… | | Molecular Weight | 1815.1 g/mol | 298.24 g/mol | | Common Vial Sizes | — | — | ## Price tracking Tracking HGH Fragment 176-191 prices since September 5, 2026. Trend chart unlocks once we have price snapshots from more than one day. ## Price tracking Tracking Tesofensine prices since July 1, 2026. Trend chart unlocks once we have price snapshots from more than one day. ### HGH Fragment 176-191: potential benefits - Targeted fat loss - Visceral fat reduction - No insulin resistance - Metabolic improvement - No IGF-1 elevation ### Tesofensine: potential benefits - Significant weight loss (10-15% body weight) - Appetite suppression - Increased metabolic rate - Enhanced dopamine-driven motivation ## Frequently asked ### What's the difference between HGH Fragment 176-191 and Tesofensine? HGH Fragment 176-191 is a metabolic & weight loss that hgh fragment 176-191's proposed mechanism of action is grounded in the structural dissection of the native human growth hormone molecule. full-length hgh (residues 1-191) is a 22…. Tesofensine is a weight loss that tesofensine blocks the presynaptic reuptake of three monoamine neurotransmitters: noradrenaline (norepinephrine), dopamine, and serotonin. by inhibiting the neurotransmitter…. The two differ in mechanism, half-life (~30 minutes (short plasma half-life) vs not reported), and typical dose range. ### Which has the longer half-life, HGH Fragment 176-191 or Tesofensine? HGH Fragment 176-191 has a half-life of ~30 minutes (short plasma half-life). Tesofensine has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, HGH Fragment 176-191 or Tesofensine? Lowest listed price on BodyHackGuide: HGH Fragment 176-191 from $49.99, Tesofensine from $79.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack HGH Fragment 176-191 and Tesofensine? Stacking depends on mechanism overlap, safety profile, and goals. HGH Fragment 176-191 and Tesofensine should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. HGH Fragment 176-191 prices: https://www.bodyhackguide.co/compound/hgh-frag-176-191?tab=prices Tesofensine prices: https://www.bodyhackguide.co/compound/tesofensine?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy HGH Fragment 176-191 or Tesofensine Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). BodyHackGuide (https://www.bodyhackguide.co/) Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology). Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. 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Tesofensine is a weight loss that tesofensine blocks the presynaptic reuptake of three monoamine neurotransmitters: noradrenaline (norepinephrine), dopamine, and serotonin. by inhibiting the neurotransmitter…. The two differ in mechanism, half-life (~30 minutes (short plasma half-life) vs not reported), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, HGH Fragment 176-191 or Tesofensine?", "acceptedAnswer": { "@type": "Answer", "text": "HGH Fragment 176-191 has a half-life of ~30 minutes (short plasma half-life). Tesofensine has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Which is cheaper, HGH Fragment 176-191 or Tesofensine?", "acceptedAnswer": { "@type": "Answer", "text": "Lowest listed price on BodyHackGuide: HGH Fragment 176-191 from $49.99, Tesofensine from $79.99. 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