--- title: "DSIP vs Cortagen: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/dsip-vs-cortagen description: "Compare DSIP vs Cortagen side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices. DSIP from $34.99." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # DSIP (Delta Sleep-Inducing Peptide) vs Cortagen Side-by-side comparison of DSIP (Delta Sleep-Inducing Peptide) and Cortagen: mechanism, half-life, dose range, safety profile, and vendor pricing. DSIP (Delta Sleep-Inducing Peptide) from $34.99 Cortagen from $79.00 ## Price snapshot ### DSIP (Delta Sleep-Inducing Peptide) Current low $34.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### Cortagen Current low $79.00 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## DSIP (Delta Sleep-Inducing Peptide) Delta sleep-inducing peptide (DSIP) is a nonapeptide — a 9-amino-acid neuropeptide with sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE, 848 Da molecular weight) — first isolated in 1977 from the cerebral venous… **Lowest listed price:** $34.99 across 11 listings Full DSIP (Delta Sleep-Inducing Peptide) profile (https://www.bodyhackguide.co/compound/dsip) ## Cortagen Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) from the Khavinson bioregulator family developed at the St. Petersburg Institute of Bioregulation and Gerontology. It is organ-targeted to cardiac and coronary… **Lowest listed price:** $79.00 across 1 listing Full Cortagen profile (https://www.bodyhackguide.co/compound/cortagen) ## Side-by-side comparison | Attribute | DSIP (Delta Sleep-Inducing Peptide) | Cortagen | | --- | --- | --- | | Category | Cognition, Mood & Neuroprotection | Longevity | | Research Stage | Research Use Only | Preclinical | | Mechanism of Action | Primary Mechanism: Uncharacterized Direct Receptor Binding After more than four decades of research, DSIP's primary molecular target remains unknown. No specific receptor has been cloned, characterized, or reproducibly identified as the primary binding site… | Cortagen is a synthetic tetrapeptide, Ala-Glu-Asp-Pro (AEDP), created by the Khavinson group through directed synthesis based on the amino-acid composition of Cortexin, a polypeptide complex extracted from the cerebral cortex [PMID:15159690]. It is a… | | Half-Life | ~7-15 minutes (IV; plasma clearance is rapid, though subjective sleep effects can outlast measurable blood levels) | Unknown (tetrapeptide; estimated <4 hours) | | Typical Dose Range | 100–300 mcg per injection | — | | Dosing Frequency | Once daily, 30–60 minutes before bedtime | once_daily | | Administration | Subcutaneous, Intramuscular, Intranasal | Subcutaneous, Intramuscular | | Side Effects | Overall Safety Profile DSIP has one of the cleanest safety profiles of any peptide in the research chemical space. In 40+ years of research and clinical use, no serious adverse events have been reported in controlled trials or large case series. The compound… | — | | Molecular Weight | 848.8 Da | 430.4 g/mol (C17H26N4O9, PubChem CID 18439621) | | Common Vial Sizes | 2mg, 5mg | 20 | ## Price History 8 data points - BM - Half Nattys - LB - Ion Peptide - OF - Disguised Alpha - BHG Labs ## Price tracking Tracking Cortagen prices since April 22, 2026. Trend chart unlocks once we have price snapshots from more than one day. ### DSIP (Delta Sleep-Inducing Peptide): potential benefits - Sleep quality support - Stress reduction - Cortisol/HPA modulation - Alcohol & opioid withdrawal support - Circadian regulation ### Cortagen: potential benefits - Peripheral nerve repair - accelerated axon regeneration and faster nerve-conduction recovery after injury in rat models [PMID:11276314; PMID:12134478] - Neuroprotection and antioxidant activity in the cerebral cortex and in chronic brain-ischemia models (preclinical) [PMID:18239817; PMID:21476278] - CNS/cognitive support as the synthetic short-peptide analog of the cortex-derived Russian drug Cortexin - Anti-aging chromatin remodeling - reactivation of age-silenced ribosomal genes in lymphocytes from elderly donors [PMID:15085253; PMID:37042594] - Mild immune-signaling modulation (IL-2 expression), generally weaker than Vilon or Epithalon [PMID:12447482; PMID:16224591] - Longevity-protocol stacking as one of the Khavinson short-peptide bioregulators (commonly paired with Epitalon or Pinealon) ## Frequently asked ### What's the difference between DSIP (Delta Sleep-Inducing Peptide) and Cortagen? DSIP (Delta Sleep-Inducing Peptide) is a cognition, mood & neuroprotection that primary mechanism: uncharacterized direct receptor binding after more than four decades of research, dsip's primary molecular target remains unknown. no specific receptor has been…. Cortagen is a longevity that cortagen is a synthetic tetrapeptide, ala-glu-asp-pro (aedp), created by the khavinson group through directed synthesis based on the amino-acid composition of cortexin, a…. The two differ in mechanism, half-life (~7-15 minutes (IV; plasma clearance is rapid, though subjective sleep effects can outlast measurable blood levels) vs Unknown (tetrapeptide; estimated <4 hours)), and typical dose range. ### Which has the longer half-life, DSIP (Delta Sleep-Inducing Peptide) or Cortagen? DSIP (Delta Sleep-Inducing Peptide) has a half-life of ~7-15 minutes (IV; plasma clearance is rapid, though subjective sleep effects can outlast measurable blood levels). Cortagen has a half-life of Unknown (tetrapeptide; estimated <4 hours). Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, DSIP (Delta Sleep-Inducing Peptide) or Cortagen? Lowest listed price on BodyHackGuide: DSIP (Delta Sleep-Inducing Peptide) from $34.99, Cortagen from $79.00. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers. ### Can you stack DSIP (Delta Sleep-Inducing Peptide) and Cortagen? Stacking depends on mechanism overlap, safety profile, and goals. DSIP (Delta Sleep-Inducing Peptide) and Cortagen should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. DSIP (Delta Sleep-Inducing Peptide) prices: https://www.bodyhackguide.co/compound/dsip?tab=prices Cortagen prices: https://www.bodyhackguide.co/compound/cortagen?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy DSIP (Delta Sleep-Inducing Peptide) or Cortagen Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons DSIP vs Melatonin: https://www.bodyhackguide.co/compare/dsip-vs-melatonin **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. 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