--- title: "DMHA vs MOTS-c: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/dmha-vs-mots-c description: "Compare DMHA vs MOTS-c side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices. MOTS-c from $44.99." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # DMHA vs MOTS-c Side-by-side comparison of DMHA and MOTS-c: mechanism, half-life, dose range, safety profile, and vendor pricing. DMHA: no price on file MOTS-c from $44.99 ## Price snapshot ### DMHA Current low — 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### MOTS-c Current low $44.99 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## DMHA DMHA (octodrine) - chemically 2-amino-6-methylheptane, also sold as 2-aminoisoheptane or 1,5-dimethylhexylamine - is an aliphatic-amine central nervous system stimulant and a close structural analog of DMAA… No vendor price on file. Full DMHA profile (https://www.bodyhackguide.co/compound/dmha) ## MOTS-c MOTS-c (Mitochondrial ORF of the Twelve S rRNA type-c) is a 16-amino-acid mitochondrial-derived peptide — a member of a recently discovered class of small peptides encoded in mitochondrial DNA rather than nuclear DNA. It… **Lowest listed price:** $44.99 across 9 listings Full MOTS-c profile (https://www.bodyhackguide.co/compound/mots-c) ## Side-by-side comparison | Attribute | DMHA | MOTS-c | | --- | --- | --- | | Category | Energy & Performance | Longevity & Cellular Health | | Research Stage | Historical pharmaceutical; no modern clinical trials | Preclinical | | Mechanism of Action | DMHA (octodrine; 2-amino-6-methylheptane / 1,5-dimethylhexylamine) is a simple aliphatic amine that behaves as an indirect sympathomimetic - structurally and pharmacologically a close cousin of DMAA (1,3-dimethylamylamine). Agents in this class raise synaptic… | A New Class of Signaling Molecule MOTS-c belongs to the mitochondrial-derived peptides (MDPs) - a class of small peptides encoded within mitochondrial DNA open reading frames that were historically thought to encode only ribosomal RNAs. The known MDPs include:… | | Half-Life | Not formally characterized in humans. After ingestion, octodrine is rapidly metabolized to heptaminol, which becomes the predominant compound detected in blood and urine within hours [PMID:39401652]. Users commonly report perceptible stimulant effects lasting roughly 3-6 hours, but this is anecdotal rather than measured pharmacokinetics. | ~4–6 hours | | Typical Dose Range | 75-200 mg per dose (anecdotal pre-workout range; ~75,000-200,000 mcg). Historical pharmaceutical unit dose was 8-33 mg. No approved or clinically validated dose exists. | 5,000–10,000 mcg (5–10 mg) per injection | | Dosing Frequency | Acute, single-session (pre-workout) use rather than a daily or continuous compound. Users typically leave rest days between doses to limit tolerance buildup and cardiovascular strain; there is no evidence base for any regular dosing schedule. | 2-3 times per week | | Administration | — | Subcutaneous, Intramuscular | | Side Effects | Reported and expected effects reflect its sympathomimetic activity: elevated blood pressure and heart rate, palpitations or tachycardia, chest tightness, shortness of breath (dyspnoea), overheating (hyperthermia), anxiety and jitteriness, headache, insomnia,… | Reported Effects (limited human data) - Injection site reactions — Mild erythema, transient itching at SC injection site. Site rotation minimizes. Probably the single most reported issue. - Transient fatigue — Some users report mild fatigue in the first week… | | Molecular Weight | 129.24 g/mol (free base; molecular formula C8H19N). Commonly supplied as a salt (e.g., hydrochloride or, historically, camphorsulfonate), which increases the labeled mass per dose. | 2174 Da | | Common Vial Sizes | — | 5mg, 10mg | ## Price History 5 data points - OF - BM - Half Nattys - Ion Peptide - Disguised Alpha - BHG Labs ### DMHA: potential benefits - Increased energy and perceived training intensity - the reason it is added to pre-workout products (reported by users; not established in any controlled trial) - Sharper focus and heightened alertness from central nervous system stimulation - Appetite suppression, which is why it appears in 'fat-burner' formulas - Mild mood lift or euphoria reported anecdotally - Users often describe a longer, 'smoother' stimulant feel than caffeine alone - again anecdotal, not clinically demonstrated ### MOTS-c: potential benefits - Insulin sensitivity - Exercise mimicry - Metabolic health - Anti-aging - Fat oxidation - Longevity ## Frequently asked ### What's the difference between DMHA and MOTS-c? DMHA is a energy & performance that dmha (octodrine; 2-amino-6-methylheptane / 1,5-dimethylhexylamine) is a simple aliphatic amine that behaves as an indirect sympathomimetic - structurally and pharmacologically a…. MOTS-c is a longevity & cellular health that a new class of signaling molecule mots-c belongs to the mitochondrial-derived peptides (mdps) - a class of small peptides encoded within mitochondrial dna open reading frames that…. The two differ in mechanism, half-life (Not formally characterized in humans. After ingestion, octodrine is rapidly metabolized to heptaminol, which becomes the predominant compound detected in blood and urine within hours [PMID:39401652]. Users commonly report perceptible stimulant effects lasting roughly 3-6 hours, but this is anecdotal rather than measured pharmacokinetics. vs ~4–6 hours), and typical dose range. ### Which has the longer half-life, DMHA or MOTS-c? DMHA has a half-life of Not formally characterized in humans. After ingestion, octodrine is rapidly metabolized to heptaminol, which becomes the predominant compound detected in blood and urine within hours [PMID:39401652]. Users commonly report perceptible stimulant effects lasting roughly 3-6 hours, but this is anecdotal rather than measured pharmacokinetics.. MOTS-c has a half-life of ~4–6 hours. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Can you stack DMHA and MOTS-c? Stacking depends on mechanism overlap, safety profile, and goals. DMHA and MOTS-c should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. DMHA prices: https://www.bodyhackguide.co/compound/dmha?tab=prices MOTS-c prices: https://www.bodyhackguide.co/compound/mots-c?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy DMHA or MOTS-c Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons MOTS C vs SS-31: https://www.bodyhackguide.co/compare/mots-c-vs-ss-31 Methylene Blue vs MOTS C: https://www.bodyhackguide.co/compare/methylene-blue-vs-mots-c MOTS C vs NMN: https://www.bodyhackguide.co/compare/mots-c-vs-nmn **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. 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