---
title: "Cortagen vs Glutathione: Side-by-Side Comparison (2026)"
url: https://www.bodyhackguide.co/compare/cortagen-vs-glutathione
description: "Compare Cortagen vs Glutathione side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices."
lang: en
---

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# Cortagen vs Glutathione

Side-by-side comparison of Cortagen and Glutathione: mechanism, half-life, dose range, safety profile, and vendor pricing.

Cortagen from $79.00

Glutathione from $29.00

## Price snapshot

### Cortagen

Current low

$79.00

current listings

7-day low

—

not enough history yet

30-day low

—

not enough history yet

30-day change

—

not enough history yet

### Glutathione

Current low

$29.00

current listings

7-day low

—

not enough history yet

30-day low

—

not enough history yet

30-day change

—

not enough history yet

## Cortagen

Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) from the Khavinson bioregulator family developed at the St. Petersburg Institute of Bioregulation and Gerontology. It is organ-targeted to cardiac and coronary…

**Lowest listed price:** $79.00 across 1 listing

Full Cortagen profile (https://www.bodyhackguide.co/compound/cortagen)

## Glutathione

Glutathione is the body's most abundant intracellular antioxidant — a three-amino-acid peptide made of glutamate, cysteine, and glycine (Glu-Cys-Gly), present in millimolar concentrations inside every cell of your body.…

**Lowest listed price:** $29.00 across 8 listings

Full Glutathione profile (https://www.bodyhackguide.co/compound/glutathione)

## Side-by-side comparison

| Attribute | Cortagen | Glutathione |
| --- | --- | --- |
| Category | Longevity | Recovery |
| Research Stage | Preclinical | Clinical |
| Mechanism of Action | Cortagen is a synthetic tetrapeptide, Ala-Glu-Asp-Pro (AEDP), created by the Khavinson group through directed synthesis based on the amino-acid composition of Cortexin, a polypeptide complex extracted from the cerebral cortex [PMID:15159690]. It is a… | Glutathione's mechanisms extend far beyond the simple "antioxidant" label that dominates popular marketing. Understanding these mechanisms matters because they determine where supplementation is likely to help and where it is unlikely to make any difference.… |
| Half-Life | Unknown (tetrapeptide; estimated <4 hours) | Short: on the order of minutes for intravenous glutathione (intact GSH is cleared rapidly from plasma and cellular uptake of intact GSH is limited). Oral bioavailability is low, so tissue glutathione levels depend mainly on endogenous synthesis from cysteine, glycine, and glutamate rather than on the half-life of administered GSH. |
| Typical Dose Range | — | 250 mg - 1000 mg daily (oral, IV, or nebulized) |
| Dosing Frequency | once_daily | — |
| Administration | Subcutaneous, Intramuscular | — |
| Side Effects | — | Glutathione has an excellent overall safety profile at typical supplement and medical doses. Serious adverse events are rare, and most side effects are mild and self-limited. That said, "safe" is not "sideeffect-free," and specific formulations and routes… |
| Molecular Weight | 430.4 g/mol (C17H26N4O9, PubChem CID 18439621) | 307.32 g/mol (C10H17N3O6S) |
| Common Vial Sizes | 20 | — |

## Price tracking

Tracking Cortagen prices since April 22, 2026. Trend chart unlocks once we have price snapshots from more than one day.

## Price History

4 data points

- Half Nattys
- Ion Peptide
- BHG Labs

### Cortagen: potential benefits

- Peripheral nerve repair - accelerated axon regeneration and faster nerve-conduction recovery after injury in rat models [PMID:11276314; PMID:12134478]
- Neuroprotection and antioxidant activity in the cerebral cortex and in chronic brain-ischemia models (preclinical) [PMID:18239817; PMID:21476278]
- CNS/cognitive support as the synthetic short-peptide analog of the cortex-derived Russian drug Cortexin
- Anti-aging chromatin remodeling - reactivation of age-silenced ribosomal genes in lymphocytes from elderly donors [PMID:15085253; PMID:37042594]
- Mild immune-signaling modulation (IL-2 expression), generally weaker than Vilon or Epithalon [PMID:12447482; PMID:16224591]
- Longevity-protocol stacking as one of the Khavinson short-peptide bioregulators (commonly paired with Epitalon or Pinealon)

### Glutathione: potential benefits

- Powerful antioxidant protection
- Liver detoxification support
- Immune system enhancement
- Skin brightening and anti-aging
- Heavy metal chelation support
- Reduced oxidative stress

## Frequently asked

### What's the difference between Cortagen and Glutathione?

Cortagen is a longevity that cortagen is a synthetic tetrapeptide, ala-glu-asp-pro (aedp), created by the khavinson group through directed synthesis based on the amino-acid composition of cortexin, a…. Glutathione is a recovery that glutathione's mechanisms extend far beyond the simple "antioxidant" label that dominates popular marketing. understanding these mechanisms matters because they determine where…. The two differ in mechanism, half-life (Unknown (tetrapeptide; estimated <4 hours) vs Short: on the order of minutes for intravenous glutathione (intact GSH is cleared rapidly from plasma and cellular uptake of intact GSH is limited). Oral bioavailability is low, so tissue glutathione levels depend mainly on endogenous synthesis from cysteine, glycine, and glutamate rather than on the half-life of administered GSH.), and typical dose range.

### Which has the longer half-life, Cortagen or Glutathione?

Cortagen has a half-life of Unknown (tetrapeptide; estimated <4 hours). Glutathione has a half-life of Short: on the order of minutes for intravenous glutathione (intact GSH is cleared rapidly from plasma and cellular uptake of intact GSH is limited). Oral bioavailability is low, so tissue glutathione levels depend mainly on endogenous synthesis from cysteine, glycine, and glutamate rather than on the half-life of administered GSH.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.

### Which is cheaper, Cortagen or Glutathione?

Lowest listed price on BodyHackGuide: Cortagen from $79.00, Glutathione from $29.00. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.

### Can you stack Cortagen and Glutathione?

Stacking depends on mechanism overlap, safety profile, and goals. Cortagen and Glutathione should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.

## See current vendor prices

Listings from the vendors we track. Prices change often, so check the vendor before you buy.

Cortagen prices: https://www.bodyhackguide.co/compound/cortagen?tab=prices

Glutathione prices: https://www.bodyhackguide.co/compound/glutathione?tab=prices

Compare all compounds: https://www.bodyhackguide.co/compare

### Before you buy Cortagen or Glutathione

Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor.

View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard)

## Related comparisons

NAC vs Glutathione: https://www.bodyhackguide.co/compare/nac-vs-glutathione
Alpha Lipoic Acid vs Glutathione: https://www.bodyhackguide.co/compare/alpha-lipoic-acid-vs-glutathione

**Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks, and every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure).

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