--- title: "CJC-1295 (Mod GRF 1-29) vs Sermorelin: Side-by-Side" description: "Compare CJC-1295 (Mod GRF 1-29) vs Sermorelin — mechanism, half-life, dose range, side effects, and live vendor pricing. CJC-1295 (Mod GRF 1-29) from $29.00." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compare", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "CJC-1295 (Mod GRF 1-29) vs Sermorelin" } ] }, { "@context": "https://schema.org", "@type": "WebPage", "name": "CJC-1295 (Mod GRF 1-29) vs Sermorelin: Side-by-Side Comparison (2026)", "description": "Compare CJC-1295 (Mod GRF 1-29) vs Sermorelin — mechanism, half-life, dose range, side effects, and live vendor pricing. CJC-1295 (Mod GRF 1-29) from $29.00. Sermorelin from $24.99. 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Sermorelin is a growth hormone / igf-1 axis that ghrh receptor pharmacology sermorelin is a truncated analog - the first 29 amino acids - of the 44-amino-acid native ghrh produced by the arcuate nucleus of the hypothalamus. the…. The two differ in mechanism, half-life (~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding) vs ~10-20 minutes (plasma; native GHRH 7 minutes)), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, CJC-1295 (Mod GRF 1-29) or Sermorelin?", "acceptedAnswer": { "@type": "Answer", "text": "CJC-1295 (Mod GRF 1-29) has a half-life of ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding). Sermorelin has a half-life of ~10-20 minutes (plasma; native GHRH 7 minutes). Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Which is cheaper, CJC-1295 (Mod GRF 1-29) or Sermorelin?", "acceptedAnswer": { "@type": "Answer", "text": "Current lowest live price on BodyHackGuide: CJC-1295 (Mod GRF 1-29) from $29.00, Sermorelin from $24.99. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers." } }, { "@type": "Question", "name": "Can you stack CJC-1295 (Mod GRF 1-29) and Sermorelin?", "acceptedAnswer": { "@type": "Answer", "text": "Stacking depends on mechanism overlap, safety profile, and goals. CJC-1295 (Mod GRF 1-29) and Sermorelin should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds." } } ] } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompare%2Fcjc-1295-vs-sermorelin) 100K+ researchers trust BodyHackGuide — Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 2. [Compare](/compare) 3. CJC-1295 (Mod GRF 1-29) vs Sermorelin # CJC-1295 (Mod GRF 1-29) vs Sermorelin Side-by-side comparison of CJC-1295 (Mod GRF 1-29) and Sermorelin: mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land. CJC-1295 (Mod GRF 1-29) from $29.00 Sermorelin from $24.99 ## Live price snapshot ### CJC-1295 (Mod GRF 1-29) Current low $49.00 as of Apr 22, 2026 7-day low — no 7d data yet 30-day low — no 30d data yet 30-day change — baseline building ### Sermorelin Current low $49.99 as of Sep 5, 2026 7-day low $49.99 30-day low $49.99 30-day change — baseline building ## CJC-1295 (Mod GRF 1-29) Featured CJC-1295 without DAC (also called Modified GRF 1-29 or MOD-GRF 1-29) is a 30-amino-acid analog of the first 29 residues of endogenous Growth Hormone Releasing Hormone (GHRH), with four strategic substitutions (D-Ala² for… **Live lowest price:** $29.00 across 6 vendors [Full CJC-1295 (Mod GRF 1-29) profile](/compound/cjc-1295) ## Sermorelin Sermorelin acetate is a synthetic 29-amino-acid peptide corresponding to the biologically active N-terminal fragment of human growth hormone-releasing hormone (GHRH 1-29). It was one of the first GHRH analogs to achieve… **Live lowest price:** $24.99 across 8 vendors [Full Sermorelin profile](/compound/sermorelin) ## Side-by-side comparison Attribute CJC-1295 (Mod GRF 1-29) Sermorelin Category Growth Hormone / IGF-1 Axis Growth Hormone / IGF-1 Axis Research Stage Phase 2 (clinical development discontinued) FDA-Approved (Geref, discontinued 2008) Mechanism of Action MOD-GRF 1-29 exerts its effect through a single, well-characterized receptor: the GHRH receptor (GHRHR) on anterior-pituitary somatotroph cells. The signaling cascade is the same as endogenous GHRH; the difference is pharmacokinetics. 1. GHRH receptor agonism… GHRH Receptor Pharmacology Sermorelin is a truncated analog - the first 29 amino acids - of the 44-amino-acid native GHRH produced by the arcuate nucleus of the hypothalamus. The 1-29 fragment retains essentially the full growth-hormone-releasing activity of… Half-Life ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding) ~10-20 minutes (plasma; native GHRH 7 minutes) Typical Dose Range Without DAC: 100-300 mcg subcutaneous 1-3x daily (typically pre-bedtime); With DAC: 1000-2000 mcg subcutaneous once weekly — Dosing Frequency 1–3 times daily, typically before bed and/or upon waking — Administration Subcutaneous — Side Effects Expected / benign - Injection-site reaction — mild redness, itching, small bump; 24-48 hour resolution - Facial flushing / warmth 15-30 min post-injection (histamine release from GHRH action); typically diminishes after week 1-2 - Mild nausea in first week at… Common Effects - Injection site reactions — The most frequently reported issue. Mild erythema, transient itching, or a small wheal at the subcutaneous injection site. Usually self-resolves within 30-60 minutes and rarely requires intervention beyond site… Molecular Weight 3367.9 Da 3357.9 g/mol Common Vial Sizes 2mg, 5mg — ## Price History 2 data points - VANDL Labs - Ion Peptide ## Price History 5 data points - BM - Unknown - VANDL Labs - Ion Peptide - Disguised Alpha ### CJC-1295 (Mod GRF 1-29) — potential benefits - Preserves physiologic pulsatile GH secretion - Stimulates endogenous GH release (2-5x baseline per pulse) - 3-5x greater GH response when stacked with ipamorelin - Modest IGF-1 elevation (1.5-2x baseline) - Improved sleep depth and architecture - Enhanced recovery from exercise and injury - Body composition improvements (lean mass preservation, modest fat loss) - Lower desensitization risk vs CJC-1295 with DAC ### Sermorelin — potential benefits - Natural GH pulse stimulation - Improved sleep quality - Enhanced recovery and body composition - Anti-aging effects - Better skin elasticity - Increased lean muscle mass ## Frequently asked ### What's the difference between CJC-1295 (Mod GRF 1-29) and Sermorelin? CJC-1295 (Mod GRF 1-29) is a growth hormone / igf-1 axis that mod-grf 1-29 exerts its effect through a single, well-characterized receptor: the ghrh receptor (ghrhr) on anterior-pituitary somatotroph cells. the signaling cascade is the same…. Sermorelin is a growth hormone / igf-1 axis that ghrh receptor pharmacology sermorelin is a truncated analog - the first 29 amino acids - of the 44-amino-acid native ghrh produced by the arcuate nucleus of the hypothalamus. the…. The two differ in mechanism, half-life (~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding) vs ~10-20 minutes (plasma; native GHRH 7 minutes)), and typical dose range. ### Which has the longer half-life, CJC-1295 (Mod GRF 1-29) or Sermorelin? CJC-1295 (Mod GRF 1-29) has a half-life of ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding). Sermorelin has a half-life of ~10-20 minutes (plasma; native GHRH 7 minutes). Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, CJC-1295 (Mod GRF 1-29) or Sermorelin? Current lowest live price on BodyHackGuide: CJC-1295 (Mod GRF 1-29) from $29.00, Sermorelin from $24.99. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers. ### Can you stack CJC-1295 (Mod GRF 1-29) and Sermorelin? Stacking depends on mechanism overlap, safety profile, and goals. CJC-1295 (Mod GRF 1-29) and Sermorelin should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Live listings from the vendors we track, refreshed continuously. 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[View Vendor Scorecard](/vendors/scorecard) ## Related comparisons [CJC-1295 vs Ipamorelin](/compare/cjc-1295-vs-ipamorelin)[Tesamorelin vs CJC-1295](/compare/tesamorelin-vs-cjc-1295)[Sermorelin vs Ipamorelin](/compare/sermorelin-vs-ipamorelin)[Tesamorelin vs Sermorelin](/compare/tesamorelin-vs-sermorelin)[MK-677 vs CJC-1295](/compare/mk-677-vs-cjc-1295)[CJC-1295-Dac vs CJC-1295](/compare/cjc-1295-dac-vs-cjc-1295)[Ipamorelin vs MK-677](/compare/ipamorelin-vs-mk-677)[GHRP-2 vs GHRP-6](/compare/ghrp-2-vs-ghrp-6) **Research use only.** BodyHackGuide is a research and price-comparison reference. BodyHackGuide and BHG Labs share common ownership. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. 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