--- title: "CJC-1295 with DAC vs CJC-1295 (Mod GRF 1-29): Side-by-Side" description: "Compare CJC-1295 with DAC vs CJC-1295 (Mod GRF 1-29) — mechanism, half-life, dose range, side effects, and live vendor pricing. CJC-1295 with DAC from $34.99." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compare", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "CJC-1295 with DAC vs CJC-1295 (Mod GRF 1-29)" } ] }, { "@context": "https://schema.org", "@type": "WebPage", "name": "CJC-1295 with DAC vs CJC-1295 (Mod GRF 1-29): Side-by-Side Comparison (2026)", "description": "Compare CJC-1295 with DAC vs CJC-1295 (Mod GRF 1-29) — mechanism, half-life, dose range, side effects, and live vendor pricing. CJC-1295 with DAC from $34.99. CJC-1295 (Mod GRF 1-29) from $29.00. Side-by-side data from BodyHackGuide — we earn a commission on some vendor links.", "url": "https://www.bodyhackguide.co/compare/cjc-1295-dac-vs-cjc-1295", "dateModified": "2026-09-07", "isPartOf": { "@type": "WebSite", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" }, "mainEntity": { "@type": "ItemList", "itemListElement": [ { "@type": "ListItem", "position": 1, "item": { "@type": "Product", "name": "CJC-1295 with DAC", "description": "CJC-1295 with DAC (Drug Affinity Complex) is a modified form of CJC-1295 that incorporates a maleimidopropionic acid (MPA) reactive group at the C-terminus. Once injected, this MPA group forms a covalent thioether bond with free cysteine residues on serum albumin, effectively turning the small…", "url": "https://www.bodyhackguide.co/compound/cjc-1295-dac", "category": "Growth Hormone / IGF-1 Axis", "offers": { "@type": "AggregateOffer", "lowPrice": "34.99", "priceCurrency": "USD", "offerCount": 6 } } }, { "@type": "ListItem", "position": 2, "item": { "@type": "Product", "name": "CJC-1295 (Mod GRF 1-29)", "description": "CJC-1295 without DAC (also called Modified GRF 1-29 or MOD-GRF 1-29) is a 30-amino-acid analog of the first 29 residues of endogenous Growth Hormone Releasing Hormone (GHRH), with four strategic substitutions (D-Ala² for DPP-4 resistance, Gln⁸, Ala¹⁵, Leu²⁷) that extend its plasma half-life from <2…", "url": "https://www.bodyhackguide.co/compound/cjc-1295", "category": "Growth Hormone / IGF-1 Axis", "offers": { "@type": "AggregateOffer", "lowPrice": "29.00", "priceCurrency": "USD", "offerCount": 6 } } } ] } }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What's the difference between CJC-1295 with DAC and CJC-1295 (Mod GRF 1-29)?", "acceptedAnswer": { "@type": "Answer", "text": "CJC-1295 with DAC is a growth hormone / igf-1 axis that cjc-1295 with dac has the same pharmacodynamic mechanism as the non-dac variant (ghrh receptor agonism on pituitary somatotrophs) but radically different pharmacokinetics. 1.…. CJC-1295 (Mod GRF 1-29) is a growth hormone / igf-1 axis that mod-grf 1-29 exerts its effect through a single, well-characterized receptor: the ghrh receptor (ghrhr) on anterior-pituitary somatotroph cells. the signaling cascade is the same…. The two differ in mechanism, half-life (6–8 days (due to albumin binding via DAC) vs ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding)), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, CJC-1295 with DAC or CJC-1295 (Mod GRF 1-29)?", "acceptedAnswer": { "@type": "Answer", "text": "CJC-1295 with DAC has a half-life of 6–8 days (due to albumin binding via DAC). CJC-1295 (Mod GRF 1-29) has a half-life of ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding). Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Which is cheaper, CJC-1295 with DAC or CJC-1295 (Mod GRF 1-29)?", "acceptedAnswer": { "@type": "Answer", "text": "Current lowest live price on BodyHackGuide: CJC-1295 with DAC from $34.99, CJC-1295 (Mod GRF 1-29) from $29.00. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers." } }, { "@type": "Question", "name": "Can you stack CJC-1295 with DAC and CJC-1295 (Mod GRF 1-29)?", "acceptedAnswer": { "@type": "Answer", "text": "Stacking depends on mechanism overlap, safety profile, and goals. CJC-1295 with DAC and CJC-1295 (Mod GRF 1-29) should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds." } } ] } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fcompare%2Fcjc-1295-dac-vs-cjc-1295) 100K+ researchers trust BodyHackGuide — Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) 1. [Home](/) 2. [Compare](/compare) 3. CJC-1295 with DAC vs CJC-1295 (Mod GRF 1-29) # CJC-1295 with DAC vs CJC-1295 (Mod GRF 1-29) Side-by-side comparison of CJC-1295 with DAC and CJC-1295 (Mod GRF 1-29): mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land. CJC-1295 with DAC from $34.99 CJC-1295 (Mod GRF 1-29) from $29.00 ## Live price snapshot ### CJC-1295 with DAC Current low $59.99 as of Sep 5, 2026 7-day low $59.99 30-day low $59.99 30-day change — baseline building ### CJC-1295 (Mod GRF 1-29) Current low $49.00 as of Apr 22, 2026 7-day low — no 7d data yet 30-day low — no 30d data yet 30-day change — baseline building ## CJC-1295 with DAC CJC-1295 with DAC (Drug Affinity Complex) is a modified form of CJC-1295 that incorporates a maleimidopropionic acid (MPA) reactive group at the C-terminus. Once injected, this MPA group forms a covalent thioether bond… **Live lowest price:** $34.99 across 6 vendors [Full CJC-1295 with DAC profile](/compound/cjc-1295-dac) ## CJC-1295 (Mod GRF 1-29) Featured CJC-1295 without DAC (also called Modified GRF 1-29 or MOD-GRF 1-29) is a 30-amino-acid analog of the first 29 residues of endogenous Growth Hormone Releasing Hormone (GHRH), with four strategic substitutions (D-Ala² for… **Live lowest price:** $29.00 across 6 vendors [Full CJC-1295 (Mod GRF 1-29) profile](/compound/cjc-1295) ## Side-by-side comparison Attribute CJC-1295 with DAC CJC-1295 (Mod GRF 1-29) Category Growth Hormone / IGF-1 Axis Growth Hormone / IGF-1 Axis Research Stage Phase II Phase 2 (clinical development discontinued) Mechanism of Action CJC-1295 with DAC has the same pharmacodynamic mechanism as the non-DAC variant (GHRH receptor agonism on pituitary somatotrophs) but radically different pharmacokinetics. 1. Albumin conjugation - the central pharmacokinetic feature - The MPA… MOD-GRF 1-29 exerts its effect through a single, well-characterized receptor: the GHRH receptor (GHRHR) on anterior-pituitary somatotroph cells. The signaling cascade is the same as endogenous GHRH; the difference is pharmacokinetics. 1. GHRH receptor agonism… Half-Life 6–8 days (due to albumin binding via DAC) ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding) Typical Dose Range 1,000–2,000 mcg (1–2 mg) per injection Without DAC: 100-300 mcg subcutaneous 1-3x daily (typically pre-bedtime); With DAC: 1000-2000 mcg subcutaneous once weekly Dosing Frequency Once per week 1–3 times daily, typically before bed and/or upon waking Administration Subcutaneous Subcutaneous Side Effects Expected / benign - Injection-site reaction — redness, slight swelling, itching at the weekly injection - Facial flushing / warmth post-injection, sometimes lasting hours (longer than with MOD-GRF 1-29) - Vivid dreams — very common in first weeks - Mild nausea… Expected / benign - Injection-site reaction — mild redness, itching, small bump; 24-48 hour resolution - Facial flushing / warmth 15-30 min post-injection (histamine release from GHRH action); typically diminishes after week 1-2 - Mild nausea in first week at… Molecular Weight ~3647 Da 3367.9 Da Common Vial Sizes 2mg, 5mg 2mg, 5mg ## Price History 4 data points - BM - VANDL Labs - Ion Peptide - Disguised Alpha ## Price History 2 data points - VANDL Labs - Ion Peptide ### CJC-1295 with DAC — potential benefits - Sustained IGF-1 elevation (1.5-3x baseline) for 28+ days - Convenient weekly subcutaneous dosing - Improved body composition (lean mass, fat loss) - Enhanced recovery from training and injury - Albumin conjugation extends half-life to ~8 days - Stimulates endogenous GH production vs exogenous replacement - Dose-dependent GH elevation 2-10x baseline - Phase 1 clinical data in 50 healthy adults (Teichman 2006) ### CJC-1295 (Mod GRF 1-29) — potential benefits - Preserves physiologic pulsatile GH secretion - Stimulates endogenous GH release (2-5x baseline per pulse) - 3-5x greater GH response when stacked with ipamorelin - Modest IGF-1 elevation (1.5-2x baseline) - Improved sleep depth and architecture - Enhanced recovery from exercise and injury - Body composition improvements (lean mass preservation, modest fat loss) - Lower desensitization risk vs CJC-1295 with DAC ## Frequently asked ### What's the difference between CJC-1295 with DAC and CJC-1295 (Mod GRF 1-29)? CJC-1295 with DAC is a growth hormone / igf-1 axis that cjc-1295 with dac has the same pharmacodynamic mechanism as the non-dac variant (ghrh receptor agonism on pituitary somatotrophs) but radically different pharmacokinetics. 1.…. CJC-1295 (Mod GRF 1-29) is a growth hormone / igf-1 axis that mod-grf 1-29 exerts its effect through a single, well-characterized receptor: the ghrh receptor (ghrhr) on anterior-pituitary somatotroph cells. the signaling cascade is the same…. The two differ in mechanism, half-life (6–8 days (due to albumin binding via DAC) vs ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding)), and typical dose range. ### Which has the longer half-life, CJC-1295 with DAC or CJC-1295 (Mod GRF 1-29)? CJC-1295 with DAC has a half-life of 6–8 days (due to albumin binding via DAC). CJC-1295 (Mod GRF 1-29) has a half-life of ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding). Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Which is cheaper, CJC-1295 with DAC or CJC-1295 (Mod GRF 1-29)? Current lowest live price on BodyHackGuide: CJC-1295 with DAC from $34.99, CJC-1295 (Mod GRF 1-29) from $29.00. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers. ### Can you stack CJC-1295 with DAC and CJC-1295 (Mod GRF 1-29)? Stacking depends on mechanism overlap, safety profile, and goals. CJC-1295 with DAC and CJC-1295 (Mod GRF 1-29) should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Live listings from the vendors we track, refreshed continuously. 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