--- title: "Astragalus vs SS-31: Side-by-Side Comparison (2026)" url: https://www.bodyhackguide.co/compare/astragalus-vs-ss-31 description: "Compare Astragalus vs SS-31 side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) # Astragalus (Huang Qi) vs SS-31 Side-by-side comparison of Astragalus (Huang Qi) and SS-31: mechanism, half-life, dose range, safety profile, and vendor pricing. Astragalus (Huang Qi): no price on file SS-31 from $72.00 ## Price snapshot ### Astragalus (Huang Qi) Current low — 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ### SS-31 Current low $72.00 current listings 7-day low — not enough history yet 30-day low — not enough history yet 30-day change — not enough history yet ## Astragalus (Huang Qi) Astragalus (scientific name Astragalus membranaceus, also classified as Astragalus mongholicus or Astragalus propinquus; called Huang Qi / Θ╗äΦè¬ in Mandarin Chinese — literally "yellow leader" referring to the yellow… No vendor price on file. Full Astragalus (Huang Qi) profile (https://www.bodyhackguide.co/compound/astragalus) ## SS-31 Featured SS-31 (elamipretide; MTP-131; formerly Bendavia; chemical sequence D-Arg-Dmt-Lys-Phe-NH2 with dimethyltyrosine at position 2) is a first-in-class aromatic-cationic tetrapeptide designed to selectively target the inner… **Lowest listed price:** $72.00 across 4 listings Full SS-31 profile (https://www.bodyhackguide.co/compound/ss-31) ## Side-by-side comparison | Attribute | Astragalus (Huang Qi) | SS-31 | | --- | --- | --- | | Category | Adaptogen | Mitochondrial Peptides | | Research Stage | Preclinical | Clinical/Approved | | Mechanism of Action | Astragalus (Astragalus membranaceus) operates through multiple pharmacologic mechanisms reflecting its complex phytochemistry. The major active fractions — astragalus polysaccharides (APS), astragalosides (particularly astragaloside IV), cycloastragenol, and… | SS-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high concentration of cardiolipin, a signature mitochondrial anionic phospholipid - to… | | Half-Life | — | ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding | | Typical Dose Range | — | 20-60 mg | | Dosing Frequency | — | Once daily subcutaneous (some protocols use 5-6 days per week) | | Administration | — | — | | Side Effects | Safety is generally excellent — consistent with astragalus's "superior grade" classical TCM classification and millennia of widespread medicinal and culinary use. Adverse effects at typical doses of quality preparations are uncommon and usually mild. Key… | SS-31 (elamipretide) has been generally well-tolerated across clinical trials spanning over a decade of human exposure, with adverse event profiles dominated by injection site reactions rather than systemic toxicity. This favorable safety profile reflects both… | | Molecular Weight | — | 639.8 g/mol | | Common Vial Sizes | — | — | ## Price History 2 data points - Ion Peptide - BHG Labs ## Frequently asked ### What's the difference between Astragalus (Huang Qi) and SS-31? Astragalus (Huang Qi) is a adaptogen that astragalus (astragalus membranaceus) operates through multiple pharmacologic mechanisms reflecting its complex phytochemistry. the major active fractions — astragalus…. SS-31 is a mitochondrial peptides that ss-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high…. The two differ in mechanism, half-life (not reported vs ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding), and typical dose range. ### Which has the longer half-life, Astragalus (Huang Qi) or SS-31? Astragalus (Huang Qi) has a half-life of not reported. SS-31 has a half-life of ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding. Longer half-lives generally mean less frequent dosing but slower on/off kinetics. ### Can you stack Astragalus (Huang Qi) and SS-31? Stacking depends on mechanism overlap, safety profile, and goals. Astragalus (Huang Qi) and SS-31 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds. ## See current vendor prices Listings from the vendors we track. Prices change often, so check the vendor before you buy. Astragalus (Huang Qi) prices: https://www.bodyhackguide.co/compound/astragalus?tab=prices SS-31 prices: https://www.bodyhackguide.co/compound/ss-31?tab=prices Compare all compounds: https://www.bodyhackguide.co/compare ### Before you buy Astragalus (Huang Qi) or SS-31 Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor. View Vendor Scorecard (https://www.bodyhackguide.co/vendors/scorecard) ## Related comparisons MOTS C vs SS-31: https://www.bodyhackguide.co/compare/mots-c-vs-ss-31 **Research use only.** BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards (https://www.bodyhackguide.co/editorial-standards) and affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). BodyHackGuide (https://www.bodyhackguide.co/) Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology). Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. - Terms: https://www.bodyhackguide.co/terms - Privacy: https://www.bodyhackguide.co/privacy ## Structured data ```json [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Compare", "item": "https://www.bodyhackguide.co/compare" }, { "@type": "ListItem", "position": 3, "name": "Astragalus (Huang Qi) vs SS-31" } ] }, { "@context": "https://schema.org", "@type": "WebPage", "name": "Astragalus vs SS-31: Side-by-Side Comparison (2026)", "description": "Compare Astragalus vs SS-31 side by side. We earn a commission on some vendor links. Mechanism, half-life, dose range, side effects and prices.", "url": "https://www.bodyhackguide.co/compare/astragalus-vs-ss-31", "dateModified": "2026-10-26", "isPartOf": { "@type": "WebSite", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" }, "mainEntity": { "@type": "ItemList", "itemListElement": [ { "@type": "ListItem", "position": 1, "item": { "@type": "Product", "name": "Astragalus (Huang Qi)", "description": "Astragalus (scientific name Astragalus membranaceus, also classified as Astragalus mongholicus or Astragalus propinquus; called Huang Qi / Θ╗äΦè¬ in Mandarin Chinese — literally \"yellow leader\" referring to the yellow interior of the root; known in Western herbalism as milk vetch root or simply…", "url": "https://www.bodyhackguide.co/compound/astragalus", "category": "Adaptogen" } }, { "@type": "ListItem", "position": 2, "item": { "@type": "Product", "name": "SS-31", "description": "SS-31 (elamipretide; MTP-131; formerly Bendavia; chemical sequence D-Arg-Dmt-Lys-Phe-NH2 with dimethyltyrosine at position 2) is a first-in-class aromatic-cationic tetrapeptide designed to selectively target the inner mitochondrial membrane and bind cardiolipin, the signature mitochondrial…", "url": "https://www.bodyhackguide.co/compound/ss-31", "category": "Mitochondrial Peptides", "offers": { "@type": "AggregateOffer", "lowPrice": "72.00", "priceCurrency": "USD", "offerCount": 4 } } } ] } }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 273 compound profiles, interactive dosing calculators, vendor price comparisons, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. We earn a commission on purchases through some of our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What's the difference between Astragalus (Huang Qi) and SS-31?", "acceptedAnswer": { "@type": "Answer", "text": "Astragalus (Huang Qi) is a adaptogen that astragalus (astragalus membranaceus) operates through multiple pharmacologic mechanisms reflecting its complex phytochemistry. the major active fractions — astragalus…. SS-31 is a mitochondrial peptides that ss-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high…. The two differ in mechanism, half-life (not reported vs ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding), and typical dose range." } }, { "@type": "Question", "name": "Which has the longer half-life, Astragalus (Huang Qi) or SS-31?", "acceptedAnswer": { "@type": "Answer", "text": "Astragalus (Huang Qi) has a half-life of not reported. SS-31 has a half-life of ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding. Longer half-lives generally mean less frequent dosing but slower on/off kinetics." } }, { "@type": "Question", "name": "Can you stack Astragalus (Huang Qi) and SS-31?", "acceptedAnswer": { "@type": "Answer", "text": "Stacking depends on mechanism overlap, safety profile, and goals. Astragalus (Huang Qi) and SS-31 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds." } } ] } ] ```