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title: "5-Amino-1MQ vs Tirzepatide: Side-by-Side Comparison (2026)"
description: "Compare 5-Amino-1MQ vs Tirzepatide — mechanism, half-life, dose range, side effects, and live vendor pricing. 5-Amino-1MQ from $29.99. Tirzepatide from $49.00."
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1.  [Home](/)
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3.  5-Amino-1MQ vs Tirzepatide 

# 5-Amino-1MQ vs  Tirzepatide

Side-by-side comparison of 5-Amino-1MQ and Tirzepatide: mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land.

5-Amino-1MQ from $29.99

Tirzepatide from $49.00

## Live price snapshot

### 5-Amino-1MQ

Current low

$39.99

as of Sep 5, 2026

7-day low

$39.99

30-day low

$39.99

30-day change

— 

baseline building

### Tirzepatide

Current low

$69.99

as of Sep 5, 2026

7-day low

$69.99

30-day low

$69.99

30-day change

— 

baseline building

## 5-Amino-1MQ

5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to…

**Live lowest price:** $29.99 across 14 vendors

[Full 5-Amino-1MQ profile](/compound/5-amino-1mq)

## Tirzepatide

Featured

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist with a molecular weight of 4813.45 Da and CAS number 2023788-19-2. It is a 39-amino-acid…

**Live lowest price:** $49.00 across 17 vendors

[Full Tirzepatide profile](/compound/tirzepatide)

## Side-by-side comparison

Attribute

5-Amino-1MQ

Tirzepatide

Category 

Weight Loss

Metabolic & Weight Loss

Research Stage 

Preclinical

FDA Approved

Mechanism of Action 

5-Amino-1MQ works by inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to the nitrogen of nicotinamide (vitamin B3 amide), producing 1-methylnicotinamide (1-MNA) and…

Dual GLP-1 and GIP Receptor Agonism Tirzepatide simultaneously activates two incretin receptors: the GLP-1 receptor and the GIP receptor. While the GLP-1 receptor component provides the well-established effects of GLP-1 agonism (glucose-dependent insulin…

Half-Life 

~6–12 hours (oral)

~5 days (approximately 120 hours), enabled by C20 fatty diacid albumin-binding modification

Typical Dose Range 

50 mg - 150 mg daily (oral or injection)

2500 mcg (2.5 mg) starting dose, titrated every 4 weeks through 5000, 7500, 10000, 12500, to 15000 mcg (15 mg) maximum weekly dose

Dosing Frequency 

Once daily oral

Once weekly subcutaneous injection

Administration 

Oral

Subcutaneous (weekly)

Side Effects 

The side effect profile of 5-amino-1MQ in humans is not documented because there are no human clinical trials. Rodent studies report generally good tolerability at doses producing metabolic and muscle benefits, without obvious signs of hepatotoxicity,…

Mild to moderate nausea (especially at initiation), headache, fatigue, constipation or diarrhea, abdominal distension. Injection site reactions. Rare: hypoglycemia, increased heart rate, pancreatitis.

Molecular Weight 

159.21 g/mol

4813.5 Da

Common Vial Sizes 

50mg capsules, 100mg capsules

5mg, 10mg, 15mg

## Price History

5 data points 

-   OF 
-   BM 
-   VANDL Labs 
-   Unknown 
-   Ion Peptide 
-   Disguised Alpha 

## Price History

5 data points 

-   OF 
-   BM 
-   Unknown 
-   VANDL Labs 
-   Ion Peptide 
-   Disguised Alpha 

### 5-Amino-1MQ — potential benefits

-   Enhanced fat metabolism and weight loss 
-   Increased NAD+ levels in adipose tissue 
-   Improved cellular energy production 
-   Anti-aging properties via sirtuin activation 

### Tirzepatide — potential benefits

-   Mean body weight reduction of 22.5% at 72 weeks - highest of any anti-obesity medication (PMID: 35658024) 
-   36.2% of participants achieved greater than or equal to 25% body weight loss (PMID: 35658024) 
-   Significant HbA1c reduction in type 2 diabetes (up to 2.4% at 40 weeks in the SURPASS-5 add-on-to-insulin trial) (PMID: 35133415) 
-   Potentially superior lean mass preservation versus GLP-1-only agents due to GIP component 
-   Dual incretin mechanism providing complementary metabolic benefits 
-   Improved lipid profiles including triglycerides, LDL cholesterol, and HDL cholesterol 
-   Reduction in waist circumference and markers of visceral adiposity (PMID: 37840095) 

## Frequently asked

### What's the difference between 5-Amino-1MQ and Tirzepatide?

5-Amino-1MQ is a weight loss that 5-amino-1mq works by inhibiting nicotinamide n-methyltransferase (nnmt), an enzyme that catalyzes the transfer of a methyl group from s-adenosyl-l-methionine (sam) to the nitrogen…. Tirzepatide is a metabolic & weight loss that dual glp-1 and gip receptor agonism tirzepatide simultaneously activates two incretin receptors: the glp-1 receptor and the gip receptor. while the glp-1 receptor component…. The two differ in mechanism, half-life (~6–12 hours (oral) vs ~5 days (approximately 120 hours), enabled by C20 fatty diacid albumin-binding modification), and typical dose range.

### Which has the longer half-life, 5-Amino-1MQ or Tirzepatide?

5-Amino-1MQ has a half-life of ~6–12 hours (oral). Tirzepatide has a half-life of ~5 days (approximately 120 hours), enabled by C20 fatty diacid albumin-binding modification. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.

### Which is cheaper, 5-Amino-1MQ or Tirzepatide?

Current lowest live price on BodyHackGuide: 5-Amino-1MQ from $29.99, Tirzepatide from $49.00. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers.

### Can you stack 5-Amino-1MQ and Tirzepatide?

Stacking depends on mechanism overlap, safety profile, and goals. 5-Amino-1MQ and Tirzepatide should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.

## See current vendor prices

Live listings from the vendors we track, refreshed continuously.

[5-Amino-1MQ prices](/compound/5-amino-1mq?tab=prices) [Tirzepatide prices](/compound/tirzepatide?tab=prices) [Compare all compounds](/compare)

### Before you buy 5-Amino-1MQ or Tirzepatide

Check the vendor trust score. Every supplier we track is rated 0–100 on COA verification, payment transparency, shipping, reviews, and listings — one published, reproducible methodology, applied to every vendor including BHG Labs, which shares our ownership.

[View Vendor Scorecard](/vendors/scorecard)

## Related comparisons

[Retatrutide vs Tirzepatide](/compare/retatrutide-vs-tirzepatide)[Tirzepatide vs Semaglutide](/compare/tirzepatide-vs-semaglutide)[Mazdutide vs Tirzepatide](/compare/mazdutide-vs-tirzepatide)[AOD-9604 vs Tirzepatide](/compare/aod-9604-vs-tirzepatide)[Retatrutide vs Semaglutide](/compare/retatrutide-vs-semaglutide)[Orforglipron vs Semaglutide](/compare/orforglipron-vs-semaglutide)[AOD-9604 vs Semaglutide](/compare/aod-9604-vs-semaglutide)

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